Dissecting planar and vertical organiser signals in early chick neural development [0.03%]
鸡早期神经发育中组织信号的平面和垂直解剖学研究
Alexandra S Neaverson,Benjamin J Steventon
Alexandra S Neaverson
Early neural development involves a combination of planar signals from the vertebrate organiser and vertical signals from its derived structures, the prechordal plate and notochord, together with early permissive signals from the hypoblast ...
Real-time transcriptomic profiling of hPSC-derived cartilage during development identifies a key role for the extracellular matrix in homeostasis and protection [0.03%]
实时转录组谱分析发现细胞外基质在软骨发育、稳态和保护中的关键作用
Rosanne M Raftery,Steven K Pregizer,Suyash Raj et al.
Rosanne M Raftery et al.
Articular and growth plate chondrocytes share a common progenitor but diverge during development to generate distinct cartilage tissues specific to their functions; permanent articular chondrocytes produce and maintain a frictionless surfac...
Maxim V C Greenberg
Maxim V C Greenberg
The term 'housekeeping gene' evokes a sense of banality. These are the boring genes that hum in the background, impervious to cell state or stress. For a developmental biologist captivated by the impact of differentiation or environmental c...
PBX-dependent and -independent Hox programs establish and maintain motor neuron terminal identity [0.03%]
依赖和不依赖PBX的Hox程序建立并保持运动神经元末端身份
Manasa Prahlad,Weidong Feng,Ian Q Weigle et al.
Manasa Prahlad et al.
Motor neuron (MN) diversity is essential for generating animal movement, yet the molecular mechanisms specifying MN subtypes remain poorly understood. We investigate how Hox genes and their PBX co-factors establish cholinergic MN identity a...
NUDT21 regulates 3'UTR dynamics in epididymal principal cells to preserve sperm integrity [0.03%]
NUDT21通过调节附睾主细胞的3'UTR动力学来维持精子完整性
Jinzhao Zhou,Han Yang,Shan Li et al.
Jinzhao Zhou et al.
In mammals, the epididymis is composed of pseudostratified epithelium that forms the post-testicular milieu for spermatozoa. To date, the role of epithelial cells in shaping the luminal microenvironment for spermatozoa remains poorly unders...
Cell size control emerges from the vein-dependent coordinated divisions of distinct cell groups in Drosophila wing [0.03%]
斑翅果蝇翼中独立细胞组的 veins 依赖型协调分裂调控细胞大小
Kaoru Sugimura,Ryu Takayanagi,Toshinori Namba et al.
Kaoru Sugimura et al.
During morphogenesis, cell divisions are precisely regulated in space and time. The biological objectives achieved by such regulation are not fully understood. Here, by applying a newly developed lineage-reconstruction pipeline to Drosophil...
How cell size is regulated is a fundamental question in developmental biology. In their work, Kaoru Sugimura and colleagues use live imaging and quantitative modelling to reveal a mechanism by which precise cell-size control emerges from th...
The people behind the papers - Zhainib Amir-Ugokwe and Kristy Red-Horse [0.03%]
论文背后的人——Zhainib Amir-Ugokwe和Kristy Red-Horse
During human vascular development and regeneration, arterial cells can be made from both mesodermal and venous cells. Whilst in vitro human models of mesodermal to arterial conversion have been established, studies of arterial development a...
In preprints: toward a holistic lineage-tracing map of mammalian embryogenesis [0.03%]
预印本：走向哺乳动物胚胎发生整体系谱图
Yingying Chen,Xianfa Yang
Yingying Chen