Proteomic investigation of protein adsorption to cerebral microdialysis membranes in surgically treated intracerebral hemorrhage patients - a pilot study [0.03%]
蛋白质组学研究蛋白质吸附至手术治疗的脑出血患者脑微透析膜上-初步研究
Lovisa Tobieson,Zita Czifra,Karin Wåhlén et al.
Lovisa Tobieson et al.
Background: Cerebral microdialysis (CMD) is a minimally invasive technique for sampling the interstitial fluid in human brain tissue. CMD allows monitoring the metabolic state of tissue, as well as sampling macromolecules...
Proteome-wide identification of arginine methylation in colorectal cancer tissues from patients [0.03%]
结肠直肠癌组织中的蛋白质组甲基化修饰筛查与验证
Yongchul Lim,Ju Yeon Lee,Su Jin Ha et al.
Yongchul Lim et al.
Background: Protein arginine methylation reaction is catalyzed by protein arginine methyltransferase (PRMT) and the modification is implicated in various diseases including cancer. Currently, thousands of arginine methyla...
Production of high-quality two-dimensional gel electrophoresis profile for marine medaka samples by using Trizol-based protein extraction approaches [0.03%]
Trizol-Based蛋白抽提方法在拟加大脂鱼样本双向凝胶电泳图谱中的应用
Celia Sze-Nga Kwok,Kaze King-Yip Lai,Sai-Wo Lam et al.
Celia Sze-Nga Kwok et al.
Background: Marine medaka is among the most popular models of fish species for ecotoxicology and environmental research and proteomic studies are useful tools for understanding the molecular responses of medaka upon expos...
Andressa Peres de Oliveira,Fernanda Luisa Basei,Priscila Ferreira Slepicka et al.
Andressa Peres de Oliveira et al.
Background: Members of the family of NEK protein kinases (NIMA-related kinases) were described to have crucial roles in regulating different aspects of the cell cycle. NEK10 was reported to take part in the maintenance of...
Protection of the transplant kidney during cold perfusion with doxycycline: proteomic analysis in a rat model [0.03%]
多西环素在冷藏灌注过程中对移植肾脏的保护作用：大鼠模型中的蛋白质组分析
Michael A J Moser,Katherine Sawicka,Jolanta Sawicka et al.
Michael A J Moser et al.
Background: It has been previously shown that doxycycline (Doxy) protects the kidney from preservation injury by inhibition of matrix metalloproteinase. However, the precise molecular mechanism involved in this protection...
Comprehensive analysis of the cardiac proteome in a rat model of myocardial ischemia-reperfusion using a TMT-based quantitative proteomic strategy [0.03%]
基于TMT的定量蛋白质组学策略分析心肌缺血再灌注大鼠模型中心脏蛋白组学的全面分析
Sun Ha Lim,Jongwon Lee,Mee-Jung Han
Sun Ha Lim
Background: Traditional studies of the cardiac proteome have mainly investigated in an animal model by two-dimensional gel electrophoresis (2-DE). However, the results have not been of satisfactory quality for an understa...
Comparative proteomic analysis of the brain and colon in three rat models of irritable bowel syndrome [0.03%]
三种肠易激综合征模型大鼠脑和结肠蛋白质组的比较分析
Beihua Zhang,Hong Xue,Wei Wang et al.
Beihua Zhang et al.
Background: Irritable bowel syndrome (IBS) has been gradually recognized as a disorder of the brain-gut interaction, but the molecular changes in the brain and colon that occur in disease development remain poorly underst...
The interactome and proteomic responses of ALKBH7 in cell lines by in-depth proteomics analysis [0.03%]
ALKBH7互作蛋白及细胞系蛋白质组响应的深度质谱分析
Shu Meng,Shaohua Zhan,Wanchen Dou et al.
Shu Meng et al.
Background: ALKBH7 is a mitochondrial protein, involved in programmed necrosis, fatty acid metabolism, cell cycle regulation, and prostate cancer disease. However, the exact roles of ALKBH7 and the underlying molecular me...
Chronic kidney disease: a review of proteomic and metabolomic approaches to membranous glomerulonephritis, focal segmental glomerulosclerosis, and IgA nephropathy biomarkers [0.03%]
慢性肾病：对膜性肾小球肾炎，局灶节段性肾小球硬化和IgA肾炎生物标志物的蛋白组学和代谢组学方法进行综述
Amir Taherkhani,Reyhaneh Farrokhi Yekta,Maede Mohseni et al.
Amir Taherkhani et al.
Chronic Kidney Disease (CKD) is a global health problem annually affecting millions of people around the world. It is a comprehensive syndrome, and various factors may contribute to its occurrence. In this study, it was attempted to provide...
Comparative iTRAQ proteomics revealed proteins associated with lobed fin regeneration in Bichirs [0.03%]
基于Bichir多鳍再生的iTRAQ蛋白组学分析
Suxiang Lu,Qian Xiong,Kang Du et al.
Suxiang Lu et al.
Background: Polypterus senegalus can fully regenerate its pectoral lobed fins, including a complex endoskeleton, with remarkable precision. However, despite the enormous potential of this species for use in medical resear...