Beyond SIRD models: a novel dynamic model for epidemics, relating infected with entries to health care units and application for identification and restraining policy [0.03%]
超越SIRD模型:一种新的流行病动态模型,结合感染与进入医疗单位的关系及应用以识别和限制政策
Christos Tsiliyannis
Christos Tsiliyannis
Epidemic models of susceptibles, exposed, infected, recovered and deceased (SΕIRD) presume homogeneity, constant rates and fixed, bilinear structure. They produce short-range, single-peak responses, hardly attained under restrictive measur...
Inference on an interacting diffusion system with application to in vitro glioblastoma migration (publication template) [0.03%]
应用于体外胶质母细胞瘤迁移的相互作用扩散系统的推断(出版模板)
Gustav Lindwall,Philip Gerlee
Gustav Lindwall
Glioblastoma multiforme is a highly aggressive form of brain cancer, with a median survival time for diagnosed patients of 15 months. Treatment of this cancer is typically a combination of radiation, chemotherapy and surgical removal of the...
Henri Berestycki,Jean-Michel Roquejoffre,Luca Rossi
Henri Berestycki
The goal of this work is to understand and quantify how a line with nonlocal diffusion given by an integral enhances a reaction-diffusion process occurring in the surrounding plane. This is part of a long term programme where we aim at mode...
Assessing marginal effects of non-pharmaceutical interventions on the transmission of SARS-CoV-2 across Africa: a hybrid modeling study [0.03%]
非洲非药物干预措施对SARS-CoV-2传播边缘效应的评估:混合模型研究
Yvette Montcho,Sidoine Dako,Valère Kolawole Salako et al.
Yvette Montcho et al.
Since 2019, a new strain of coronavirus has challenged global health systems. Due its fragile healthcare systems, Africa was predicted to be the most affected continent. However, past experiences of African countries with epidemics and othe...
François Hamel,Mingmin Zhangy
François Hamel
This paper is concerned with the existence of transition fronts for a one-dimensional two patch model with KPP reaction terms. Density and flux conditions are imposed at the interface between the two patches. We first construct a pair of su...
Saddam Hussain,Moitri Sen,Vitaly Volpert
Saddam Hussain
Viral infection develops in the organism due to virus replication inside infected cells and its transmission from infected to uninfected cells through the extracellular matrix or cell junctions. In this work, we model infection spreading in...
Anton Vrdoljak,Damir Vukičević
Anton Vrdoljak
Experimental and theoretical properties of amino acids as building blocks of peptides and proteins have been extensively researched. Each such method assigns a number to each amino acid, and one such assignment is called amino-acid scale. T...
Phenotype divergence and cooperation in isogenic multicellularity and in cancer [0.03%]
同基因多细胞生物及癌细胞的表型差异和合作现象
Frank Ernesto Alvarez,Jean Clairambault
Frank Ernesto Alvarez
We discuss the mathematical modelling of two of the main mechanisms that pushed forward the emergence of multicellularity: phenotype divergence in cell differentiation and between-cell cooperation. In line with the atavistic theory of cance...
Mathematical modelling, selection and hierarchical inference to determine the minimal dose in IFNα therapy against myeloproliferative neoplasms [0.03%]
数学建模、选择和分层推理确定干扰素α治疗髓系肿瘤的最小剂量
Gurvan Hermange,William Vainchenker,Isabelle Plo et al.
Gurvan Hermange et al.
Myeloproliferative neoplasms (MPN) are blood cancers that appear after acquiring a driver mutation in a hematopoietic stem cell. These hematological malignancies result in the overproduction of mature blood cells and, if not treated, induce...
A systematic evaluation of the influence of macrophage phenotype descriptions on inflammatory dynamics [0.03%]
巨噬细胞表型描述对炎症动力学影响的系统评价
Suliman Almansour,Joanne L Dunster,Jonathan J Crofts et al.
Suliman Almansour et al.
Macrophages play a wide range of roles in resolving the inflammatory damage that underlies many medical conditions and have the ability to adopt different phenotypes in response to different environmental stimuli. Categorising macrophage ph...