A systematic evaluation of the influence of macrophage phenotype descriptions on inflammatory dynamics [0.03%]
巨噬细胞表型描述对炎症动力学影响的系统评价
Suliman Almansour,Joanne L Dunster,Jonathan J Crofts et al.
Suliman Almansour et al.
Macrophages play a wide range of roles in resolving the inflammatory damage that underlies many medical conditions and have the ability to adopt different phenotypes in response to different environmental stimuli. Categorising macrophage ph...
Impact of climate change on vegetation patterns in Altay Prefecture, China [0.03%]
气候变化对我国阿尔泰地区植被格局的影响
Li Li,Yi-Zhi Pang,Gui-Quan Sun et al.
Li Li et al.
Altay Prefecture, a typical arid region in northwestern China, has experienced the climate transition from warming-drying to warming-wetting since 1980s and has attracted widespread attention. Nonetheless, it is still unclear how climate ch...
Dosage optimization for reducing tumor burden using a phenotype-structured population model with a drug-resistance continuum [0.03%]
利用表型结构种群模型优化药物剂量以减少肿瘤负荷中的药物抗性连续体研究
Lifeng Han,Osman N Yogurtcu,Marisabel Rodriguez Messan et al.
Lifeng Han et al.
Drug resistance is a significant obstacle to effective cancer treatment. To gain insights into how drug resistance develops, we adopted a concept called fitness landscape and employed a phenotype-structured population model by fitting to a ...
Asymptotic properties of the Lotka-Volterra competition and mutualism model under stochastic perturbations [0.03%]
随机扰动下Lotka-Volterra竞争和互惠模型的渐近性态
Leonid Shaikhet,Andrei Korobeinikov
Leonid Shaikhet
Stochastically perturbed models, where the white noise type stochastic perturbations are proportional to the current system state, the most realistically describe real-life biosystems. However, such models essentially have no equilibrium st...
Laurens Bogaardt,Anoukh van Giessen,H Susan J Picavet et al.
Laurens Bogaardt et al.
A risk factor model of body mass index (BMI) is an important building block of health simulations aimed at estimating government policy effects with regard to overweight and obesity. We created a model that generates representative populati...
Pattern formation and travelling waves in a multiphase moving boundary model of tumour growth [0.03%]
肿瘤生长多相变边界模型中的图案形成和行波现象
Jacob M Jepson,Reuben D O&#x;Dea,John Billingham et al.
Jacob M Jepson et al.
We employ the multiphase, moving boundary model of Byrne et al. (2003, Appl. Math. Lett., 16, 567-573) that describes the evolution of a motile, viscous tumour cell phase and an inviscid extracellular liquid phase. This model comprises two ...
Effects of vaccination on the two-strain transmission dynamics of COVID-19: Dougherty County, Georgia, USA, as a case study [0.03%]
疫苗接种对COVID-19双毒株传播动力学的影响——以美国佐治亚州多尔特尼县为例研究
Buddhi Pantha,Jemal Mohammed-Awel,Naveen K Vaidya
Buddhi Pantha
The emergence of multiple strains of SARS-COV-2 has made it complicated to predict and control the COVID-19 pandemic. Although some vaccines have been effective in reducing the severity of the disease, these vaccines are designed for a spec...
Which airways should we treat? Structure-function relationships and estimation of the singular input modes from the forward model alone [0.03%]
哪些气道需要被处理？结构-功能关系以及仅从前向模型估计奇异输入模式的方法
Graham M Donovan
Graham M Donovan
Structure-function relationships occur throughout the sciences. Motivated by optimization of such systems, we develop a framework for estimating the input modes from the singular value decomposition from the action of the forward operator a...
Roumen Anguelov,G Manjunath,Avulundiah E Phiri et al.
Roumen Anguelov et al.
Inhibiting a signalling pathway concerns controlling the cellular processes of a cancer cell's viability, cell division and death. Assay protocols created to see if the molecular structures of the drugs being tested have the desired inhibit...
Hannah J Pybus,Reuben D O&#x;Dea,Bindi S Brook
Hannah J Pybus
Excessive activation of the regulatory cytokine transforming growth factor $/beta $ (TGF-$/beta $) via contraction of airway smooth muscle (ASM) is associated with the development of asthma. In this study, we develop an ordinary differentia...