HeMiTo-dynamics: a characterisation of mammalian prion toxicity using non-dimensionalisation, linear stability and perturbation analyses [0.03%]
非 dimensionalisation、线性稳定和扰动分析在利用小鼠模型研究人致病型朊病毒毒性的特征中的应用
Johannes G Borgqvist,Christoffer Gretarsson Alexandersen
Johannes G Borgqvist
Prion-like proteins play crucial parts in biological processes in organisms ranging from yeast to humans. For instance, many neurodegenerative diseases are believed to be caused by the production of prion-like proteins in neural tissue. As ...
On the large time behaviour of the solutions of an evolutionary-epidemic system with spatial dispersal [0.03%]
具有空间分散的传染病动力学系统的长时间渐近行为分析
A Ducrot,D Manceau,A Sylla
A Ducrot
This paper investigates some properties of the large time behaviour of the solutions of a spatially distributed system of equations modelling the evolutionary epidemiology of a plant-pathogen system. The model takes into account the phenoty...
Polymer-interface-tissue model to estimate leachable release from medical devices [0.03%]
一种用于估算医疗器械释放出的可提取物的聚合物-界面-组织模型
Martin L Tanaka,David M Saylor,Robert M Elder
Martin L Tanaka
The ability to predict clinically relevant exposure to potentially hazardous compounds that can leach from polymeric components can help reduce testing needed to evaluate the biocompatibility of medical devices. In this manuscript, we compa...
Effect of diffusivity of amyloid beta monomers on the formation of senile plaques [0.03%]
淀粉样β单体扩散性对老年斑形成的影响
Andrey V Kuznetsov
Andrey V Kuznetsov
Alzheimer's disease (AD) presents a perplexing question: why does its development span decades, even though individual amyloid beta (Aβ) deposits (senile plaques) can form rapidly in as little as 24 hours, as recent publications suggest? T...
Avishek Mukherjee,Navid Mohammad Mirzaei,Pak-Wing Fok
Avishek Mukherjee
This paper investigates intimal growth in arteries, induced by hemodynamical shear stress, through finite element simulation using the FEniCS computational environment. In our model, the growth of the intima depends on cross-section geometr...
Modelling the influence of vitamin D and probiotic supplementation on the microbiome and immune response [0.03%]
维生素D和益生菌补充剂对微生物组和免疫反应影响的建模分析
S J Franks,J L Dunster,S R Carding et al.
S J Franks et al.
The intestinal microbiota play a critical role in human health and disease, maintaining metabolic and immune/inflammatory health, synthesizing essential vitamins and amino acids and maintaining intestinal barrier integrity. The aim of this ...
Oscillations in a tumor-immune system interaction model with immune response delay [0.03%]
具有免疫响应时滞的肿瘤免疫系统相互作用模型中的振荡现象
Zhaoxuan Huo,Jicai Huang,Yang Kuang et al.
Zhaoxuan Huo et al.
In this paper we consider a tumor-immune system interaction model with immune response delay, in which a nonmonotonic function is used to describe immune response to the tumor burden and a time delay is used to represent the time for the im...
Calibration and comparison of SIR, SEIR/SLIR and SLAIR models for influenza dynamics: insights from the 2016-2017 season in the Valencian Community, Spain [0.03%]
西班牙瓦伦西亚自治区2016-2017年流感流行动态的SIR，SEIR/SLIR和SLAIR模型的校准与比较：见解
Rim Adenane,Carlos Andreu-Vilarroig,Florin Avram et al.
Rim Adenane et al.
Influenza and influenza-like illnesses pose significant challenges to healthcare systems globally. Mathematical models play a crucial role in understanding their dynamics, calibrating them to specific scenarios and making projections about ...
Forecasting the changes between endemic and epidemic phases of a contagious disease, with the example of COVID-19 [0.03%]
以新冠肺炎为例预测传染病地方性流行和大流行阶段的转换
Jacques Demongeot,Pierre Magal,Kayode Oshinubi
Jacques Demongeot
Background: Predicting the endemic/epidemic transition during the temporal evolution of a contagious disease. Methods: Indicators for d...