Interactions between U and V sex chromosomes during the life cycle of Ectocarpus [0.03%]
Ectocarpus的生命週期中U和V性染色體的相互作用
Jeromine Vigneau,Claudia Martinho,Olivier Godfroy et al.
Jeromine Vigneau et al.
In many animals and flowering plants, sex determination occurs in the diploid phase of the life cycle with XX/XY or ZW/ZZ sex chromosomes. However, in early diverging plants and most macroalgae, sex is determined by female (U) or male (V) s...
A Rad50-null mutation in mouse germ cells causes reduced DSB formation, abnormal DSB end resection and complete loss of germ cells [0.03%]
Rad50突变小鼠生殖细胞中DSB形成减少、末端切除异常及生殖细胞完全丧失
Yuefang Liu,Zhen Lin,Junyi Yan et al.
Yuefang Liu et al.
The conserved MRE11-RAD50-NBS1/Xrs2 complex is crucial for DNA break metabolism and genome maintenance. Although hypomorphic Rad50 mutation mice showed normal meiosis, both null and hypomorphic rad50 mutation yeast displayed impaired meiosi...
40 years of the homeobox: either it is wrong or it is quite interesting [0.03%]
家盒基因40年：要么大错特错，要么有趣万分
Matthew P Scott
Matthew P Scott
Many genes that regulate development share a 180 bp DNA sequence, called the homeobox, encoding a 60 amino acid DNA-binding domain ( McGinnis et al., 1984c; Scott and Weiner, 1984). Because the homeobox is long enough to hybridize to relate...
Alex Eve,Oliver Hobert
Alex Eve
William McGinnis,Michael Levine
William McGinnis
This is a personal, non-linear summary of the discovery of the homeobox, a short DNA sequence encoding a DNA-binding domain conserved in developmental control genes. It is based on our recollections, a few decaying lab notebooks and letters...
Temporally distinct roles of Aurora A in polarization of the C. elegans zygote [0.03%]
Aurora A在C.elegans受精卵极化中的时间不同的角色
Nadia I Manzi,Bailey N de Jesus,Yu Shi et al.
Nadia I Manzi et al.
During asymmetric cell division, cell polarity is coordinated with the cell cycle to allow proper inheritance of cell fate determinants and the generation of cellular diversity. In the Caenorhabditis elegans zygote, polarity is governed by ...
The art of observation: bridging science and art to see the unexpected [0.03%]
观察的艺术：融合科学与艺术以预见想不到的事物
Lauren E Gonzalez,Haoyang Wei,Valentina Greco et al.
Lauren E Gonzalez et al.
Observation is the heart of research, but it can be challenging to observe deeply and go beyond expected observations. Here, we describe activities designed for scientists to enhance their observational skills by engaging with art. In colla...
Adhesion and shrinkage transform the rounded pupal horn into an angular adult horn in Japanese rhinoceros beetle [0.03%]
粘附和收缩将日本犀牛甲虫的圆形蛹角变成棱角分明的成虫角
Keisuke Matsuda,Haruhiko Adachi,Hiroki Gotoh et al.
Keisuke Matsuda et al.
Clarifying the mechanisms underlying shape alterations during insect metamorphosis is important for understanding exoskeletal morphogenesis. The large horn of the Japanese rhinoceros beetle Trypoxylus dichotomus is the result of drastic met...
Dissecting the dynamic cellular transcriptional atlas of adult teleost testis development throughout the annual reproductive cycle [0.03%]
解析全年生殖周期中成年硬骨鱼睾丸发育的动态细胞转录图谱
Chaofan Jin,Kai Yan,Mengya Wang et al.
Chaofan Jin et al.
Teleost testis development during the annual cycle involves dramatic changes in cellular compositions and molecular events. In this study, the testicular cells derived from adult black rockfish at distinct stages - regressed, regenerating a...
Sexually dimorphic dynamics of the microtubule network in medaka (Oryzias latipes) germ cells [0.03%]
米氏裂腹鱼(奥蕊兹奥蒂斯)生殖细胞中微管网络的性别二态性动态变化
Mariko Kikuchi,Miyo Yoshimoto,Tokiro Ishikawa et al.
Mariko Kikuchi et al.
Gametogenesis is the process through which germ cells differentiate into sexually dimorphic gametes, eggs and sperm. In the teleost fish medaka (Oryzias latipes), a germ cell-intrinsic sex determinant, foxl3, triggers germline feminization ...