Is oral dydrogesterone equivalent to vaginal micronized progesterone for luteal phase support in women receiving oocyte donation? [0.03%]
口服dydrogesterone与阴道给药微粉化孕酮作为卵子捐赠妇女黄体期支持的补充疗法是否等效？
Margaux Lorillon,Geoffroy Robin,Laura Keller et al.
Margaux Lorillon et al.
Research question: To determine whether the use of oral dydrogesterone (DYD) in luteal phase support (LPS) during an artificial cycle provides equivalent clinical and ongoing pregnancy, delivery and miscarriage rates as m...
Observational Study
Reproductive biology and endocrinology : RB&E. 2024 Dec 5;22(1):154. DOI:10.1186/s12958-024-01322-7 2024
Pre-pregnancy LDL/HDL and total Cholesterol/HDL ratios are strong predictors of gestational diabetes mellitus in women undergoing assisted reproductive technologies [0.03%]
辅助生殖技术受孕女性妊娠期糖尿病的预测指标：孕前LDL/HDL和总胆固醇/HDLC值比率较强
Yvonne Liu,Johann-Georg Hocher,Shujuan Ma et al.
Yvonne Liu et al.
Background & objective: To analyze whether there is an association between pre-pregnancy lipid parameters and gestational diabetes mellitus (GDM) in women undergoing assisted reproductive technologies (ART), a group espec...
Observational Study
Reproductive biology and endocrinology : RB&E. 2024 Dec 5;22(1):155. DOI:10.1186/s12958-024-01320-9 2024
Whole-exome sequencing and Drosophila modelling reveal mutated genes and pathways contributing to human ovarian failure [0.03%]
全外显子组测序和果蝇模型揭示了与人类卵巢衰竭相关的突变基因及信号通路
Ismael Henarejos-Castillo,Francisco José Sanz,Cristina Solana-Manrique et al.
Ismael Henarejos-Castillo et al.
Background: Ovarian failure (OF) is a multifactorial, complex disease presented by up to 1% of women under 40 years of age. Despite 90% of patients being diagnosed with idiopathic OF, the underlying molecular mechanisms r...
Age-related uterine changes and its association with poor reproductive outcomes: a systematic review and meta-analysis [0.03%]
与不良生殖结局相关的年龄相关子宫变化：系统评价和 Meta 分析
Diana Marti-Garcia,Asunta Martinez-Martinez,Francisco Jose Sanz et al.
Diana Marti-Garcia et al.
Background: The decline in women's fertility becomes clinically relevant between 35-40 years old, when there is insufficient ovarian activity, and it becomes more difficult to achieve pregnancy naturally and through artif...
Integrated bioinformatics analysis reveals that CCBP2 and GPR87 are new GPCR-associated biomarkers for preeclampsia [0.03%]
整合生物信息学分析发现CCBP2和GPR87是子痫前期的新的受体相关生物标志物
Jie Li,Meng-Meng Chen,Bingqiang Zhang et al.
Jie Li et al.
Background: Preeclampsia (PE) is a multifaceted pregnancy syndrome marked by multiple system involvement and a significant contributor to maternal mortality. This condition is characterized by a critical lack of early dia...
Dendritic cells under the control of the preimplantation embryo secretome: an in vitro study [0.03%]
受精前胚胎分泌组控制的树突状细胞：一项体外研究
Christiana Kyvelidou,Sofia Haselrieder,Maria von Gierke et al.
Christiana Kyvelidou et al.
Objective: To study the crosstalk between maternal immune cells and the developing embryo by investigating the immunogenic properties of human blastocyst spent media (SM) on dendritic cells. ...
Effect of serum uric acid level on reproductive outcome in women without polycystic ovary syndrome undergoing in vitro fertilization [0.03%]
无多囊卵巢综合征女性尿酸水平对体外受精助孕结局的影响
Leizhen Xia,Lu Fan,Jialyu Huang et al.
Leizhen Xia et al.
Background: Prior research showed that elevated serum uric acid (SUA) levels in women with polycystic ovary syndrome (PCOS) before in vitro fertilization or intracytoplasmic sperm injection (IVF/ICSI) treatment can lead t...
Association of insulin resistance surrogate indices and erectile dysfunction: a systematic review and meta-analysis [0.03%]
糖耐量减退与勃起功能障碍关联的系统评价和meta分析
Sayeh Jalali,Negar Zareshahi,Amir Hossein Behnoush et al.
Sayeh Jalali et al.
Background: Erectile dysfunction (ED) has been linked to insulin resistance (IR), with various surrogate indices being used to assess this association. This systematic review and meta-analysis aimed to evaluate the relati...
Levonorgestrel at emergency contraception dose has no effect on ciliary beat frequency and muscular contraction of the human fallopian tube: an in vitro experimental study [0.03%]
左炔诺孕酮紧急避孕剂量对人输卵管纤毛摆动频率及管壁收缩功能无影响：体外实验研究
Raymond Hang Wun Li,Su-Bin Liao,William Shu Biu Yeung et al.
Raymond Hang Wun Li et al.
Background: Levonorgestrel (LNG) acts as an emergency contraceptive mainly by inhibiting or postponing ovulation. We carried out this study to investigate whether LNG at concentration relevant for emergency contraception ...
Analysis of single-cell RNA sequencing in human oocytes with diminished ovarian reserve uncovers mitochondrial dysregulation and translation deficiency [0.03%]
单细胞RNA测序分析显示卵巢储备降低的卵母细胞中线粒体调控和翻译功能障碍
Xin Li,Xingwu Wu,Hui Zhang et al.
Xin Li et al.
Background: Diminished ovarian reserve (DOR) is clinically characterized by a decrease in the number of available ovarian follicles and a decline in the quality of oocytes, accompanied by hormonal changes. Low quality of ...