Molecular analysis of lipid uptake- and necroptosis-associated factor expression in vitrified-warmed mouse oocytes [0.03%]
玻璃化冷冻-解冻小鼠卵母细胞脂质摄取和坏死凋亡相关因子的分子分析
Da-Eun Um,Hyejin Shin,Dayoung Park et al.
Da-Eun Um et al.
Background: We had previously demonstrated that vitrification reduces the levels of certain phospholipid classes, and that oocytes from aged mice show a similar lipidome alteration, even without vitrification. In the curr...
Does body mass index impact assisted reproductive technology treatment outcomes in gestational carriers [0.03%]
体质指数对代孕者辅助生殖技术治疗结局的影响分析
Noga Fuchs Weizman,Miranda K Defer,Janice Montbriand et al.
Noga Fuchs Weizman et al.
Background: The purpose of this study was to assess whether increased body mass index (BMI) negatively affects assisted reproductive technology (ART) outcomes among gestational carriers. ...
Clinical, hormonal and genetic characteristics of androgen insensitivity syndrome in 39 Chinese patients [0.03%]
中国39例雄激素不敏感综合征患者的临床、内分泌及遗传特征分析
Qingxu Liu,Xiaoqin Yin,Pin Li
Qingxu Liu
Background: Abnormal androgen receptor (AR) genes can cause androgen insensitivity syndrome (AIS), and AIS can be classified into complete androgen insensitivity syndrome (CAIS), partial androgen insensitivity syndrome (P...
Decreased brain and muscle ARNT-like protein 1 expression mediated the contribution of hyperandrogenism to insulin resistance in polycystic ovary syndrome [0.03%]
高雄激素通过降低脑和肌肉ARNT样蛋白1表达促进多囊卵巢综合征胰岛素抵抗形成
Junyu Zhai,Shang Li,Min Hu et al.
Junyu Zhai et al.
Background: The interface between environmental risk factors and genetic factors could contribute to the pathogenesis of hyperandrogenism and insulin resistance in polycystic ovary syndrome (PCOS); however, the underlying...
Pavel Zagadailov,David B Seifer,He Shan et al.
Pavel Zagadailov et al.
Background: Assisted reproductive technology (ART) insurance mandates resulted in improved access to infertility treatments like intracytoplasmic sperm injection (ICSI). Our objective was to examine whether ART insurance ...
hsa-miR-100-5p, an overexpressed miRNA in human ovarian endometriotic stromal cells, promotes invasion through attenuation of SMARCD1 expression [0.03%]
人卵巢子宫内膜异位病灶成纤维细胞中过度表达的hsa-miR-100-5p通过抑制SMARCD1的表达促进侵袭作用
Kanetoshi Takebayashi,Kaei Nasu,Mamiko Okamoto et al.
Kanetoshi Takebayashi et al.
Background: A number of microRNAs are aberrantly expressed in endometriosis and are involved in its pathogenesis. Our previous study demonstrated that has-miR-100-5p expression is enhanced in human endometriotic cyst stro...
Disruption of androgen signaling during puberty affects Notch pathway in rat seminiferous epithelium [0.03%]
青春期干扰雄激素信号影响大鼠生精上皮 notch 途径
Alicja Kamińska,Sylwia Marek,Laura Pardyak et al.
Alicja Kamińska et al.
Background: Onset of spermatogenesis at puberty is critically dependent on the activity of hypothalamic-pituitary-gonadal axis and testosterone production by Leydig cells. The aim of this study was to examine whether acti...
Effect of cold stress on ovarian & uterine microcirculation in rats and the role of endothelin system [0.03%]
冷应激对大鼠卵巢和子宫微循环的影响及内皮素系统的作用
Di Wang,Xiumei Cheng,Huimin Fang et al.
Di Wang et al.
Background: Cold, an environmental factor, induces many reproductive diseases. It is known that endothelin (ET) is a potent vasoconstrictor, and cold stress can increase the expression of ET and its receptors. The cold st...
Performing ICSI within 4 hours after denudation optimizes clinical outcomes in ICSI cycles [0.03%]
体外受精-卵胞浆内单精子注射去核后4小时内进行卵胞浆内单精子注射可优化临床结局
Yini Zhang,Yongzhuang Ma,Zishui Fang et al.
Yini Zhang et al.
Background: The study aimed to investigate whether and how general and partial time intervals between processes, from human chorionic gonadotrophin (HCG) trigger to intracytoplasmic sperm injection (ICSI), affected the la...
A prospective, single-centre, single-arm, open label study of the long term use of a gonadotropin releasing hormone agonist (Triptorelin SR, 11.25 mg) in combination with Tibolone add-back therapy in the management of chronic cyclical pelvic pain [0.03%]
一项有关促性腺激素释放激素激动剂（Trimaxolene SR，11.25毫克）联合戊酸雌二醇替代疗法治疗慢性盆腔痛的前瞻性、单中心、开放标记试验
Sallwa M Alshehre,Sheila Duffy,Georgina Jones et al.
Sallwa M Alshehre et al.
Background: Chronic cyclic pelvic pain (CCPP) affects women's quality of life and pituitary downregulation is often used for symptomatic relief. However, prolonged suppression of ovarian function is associated with menopa...