A mathematical model of cardiovascular dynamics for the diagnosis and prognosis of hemorrhagic shock [0.03%]
用于出血性休克诊断和预后的心血管动力学数学模型
Laura DOrsi,Luciano Curcio,Fabio Cibella et al.
Laura DOrsi et al.
A variety of mathematical models of the cardiovascular system have been suggested over several years in order to describe the time-course of a series of physiological variables (i.e. heart rate, cardiac output, arterial pressure) relevant f...
Classification under uncertainty: data analysis for diagnostic antibody testing [0.03%]
不确定性下的分类问题:诊断抗体检测中的数据分析
Paul N Patrone,Anthony J Kearsley
Paul N Patrone
Formulating accurate and robust classification strategies is a key challenge of developing diagnostic and antibody tests. Methods that do not explicitly account for disease prevalence and uncertainty therein can lead to significant classifi...
Daniel M Anderson,Maria Corsaro,Jonathan Horton et al.
Daniel M Anderson et al.
We develop a lubrication theory-based mathematical model that describes the dynamics of a tear film during blinking and contact lens (CL) wear. The model extends previous work on pre-corneal tear film dynamics during blinking by coupling th...
A mathematical framework for modelling 3D cell motility: applications to glioblastoma cell migration [0.03%]
一个用于模拟三维细胞运动的数学模型框架及其在胶质母细胞瘤细胞迁移中的应用
M Scott,K Żychaluk,R N Bearon
M Scott
The collection of 3D cell tracking data from live images of micro-tissues is a recent innovation made possible due to advances in imaging techniques. As such there is increased interest in studying cell motility in 3D in vitro model systems...
Data assimilation of synthetic data as a novel strategy for predicting disease progression in alopecia areata [0.03%]
合成数据同化作为预测斑秃疾病进展的新策略
N G Cogan,Feng Bao,Ralf Paus et al.
N G Cogan et al.
The goal of patient-specific treatment of diseases requires a connection between clinical observations with models that are able to accurately predict the disease progression. Even when realistic models are available, it is very difficult t...
A structured model for COVID-19 spread: modelling age and healthcare inequities [0.03%]
一个结构化的新冠肺炎传播模型:模拟年龄和医疗资源的不均衡性
A James,M J Plank,R N Binny et al.
A James et al.
We use a stochastic branching process model, structured by age and level of healthcare access, to look at the heterogeneous spread of COVID-19 within a population. We examine the effect of control scenarios targeted at particular groups, su...
Addendum: Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling [0.03%]
附录:心房组织中肌细胞-纤维母细胞偶联的动作电位传播和阻滞模型
Peter Mortensen,Hao Gao,Godfrey Smith et al.
Peter Mortensen et al.
The analytical theory of our earlier study (Mortensen et al., 2021, Math. Med. Biol., 38, 106-131) is extended to address the outstanding cases of fibroblast barrier distribution and myocyte strait distribution. In particular, closed-form a...
Mathematical modelling of ageing acceleration of the human follicle due to oxidative stress and other factors [0.03%]
氧化应激等因素导致的人类卵泡加速衰老的数学模型研究
A M Portillo,C Peláez
A M Portillo
There is a gradual telomere shortening due to the inability of the replication machinery to copy the very ends of chromosomes. Additionally, other factors such as high levels of oxidation (free radicals or reactive oxygen species (ROS)), e....
Models for plasma kinetics during simultaneous therapeutic plasma exchange and extracorporeal membrane oxygenation [0.03%]
同时进行血浆置换和体外膜氧合的血浆动力学模型
Charles Puelz,Zach Danial,Jay S Raval et al.
Charles Puelz et al.
This paper focuses on the derivation and simulation of mathematical models describing new plasma fraction in blood for patients undergoing simultaneous extracorporeal membrane oxygenation and therapeutic plasma exchange. Models for plasma e...
A mathematical model for bleb regulation in zebrafish primordial germ cells [0.03%]
斑马鱼原始生殖细胞中血Blob调节的数学模型
Carolin Dirks,Paul Striewski,Benedikt Wirth et al.
Carolin Dirks et al.
Blebs are cell protrusions generated by local membrane-cortex detachments followed by expansion of the plasma membrane. Blebs are formed by some migrating cells, e.g. primordial germ cells of the zebrafish. While blebs occur randomly at eac...