Assessing the female urogenital-rectal axis microbiome: focus on endometriosis and recurrent implantation failure [0.03%]
女性泌尿生殖道-直肠轴微生物组的评估：关注子宫内膜异位症和反复种植失败
Bárbara A Folch,Inmaculada Pérez-Prieto,Eduardo Salas-Espejo et al.
Bárbara A Folch et al.
Background: Emerging evidence suggests microbial dysbiosis may contribute to gynaecological pathologies, including endometriosis and recurrent implantation failure (RIF). The vaginal microbiome is well-characterised, with...
Hongbo Wu,Zhao Zhang,Qianyi Huang et al.
Hongbo Wu et al.
Ovarian aging is characterized by the progressive depletion of the follicular reserve and deterioration of reproductive endocrine function, yet its cellular basis has been disproportionately attributed to oocyte and granulosa cell decline. ...
The impact of fresh versus cryopreserved testicular sperm on in-vitro fertilization outcomes in couples with elevated sperm DNA fragmentation: a retrospective cohort study [0.03%]
新鲜与冷冻睾丸精子对高精子DNA碎片化夫妇体外受精结局影响的队列研究
Dana R Siegel,Laura K Kaizer,Mary D Sammel et al.
Dana R Siegel et al.
Background: Elevated sperm DNA fragmentation (SDF) is associated with male factor infertility, recurrent pregnancy loss, and poor reproductive outcomes. An option for management includes the utilization of testicular sper...
Injury and recovery patterns of the blood-testis barrier and spermatogenic function in a surgical unilateral cryptorchidism model in rats [0.03%]
手术单侧隐睾大鼠模型中血睾屏障损伤及生精功能恢复规律研究
Yan He,Run-Long Wang,Li-Peng Li et al.
Yan He et al.
Background: Cryptorchidism is one of the most common congenital disorders of the pediatric urogenital system. In addition to regulating the passage of substances into and out of the seminiferous epithelium, the blood-test...
Methods to assess trustworthiness of data from peer-reviewed, published randomised controlled trials [0.03%]
评估同行评审的随机对照试验的数据可靠性的方法
Lyle C Gurrin,Nicole Au,Jeremy Nielsen et al.
Lyle C Gurrin et al.
Background: Untrustworthy randomised controlled trials (RCTs) and other study types are an increasingly recognised problem in health and medical research. Assessing and responding to this problem is essential for ensuring...
Transcriptome analysis of follicular granulosa cells in young women with diminished ovarian reserve [0.03%]
卵泡颗粒细胞的转录组分析在年轻女性中卵巢储备功能下降的影响
Peizhe Tian,Yanfang Lu,Lei Zhang et al.
Peizhe Tian et al.
Background: Diminished ovarian reserve (DOR) is defined as the decline in both quantity and quality of oocytes in the ovarian cortex. In recent years, DOR has shown an increasing trend among young women. However, the spec...
An analysis of the outcome of 2,443 women applying to be donors at a commercial egg bank in the USA [0.03%]
一项关于在美国一家商业卵子库申请捐卵的2443名女性的结果分析
Allan A Pacey,Emilie Lassen,Guido Pennings et al.
Allan A Pacey et al.
Background: Donated eggs are essential for a range of Medically Assisted Reproduction (MAR) procedures, but relatively little has been written about how donors are recruited. This study examined egg donor recruitment proc...
Immune escape in endometriosis: mechanisms, reprogramming strategies, and precision interventions [0.03%]
子宫内膜异位症的免疫逃逸：机制、重编程策略和精准干预措施
Huiting Chen,Meng Zhang,Weidong Fei et al.
Huiting Chen et al.
Background: Endometriosis is a prevalent estrogen-dependent inflammatory disorder that compromises women's quality of life and fertility through chronic pelvic pain, inflammation, and reproductive dysfunction. Current cli...
Effect of uterine peristalsis at the time of embryo transfer on the outcomes of IVF cycles: a prospective cohort study [0.03%]
子宫收缩对体外受精周期胚胎移植结果的影响：一项前瞻性队列研究
Karim S Abdallah,Kamal M Zahran,Mahmoud A Othman et al.
Karim S Abdallah et al.
Background: It has recently been discovered that one of the key elements influencing endometrial receptivity is uterine peristalsis. This was a prospective cohort study aiming to assess uterine peristalsis at the time of ...
The endometriosis-adenomyosis spectrum: shared pathophysiology and microenvironment-driven disease divergence [0.03%]
子宫内膜异位症-腺肌病谱系：共同的病理生理和微环境驱动的疾病差异性
Hiroshi Kobayashi
Hiroshi Kobayashi
Endometriosis and adenomyosis are common gynecologic disorders associated with dysmenorrhea, chronic pelvic pain, and infertility. Although they share several molecular features, the mechanisms by which endometrium-derived tissues develop d...