Grace Bowman,Julie C Blackwood,Kathryn J Montovan et al.
Grace Bowman et al.
From 1999 to 2022, nearly 300,000 people died from overdoses involving prescription opioids. Commonly used for the management of acute post-surgical pain, prescription opioids remain a leading cause of opioid misuse and abuse. Among surgica...
Tuning Butterworth filter's parameters in SPECT reconstructions via kernel-based Bayesian optimization with a no-reference image evaluation metric [0.03%]
基于无参考图像评价标准的核泛函后验分布贝叶斯调优重建稀疏视图SPECT图像中的低剂量辐射区
Luca Pastrello,Diego Cecchin,Gabriele Santin et al.
Luca Pastrello et al.
In Single Photon Emission Computed Tomography (SPECT), the image reconstruction process involves many tunable parameters that have a significant impact on the quality of the resulting clinical images. Traditional image quality evaluation of...
Mechanical cell competition in a model of epithelial layer with size dependent proliferation [0.03%]
基于增殖依赖于细胞大小的上皮层模型中的机械式细胞竞争
Chenhao Zhang,Leo Clarke,Joseph Wilson et al.
Chenhao Zhang et al.
We investigate the competition of two cell types in an epithelial layer driven by differences in their mechanical properties. A simple one-dimensional model of a cell layer is represented as a chain of overdamped elastic springs with turnov...
The Effect of Cell Adhesion on the Interpretation of Scratch Assay Data: A Non-Local Model [0.03%]
细胞粘附对划痕愈合实验数据的影响研究：非局部动力学模型分析
Emine Atici Endes,Jonathan A Sherratt,Alf Gerisch
Emine Atici Endes
Scratch assays are affordable methods developed for sampling wound healing in a laboratory setting. Thanks to these assays, it is possible to investigate the dynamical structure of cell migration and proliferation, which play a central role...
Modeling the Effects of Combination Immunotherapy on Triple-Negative Breast Cancer in Syngeneic Mice from PET Imaging of CD4+ and CD8+ Cells [0.03%]
基于PET影像的CD4+和CD8+细胞对三阴性乳腺癌免疫联合治疗效果的影响机制研究模型
Dayton J Syme,Angelica A Davenport,Yun Lu et al.
Dayton J Syme et al.
We propose a system of ordinary differential equations to model the mouse immune response of two key immune cell types (CD4+ and CD8+ cells) to an established triple-negative breast cancer tumor while being treated with immunotherapy drugs ...
Stability Analysis and Quantification of Effects of Partial and Full Vaccination Using Fractional Order SVIR model [0.03%]
基于分数阶SVIR模型的偏种和全种疫苗稳定性和效果分析及量化研究
Abhay Srivastava,Nilam
Abhay Srivastava
An infectious disease such as COVID-19 posed a threat to public health worldwide due to its high infection rate and its further mutation into novel variants. Vaccination serves as a vital tool to interrupt its transmission cycle and far-rea...
Some results about the structural properties of the Wnt pathway, its steady states and its non-associative commutative algebra [0.03%]
Wnt信号通路的结构特性的若干结果及其稳态和非结合交换代数的一些性质研究
Quentin Vanhaelen
Quentin Vanhaelen
We consider a reaction network of the Wnt pathway endowed with mass-action kinetics. Using concepts in the theory of robustness and stability within Chemical Reaction Network Theory and advances in decomposing reaction networks, we perform ...
Impact of biosecurity and immunological memory in curtailing ratio-dependent transmission of anthrax in livestock [0.03%]
生物安全和免疫记忆在遏制畜牧业传染性炭疽中的作用
Piu Samui,Sima Mandal,Jayanta Mondal
Piu Samui
Delineating the dynamics of highly lethal anthrax disease in a biosecured livestock farm and impact of anthrax vaccination is presented through a modified deterministic SIRBV model incorporating nonlinear ratio-dependent disease transmissio...
Estimating transmission parameters and the reproduction number: COVID-19 in Sri Lanka as a case study [0.03%]
估计传播参数和再生数：斯里兰卡新冠肺炎疫情案例研究
Dinesh B Ekanayake,Iduruwage Harsha Premarathna,Elizabeth Hansen
Dinesh B Ekanayake
The study of the dynamics of an infectious disease is fundamental to understanding its community spread. These include obtaining estimates for transmission rates, recovery rates, and the average number of secondary cases per infectious case...
Effects of reduced temperature on oxygen transport from capillaries to brain tissue [0.03%]
低温对从毛细血管向脑组织供氧的影响
Samikshaa Natarajan,Timothy W Secomb
Samikshaa Natarajan
The normal function of the brain depends on adequate oxygen supply. Oxygen deprivation (hypoxia) can result in irreversible damage to neurons within minutes. Cooling (hypothermia) of brain tissue can reduce the rate of damage, and is used i...