Depression, anxiety, and stress impair sperm quality via dysregulation of the mitochondrial PDK-PDC axis [0.03%]
抑郁、焦虑和压力通过调节线粒体PDK-PDC轴紊乱而损害精子质量
Wang Wang,Wang Qikai,Wang Zilin et al.
Wang Wang et al.
Male infertility, a significant global public health challenge, arises from multifactorial interactions involving genetic, metabolic, and psychological factors. While psychological stress (depression/anxiety/stress, DAS) is increasingly lin...
Integrating impact of FSH isoforms, androgens and inhibin-B on follicular development based on a two-phase model of the follicular phase [0.03%]
基于卵泡期两阶段模型的FSH异构体、雄激素和抑制素B对卵泡发育综合影响的整合研究
Claus Yding Andersen
Claus Yding Andersen
Hydrogen sulfide in placental development and pregnancy disorders: mechanisms, therapeutic potential, and translational challenges [0.03%]
氢 sulfide在胎盘发育和妊娠紊乱中的作用：机制、治疗潜力及转化挑战
Lijia Du,Rui Zheng,Weina Ren et al.
Lijia Du et al.
The placenta plays a crucial role in maintaining pregnancy stability, regulating fetal growth, and facilitating maternal-fetal exchange. Its proper development relies on placental vasculogenesis and angiogenesis, along with adaptive remodel...
Structural and hormonal changes in the ovaries of women with polycystic ovary syndrome and healthy controls: a 13-year prospective study in an unselected population [0.03%]
多囊卵巢综合征和健康对照组女性的卵巢结构和激素变化：未经筛选人群中的13年前瞻性研究
Nevda Ceren Sonu,Seren Aksun,Gurkan Bozdag et al.
Nevda Ceren Sonu et al.
Background: This study investigates whether ovarian structural and hormonal changes over a 13-year period differ between women diagnosed with polycystic ovary syndrome (PCOS) and healthy controls within an unselected popu...
Role of hyaluronan in endometrial receptivity: key insights for implantation and reproductive success [0.03%]
透明质酸在子宫内膜接受性中的作用：植入及生殖成功的关键见解
Eva Krivakova,Michal Michna,Nicole Fabianova et al.
Eva Krivakova et al.
Infertility affects millions worldwide, and implantation failure remains a critical barrier in assisted reproduction. Endometrial receptivity, a fundamental prerequisite for successful implantation, involves precise regulation of extracellu...
Alteration of the follicular fluid amino acid profile reveals the important roles of several amino acids in embryo quality in patients with polycystic ovary syndrome [0.03%]
卵泡液氨基酸谱的改变揭示了几个氨基酸在多囊卵巢综合征患者胚胎质量中的重要作用
Li Yu,Wei Cai,Chen Wang et al.
Li Yu et al.
Background: Polycystic ovary syndrome (PCOS) is widely acknowledged as the prevailing reproductive endocrine disorder accompanied by numerous metabolic dysfunctions. However, there has been a lack of systematic examinatio...
FTO regulates testosterone secretion in Leydig cells: insights into the role of m6A modifications and the therapeutic potential of hCG [0.03%]
FTO调节莱迪希细胞睾丸素分泌：m6A修饰的作用及人绒毛膜促性腺激素的治疗潜力的新见解
Chenglu Wang,Kebing Yang,Fang Gao et al.
Chenglu Wang et al.
Background: Testosterone plays a pivotal role in male reproductive health and is synthesized primarily by Leydig cells (LCs) in the testes. Alterations in testosterone levels can lead to sexual dysfunction, reduced fertil...
Systemic impacts of diabetes on spermatogenesis and intervention strategies: multilayered mechanism analysis and cutting-edge therapeutic approaches [0.03%]
糖尿病对精子发生的影响及干预策略：多层机制分析与前沿治疗手段
Jinyue Rong,Xu Leng,Kun Jiang et al.
Jinyue Rong et al.
Diabetes mellitus (DM), a chronic metabolic disease with a high global prevalence, has increasingly been recognized for its adverse effects on the male reproductive system, particularly spermatogenesis. This review systematically summarizes...
Elevated serum estradiol levels on embryo transfer day predict higher pregnancy success in HRT-FET cycles [0.03%]
补佳乐周期冻胚移植日血清雌二醇水平的个体化指导及临床结局分析
Maryam Azizi Kutenaee,Fatemeh Bahmani,Farzaneh Fesahat et al.
Maryam Azizi Kutenaee et al.
Objective: To investigate the association between serum estradiol (E2) levels on the day of embryo transfer and clinical pregnancy outcomes in hormonally prepared frozen–thawed embryo transfer (HRT-FET) cycles with optim...
Insulin resistance as a determinant of fertilization efficiency in polycystic ovary syndrome patients undergoing IVF/ICSI: a retrospective cohort study [0.03%]
胰岛素抵抗在多囊卵巢综合征患者体外受精/卵胞浆内单精子显微注射中的促孕作用：一项回顾性队列研究
Ruiteng Zhang,Xuejin Wang,Meilan Mo et al.
Ruiteng Zhang et al.
Background: This retrospective cohort study aimed to evaluate the impact of insulin resistance (IR) on clinical outcomes in polycystic ovary syndrome (PCOS) patients undergoing in vitro fertilization (IVF) or intracytopla...