Nia Teerikorpi,Kate E McCluskey,Ethel Bader et al.
Nia Teerikorpi et al.
Autism spectrum disorder (ASD) and congenital heart disease (CHD) frequently co-occur, yet the underlying molecular mechanisms of this comorbidity remain unknown. Given that children with CHD are identified as newborns, understanding which ...
TIE1 dependent lymphatic vascular remodeling is mediated by its second tyrosine kinase domain [0.03%]
TYRO蛋白第二个酪氨酸激酶结构域介导淋巴管重构
H Scott Baldwin,Michael J Davis,Cristina Harmelink et al.
H Scott Baldwin et al.
Mutations in ANG2 and TIE1 are associated with primary lymphedema in humans, but the mechanisms of ANG/TIE signaling in the lymphatic vasculature remain incompletely understood. We document that TIE2 is not detected in lymphatic endothelial...
Mansi Srivastava is Professor of Organismic and Evolutionary Biology at Harvard University, USA, where her group has developed the three-banded panther worm (Hofstenia miamia) as a model system in which to study whole-body regeneration. Thi...
Mesenchymal SLMAP coordinates with MST3 to govern gut elongation during development [0.03%]
间充质SLMAP通过与MST3协同作用调控肠道发育过程中的伸长生长
Yuwei Pan,Shiyang Wang,Wuqi Yang et al.
Yuwei Pan et al.
Developing gut in mice undergoes rapid elongation during late embryogenesis, yet significantly slows down after birth. Precise regulatory mechanism of this dynamic morphogenetic process remains unknown. Utilizing single-cell RNA-sequencing ...
Kristian Saied-Santiago,Melissa Baxter,Jaffna Mathiaparanam et al.
Kristian Saied-Santiago et al.
Optic nerve (ON) regeneration in mammalian systems is limited by an overshadowing dominance of inhibitory factors. This has severely hampered the identification of pro-regenerative pathways. Here, we take advantage of the regenerative capac...
Andrea Rix,Binyam Mogessie
Andrea Rix
Yu-Hao Liu,Robert Schneider
Yu-Hao Liu
In eukaryotic cells, the genetic material is organized into chromatin, which consists mainly of DNA, histones and chromatin-associated proteins. An important regulator of chromatin structure and function are histone post-translational modif...
Bulk-level maps of pioneer factor binding dynamics during Drosophila maternal-to-zygotic transition [0.03%]
果蝇母体-合子转换期间先锋因子结合的批量图谱
Sadia Siddika Dima,Gregory T Reeves
Sadia Siddika Dima
Gene regulation by transcription factors (TFs) binding cognate sequences is of paramount importance. For example, the TFs Zelda (Zld) and GAGA factor (GAF) are widely acknowledged for pioneering gene activation during zygotic genome activat...
Jan Żylicz is an Associate Professor at the Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, within the University of Copenhagen, Denmark. Jan's work bridges the fields of epigenetics, chromatin and metabolism to understand th...
In preprints: unpicking chemical and mechanical crosstalk for axonal pathfinding [0.03%]
【预印本】解析化学和机械信号的相互作用在轴突导向中的作用
Dionn Hargreaves,Sarah Woolner
Dionn Hargreaves