Genome-wide computational analysis of the dirigent gene family in Solanum lycopersicum [0.03%]
番茄果实发育期DIRIGENT基因家族的全基因组鉴定及表达分析
Muhammad Abu Bakar Saddique,Ge Guan,Beibei Hu et al.
Muhammad Abu Bakar Saddique et al.
Background: Dirigent (DIR) genes play a key role in the development of organic products in plants. They confer conformational influence on processes that lack stereoselectivity and regioselectivity through processes that ...
Mechanism of the cardioprotective effect of empagliflozin on diabetic nephropathy mice based on the basis of proteomics [0.03%]
基于蛋白质组学的恩格列净对糖尿病肾病小鼠心脏保护作用机制研究
Zongchao Yu,Yongping Lu,Mengxian Zhang et al.
Zongchao Yu et al.
Diabetic nephropathy affects a significant proportion of individuals with diabetes, and its progression often leads to cardiovascular disease and infections before the need for renal replacement therapy arises. Empagliflozin has been shown ...
NEK10 kinase ablation affects mitochondrial morphology, function and protein phosphorylation status [0.03%]
NEK10激酶缺失影响线粒体形态、功能及蛋白磷酸化状态
Andressa Peres de Oliveira,Claudia D C Navarro,Pedro Rafael F Dias et al.
Andressa Peres de Oliveira et al.
Background: NEK10, a serine/threonine/tyrosine kinase belonging to the NEK (NIMA-related kinases) family, has been associated with diverse cellular processes. However, no specific target pathways have been identified. Our...
Spatial proteomics: unveiling the multidimensional landscape of protein localization in human diseases [0.03%]
空间蛋白质组学：揭示人类疾病中蛋白质定位的多维景观
Mengyao Wu,Huihui Tao,Tiantian Xu et al.
Mengyao Wu et al.
Spatial proteomics is a multidimensional technique that studies the spatial distribution and function of proteins within cells or tissues across both spatial and temporal dimensions. This field multidimensionally reveals the complex structu...
iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency [0.03%]
基于iTRAQ的蛋白质组学研究发现LAMP2下调与HIV-1潜伏相关
Lin Yin,Qimin Wang,Siyuan Liu et al.
Lin Yin et al.
Background: Patients with immunodeficiency virus-1 (HIV-1) infection are challenging to be cured completely due to the existence of HIV-1 latency reservoirs. However, the knowledge of the mechanisms and biomarkers associa...
A methodological exploration of distinguishing hair quality based on hair proteomics [0.03%]
基于毛发蛋白质组学区分毛发质量的方法学探索研究
Xiaolin Wu,Tao Zhang,Mingsong Mao et al.
Xiaolin Wu et al.
Hair is an advantageous biological sample due to its recordable, collectable, and storable nature. Hair's primary components are keratin and keratin-associated proteins. Owing to its abundance of cystine, keratin possesses impressive mechan...
Exosome proteomes reveal glycolysis-related enzyme enrichment in primary canine mammary gland tumor compared to metastases [0.03%]
exo体蛋白表明与转移相比原发犬类乳腺肿瘤中富含糖酵解相关酶
Hui-Su Kim,Je-Yoel Cho
Hui-Su Kim
Objective: Numerous evidence has highlighted the differences between primary tumors and metastases. Nonetheless, the differences in exosomal proteins derived from primary tumor and metastases remain elusive. Here, we aime...
Comparative proteomics reveals different protein expression in platelets in patients with alcoholic liver cirrhosis [0.03%]
比较蛋白质组学显示酒精性肝硬化的病人血小板中不同的蛋白质表达
Nima Haji Begli,Cora Freund,Karl-Heinz Weiss et al.
Nima Haji Begli et al.
Background: The role of platelets in disease progression as well as the function of platelets as part of the haemostatic and immunological system in patients with liver cirrhosis is only incompletely understood. This is p...
Methionine enkephalin (MENK) protected macrophages from ferroptosis by downregulating HMOX1 and ferritin [0.03%]
甲硫氨酸脑啡肽(MENK)通过降低HMOX1和铁蛋白的表达保护巨噬细胞免受铁死亡
Jing Tian,Wenrui Fu,Zifeng Xie et al.
Jing Tian et al.
Objective: The aim of this work was to investigate the immunological effect of MENK by analyzing the protein spectrum and bioinformatics of macrophage RAW264.7, and to explore the relationship between macrophage and ferro...
Proteomic profile of tepary bean seed storage proteins in germination with low water potential [0.03%]
低水分势萌发对菜豆种子贮藏蛋白的影响
Daniel Padilla-Chacón,Laura Campos-Patiño,Cecilia B Peña-Valdivia et al.
Daniel Padilla-Chacón et al.
Background: Tepary bean (Phaseolus acutifolius A. Gray) is one of the five species domesticated from the genus Phaseolus with genetic resistance to biotic and abiotic stress. To understand the mechanisms underlying drough...