Isolation and proteomic profiling of urinary exosomes from patients with colorectal cancer [0.03%]
结直肠癌患者尿液外泌体的分离及其蛋白质组学分析
Ling Ma,Haijiao Yu,Yubing Zhu et al.
Ling Ma et al.
Exosomes in the body fluid are effective cell-derived membranous structures transferring various molecules to mediate intercellular communication. The expression of protein in the urinary exosomes from the colorectal cancer (CRC) patients c...
Quantitative proteomics analysis revealed the potential role of lncRNA Ftx in cardiomyocytes [0.03%]
定量蛋白质组学分析揭示了长链非编码RNA Ftx在心肌细胞中的潜在作用
Xiangfei Sun,Ying Jiang,Qingbao Li et al.
Xiangfei Sun et al.
Objective: This study aims to decode the proteomic signature of cardiomyocytes in response to lncRNA Ftx knockdown and overexpression via proteomic analysis, and to study the biological role of lncRNA Ftx in cardiomyocyte...
Proteomic Analysis of Protective Effects of Dl-3-n-Butylphthalide against mpp + -Induced Toxicity via downregulating P53 pathway in N2A Cells [0.03%]
基于P53通路下调分析DL-3-n-丁基磷花酯对MPP+诱导N2A细胞毒性防护作用的蛋白质谱研究
Yuan Zhao,Jian Zhang,Yidan Zhang et al.
Yuan Zhao et al.
Background: Dl-3-n-butylphthalide (NBP) is an important medial therapy for acute ischemic stroke in China. Recent studied have revealed that NBP not only rescued the loss of dopaminergic neurons in cellular and animal mod...
Responses of the tree peony (Paeonia suffruticosa, Paeoniaceae) cultivar 'Yu Hong' to heat stress revealed by iTRAQ-based quantitative proteomics [0.03%]
基于iTRAQ的定量蛋白质组学揭示了热应力对树牡丹(Paeonia suffruticosa, Paeoniaceae)品种'Yu Hong'的影响
Jin Ma,Qun Wang,Ling-Ling Wei et al.
Jin Ma et al.
Horticulture productivity has been increasingly restricted by heat stress from growing global warming, making it far below the optimum production capacity. As a popular ornamental cultivar of tree peony, Paeonia suffruticosa 'Yu Hong' has a...
TMT-based quantitative proteomics analysis of the effects of Jiawei Danshen decoction myocardial ischemia-reperfusion injury [0.03%]
定量蛋白质组学分析加味丹参饮对心肌缺血再灌注损伤的影响
Xiang-Mei Zhu,Yang Tan,Yu-He Shi et al.
Xiang-Mei Zhu et al.
Background: Every year, approximately 17 million people worldwide die due to coronary heart disease, with China ranking second in terms of the death toll. Myocardial ischemia-reperfusion injury (MIRI) significantly influe...
Profiles of transcriptome and metabolic pathways after hypobaric hypoxia exposure [0.03%]
低气压缺氧暴露后的转录组和代谢通路特征分析
Jin Xu,Wen-Jie Chen,Zhan Wang et al.
Jin Xu et al.
Background: Hypoxia is a risk factor for non-alcoholic fatty liver diseases, leading to permanent imbalance of liver lipid homeostasis and steatohepatitis. However, a detailed understanding of the metabolic genes and path...
A combined protein toxin screening based on the transcriptome and proteome of Solenopsis invicta [0.03%]
基于入侵火蚁转录组和蛋白质组的联合蛋白毒素筛选技术
Liuyang Cai,Fengling Yang,Yongfang Wang et al.
Liuyang Cai et al.
Background: Multi-omics technology provides a good tool to analyze the protein toxin composition and search for the potential pathogenic factors of Solenopsis invicta, under the great harm of the accelerated invasion in s...
Effect of downregulated citrate synthase on oxidative phosphorylation signaling pathway in HEI-OC1 cells [0.03%]
丙酮酸脱氢酶下调对HEI-OC1细胞氧化磷酸化信号通路的影响
Xiaowen Xu,Yue Liu,Jun Luan et al.
Xiaowen Xu et al.
Background: Citrate Synthase (Cs) gene mutation (locus ahL4) has been found to play an important role in progressive hearing loss of A/J mice. HEI-OC1 cells have been widely used as an in vitro system to study cellular an...
Tear proteomics analysis of patient suffered from delayed mustard gas keratopathy [0.03%]
迟发性芥子气角膜病患者泪液蛋白质组学分析
Shahram Parvin,Alireza Shahriary,Hossein Aghamollaei et al.
Shahram Parvin et al.
Understanding the molecular and cellular mechanisms involved in the pathogenesis of ocular injured induced by mustard gas can help better identify complications and discover appropriate therapies. This study aimed to analyze the proteomics ...
Jiang-Feng Liu,Yue Wu,Ye-Hong Yang et al.
Jiang-Feng Liu et al.
Background: Aging is a complex biological process accompanied by a time-dependent functional decline that affects most living organisms. Omics studies help to comprehensively understand the mechanism of aging and discover...