Misty Riddle is an Assistant Professor at the University of Nevada, Reno, USA. Her research group uses the Mexican tetra, Astyanax mexicanus, to understand how genetic changes alter development and drive the evolution of morphology and phys...
A GTPase regulatory protein, PXF-1, is required for synapse development through an actin-mediated mechanism in Caenorhabditis elegans. In this work, Salvatore Cherra and colleagues show that two conserved guanine exchange factors are activa...
The transition of plants from water to land included the evolution from two-dimensional (2D) to three-dimensional (3D) growth. In their work, Laura Moody and colleagues identify a new factor that encodes aFLOE-related protein, which is esse...
Supracellular actomyosin assemblies: master coordinators of development [0.03%]
超细胞肌动蛋白肌球蛋白装配结构：发育的总指挥官
Katja Röper
Katja Röper
Most movement in biological systems is driven by assemblies of actomyosin, be it in the form of sarcomeres in muscles or as actomyosin networks in non-muscle cells. Actomyosin has several key functions within epithelial cells, the cells tha...
Morphogenetic processes during gastrulation and neurulation require tight coordination of the actin cytoskeleton; however, the gene regulatory mechanisms that influence this process remain unclear. In a new study, Itoh and colleagues invest...
A developmental atlas of zebrafish gills links early vascular patterning to adult architecture [0.03%]
斑马鱼鳃的发育图谱将早期血管模式与成人结构联系起来
Mathieu Preußner,Anna Mertens,Marion Basoglu et al.
Mathieu Preußner et al.
Gills are essential for fish respiration and have a highly specialized cellular architecture enabling efficient gas exchange. Surprisingly, the developmental processes underlying gill formation in zebrafish remain poorly understood. Here, w...
Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans [0.03%]
秀丽隐杆线虫雄性特异性神经系统中普遍存在同源框基因功能
Robert W Fernandez,Angelo J Digirolamo rd,Giulio Valperga et al.
Robert W Fernandez et al.
We explore here how neuronal cell type diversity is genetically delineated in the context of the large, but poorly studied, male-specific nervous system of the nematode Caenorhabditis elegans. Mostly during postembryonic development, the C....
FGF diffusion is required for directed migration of postembryonic muscle progenitors in C. elegans [0.03%]
成纤维细胞生长因子扩散是C. elegans胚胎后肌原细胞定向迁移的必要条件
Theresa V Gibney,Ariel M Pani
Theresa V Gibney
Extracellular signaling molecules mediate crucial aspects of cell-cell communication and play essential roles in development and homeostasis. Fibroblast Growth Factors (FGFs) are a family of secreted signaling proteins that can disperse lon...
A transcription factor toggle switch determines differentiated epidermal cell identities in Hydra [0.03%]
水螅分化表皮细胞身份由转录因子双稳态开关决定
Jaroslav Ferenc,Marylène Bonvin,Panagiotis Papasaikas et al.
Jaroslav Ferenc et al.
In Hydra, a simple cnidarian model, epithelio-muscular cells shape and maintain body architecture through continuous renewal. Undifferentiated cells from the mid-body region migrate passively toward the extremities, replacing shed cells and...
Correction: PLAC8, a new marker for human interstitial extravillous trophoblast cells, promotes their invasion and migration [0.03%]
PLAC8是一种新的异染性细胞滋养层标志物，可促进侵袭和迁移能力校正通知
Wen-Lin Chang,Ya-Wei Liu,Yan-Li Dang et al.
Wen-Lin Chang et al.
Published Erratum
Development (Cambridge, England). 2025 Aug 1;152(15):dev204982. DOI:10.1242/dev.204982 2025