Application of a methodological framework for the development and multicenter validation of reliable artificial intelligence in embryo evaluation [0.03%]
胚胎评估可靠人工智能的研发及多中心验证方法学框架的应用
D Gilboa,Akhil Garg,M Shapiro et al.
D Gilboa et al.
Background: Artificial intelligence (AI) models analyzing embryo time-lapse images have been developed to predict the likelihood of pregnancy following in vitro fertilization (IVF). However, limited research exists on met...
High anti-Müllerian hormone level as a predictor of poor pregnancy outcomes in women with polycystic ovary syndrome undergoing in vitro fertilization/intracytoplasmic sperm injection: a retrospective cohort study [0.03%]
抗苗勒管激素水平作为多囊卵巢综合征患者体外受精/单精子卵胞浆内注射助孕失败的预测因素：回顾性队列研究
Fei Zhao,Duo Wen,Lin Zeng et al.
Fei Zhao et al.
Objective: To study the correlation between anti-Müllerian hormone levels and pregnancy outcomes after in vitro fertilization/intracytoplasmic sperm injection in women with polycystic ovary syndrome, which remains contro...
Sperm DNA fragmentation index: limited effectiveness on predicting embryo quality in assisted reproduction technology treatments [0.03%]
精子DNA片段指数在辅助生殖技术中的应用价值有限
Huan Jiang,Xiaolu Xia,Ying Luo et al.
Huan Jiang et al.
Purpose: Prior sperm DNA fragmentation index (DFI) thresholds for diagnosing male infertility and predicting assisted reproduction technology (ART) outcomes fluctuated between 15 and 30%, with no agreed standard. This stu...
Biochanin a modulates steroidogenesis and cellular metabolism in human granulosa cells through TAS2Rs activation: a spotlight on ovarian function [0.03%]
Biochanin A通过激活TAS2Rs调节人颗粒细胞的类固醇生成和细胞代谢：卵巢功能的一个亮点研究
Francesca Paola Luongo,Sofia Passaponti,Alesandro Haxhiu et al.
Francesca Paola Luongo et al.
Background: Endocrine-disrupting chemicals (EDCs) interfere with the endocrine system and negatively impact reproductive health. Biochanin A (BCA), an isoflavone with anti-inflammatory and estrogen-like properties, has be...
A cycle-based model to predict no usable blastocyst formation following cycles of in vitro fertilization in patients with normal ovarian reserve [0.03%]
基于周期的模型预测体外受精周期中正常卵巢储备患者的无可用囊胚形成
Xue Wang,Chen-Yue Dong,Cui-Lian Zhang et al.
Xue Wang et al.
Objective: This study aimed to develop a predictive model for the risk of no usable blastocyst formation in patients with normal ovarian reserve undergoing IVF. ...
Obesity and recurrent spontaneous abortion: the crucial role of weight management in pregnancy [0.03%]
肥胖与复发性自然流产：孕期体重管理的关键作用
Rui-Qi Wang,Zhi-Min Deng,Gan-Tao Chen et al.
Rui-Qi Wang et al.
Recurrent spontaneous abortion (RSA), characterized by the loss of two or more pregnancies, impacts approximately 1-2% of couples and poses a significant challenge for individuals of childbearing age. The precise mechanisms underlying RSA r...
Raoul Orvieto
Raoul Orvieto
As part of a conventional controlled ovarian hyperstimulation (COH) regimen, final follicular maturation is usually triggered by a single bolus dose of human chorionic gonadotropin (hCG). COH, which combines GnRH antagonist co-treatment wit...
Looking beyond the ER, PR, and HER2: what's new in the ARsenal for combating breast cancer? [0.03%]
超越ER、PR和HER2：对抗乳腺癌的新型AR靶向药物如何发力？
Tryambak Pratap Srivastava,Ruby Dhar,Subhradip Karmakar
Tryambak Pratap Srivastava
Breast cancer (BrCa) is a complex and heterogeneous disease with diverse molecular subtypes, leading to varied clinical outcomes and posing significant treatment challenges. The increasing global burden of BrCa, particularly in low- and mid...
Cell-free fat extract improves embryo development and clinical outcomes in older women with previous in-vitro fertilization failure [0.03%]
无血清脂肪酸对大龄试管婴儿失败患者的胚胎发育及临床结局的影响研究
Xiaowei Zhou,Hanfei Zhu,Jingru Duan et al.
Xiaowei Zhou et al.
Background: Preimplantation embryos in vivo are exposed to various growth factors in the female reproductive tract that are absent in in vitro embryo culture media. Cell-free fat extract exerts antioxidant, anti-ageing, a...
Who freezes her eggs and why? psychological predictors, reasons, and outcomes of social egg freezing [0.03%]
谁冻卵以及为什么？冻卵的心理预测因素、原因及结果分析
Julia Jeannine Schmid,Seraina Weber,Ulrike Ehlert
Julia Jeannine Schmid
Background: Despite the growing use of social egg freezing (SEF), research focusing on its psychological aspects is lacking. This study aimed to investigate possible psychological predictors, reasons, and outcomes of SEF ...