Obesity has a detrimental impact on temporal decline of sperm quality in normospermic patients: insights from a cross-sectional study of 2,430 patients over 14 years [0.03%]
肥胖对正常精子质量的时序性下降有负面影响——来自14年2430例患者横断面研究的新见解
Giorgio Ivan Russo,Maria Giovanna Asmundo,Andrea Cocci et al.
Giorgio Ivan Russo et al.
Background: Obesity is a known factor influencing sperm quality through hormonal imbalances and oxidative stress, contributing to male infertility.This study examines the association between obesity and temporal declines ...
Dysregulated autophagy in endometriosis: molecular mechanisms, controversies, and clinical implications [0.03%]
子宫内膜异位症中自噬失调：分子机制、争议和临床意义
Clara Tellez-Quijorna,Ainhoa Juan-Lopez,Nuria Eritja et al.
Clara Tellez-Quijorna et al.
Endometriosis is one of the most common gynecological diseases in women and is still one of the most understudied diseases, affecting the daily lives of patients. Although the exact cause of this condition remains unclear, autophagy has bee...
Feasibility and efficacy of random-start progestin-primed ovarian stimulation: a multicenter pilot randomized controlled trial in oocyte donation [0.03%]
随机启动孕酮触发方案在卵子捐赠中可行性及有效性的多中心试点随机对照研究
Emmanuelle Mathieu d&#x;Argent,Anne Guivarc&#x;h-Leveque,Sophie Catteau-Jonard et al.
Emmanuelle Mathieu d&#x;Argent et al.
Glucose and pyruvate differentially modulate metabolic and redox dynamics during capacitation to enable fertilization competence in mouse sperm [0.03%]
葡萄糖和乳酸通过调控精子获能过程中的代谢和氧化还原稳态差异性地影响小鼠精子受精能力
Jael D Herzfeld,Lucas N González,Candela Senosiain et al.
Jael D Herzfeld et al.
Male infertility remains prevalent, with many cases unexplained due to limited understanding of sperm physiology. Capacitation, the process by which ejaculated sperm acquire fertilizing ability within the female reproductive tract, requires...
The "double-edged sword" effect of non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of endometriosis (EMS) [0.03%]
非甾体抗炎药(NSAIDs)治疗子宫内膜异位症(EMS)的“双刃剑”效应
Zunlin Shi,Zhi Li,Yirou Li et al.
Zunlin Shi et al.
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to alleviate pain associated with endometriosis (EMS), yet the impact of their long-term use on disease progression remains unclear. This study ...
Microbiome analysis of the cystic fluid in ovarian endometrioma: new avenues for the prevention, diagnosis, and treatment of the disease [0.03%]
卵巢子宫内膜异位囊肿的微生态分析：疾病的预防、诊断及治疗新策略
Sai-Hua Zheng,Xian-Qian Chen,Zhen-Hong Wang et al.
Sai-Hua Zheng et al.
Objective: This study aimed to investigate the microbiome profile in the cystic fluid of ovarian endometrioma and explore its association with the microbial communities present in the lower and upper reproductive tracts. ...
Effect of grafting site on reproductive outcomes following cryopreserved ovarian tissue transplantation: a meta-analysis and systematic review [0.03%]
卵巢冷冻组织移植供体部位对生殖结局影响的系统综述和meta分析
Ziyu Li,Yanru Hou,Yifei Cheng et al.
Ziyu Li et al.
Background: More than 500 patients have received cryopreserved ovarian tissue transplantation (OTT) worldwide, resulting in over 200 live births. Although guidelines recognize OTT as an effective fertility preservation me...
Women with endometriosis who undergo IVF: a contemporary review of therapeutic strategies for successful outcomes [0.03%]
子宫内膜异位症患者进行体外受精：获得成功结局的治疗方法综述
Alexander M Kotlyar,David B Seifer
Alexander M Kotlyar
Congenital anomalies after first-trimester dydrogesterone therapy during in vitro fertilization [0.03%]
体外受精早期妊娠阶段使用地屈孕酮后的先天畸形发生率
Wan Yang,Lin Zeng,Lixue Chen et al.
Wan Yang et al.
Genetic and epigenetic insights into non-obstructive azoospermia: mechanisms, biomarkers, and clinical perspectives [0.03%]
非梗阻性无精子症的遗传和表观遗传学见解：机制、生物标志物和临床视角
Xiaojie Wang,Linhang Nie,Zhidan Hong et al.
Xiaojie Wang et al.
Non-obstructive azoospermia (NOA) is one of the most severe manifestations of male infertility, accounting for up to 70% of azoospermic cases and affecting approximately 1% of the male population. Advances in genomics and epigenetics have t...