Biomimetic gold nano-modulator for deep-tumor NIR-II photothermal immunotherapy via gaseous microenvironment remodeling strategy [0.03%]
通过气体微环境重塑策略实现深部肿瘤近红外二区光热免疫治疗的仿生金纳米调制器
Honglin Huang,Zhengxin Xie,Ningxi Li et al.
Honglin Huang et al.
Introduction: Effective immunotherapeutic treatment of solid tumors has been greatly challenged by the complex hostile tumor immunosuppressive microenvironment (TIME), which typically involves hypoxia and immunosuppressio...
Blocking copper transporter protein-dependent drug efflux with albumin-encapsulated Pt(IV) for synergistically enhanced chemo-immunotherapy [0.03%]
利用白蛋白包裹的Pt(IV)阻断铜转运蛋白依赖的药物外排以协同增强化学免疫治疗
Man Fang,Lei Cao,Zhao Zhang et al.
Man Fang et al.
Non-small cell lung cancer (NSCLC) represents the most prevalent form of lung cancer, exerting a substantial impact on global health. Cisplatin-based chemotherapy is the standard treatment for NSCLC, but resistance and severe side effects p...
Protective effects of bone marrow mesenchymal stem cell-derived exosomes loaded cerium dioxide nanoparticle against deoxynivalenol-induced liver damage [0.03%]
骨髓间充质干细胞来源的富铈纳米粒子外泌体对脱氧雪腐镰刀菌烯醇致肝损伤的保护作用
Zitong Meng,Mingmeng Tang,Shiyin Xu et al.
Zitong Meng et al.
Background: Deoxynivalenol (DON), a mycotoxin produced by Fusarium species, posed significant threats to food safety and human health due to its widespread prevalence and detrimental effects. Upon exposure, the liver, whi...
Functions and application of circRNAs in vascular aging and aging-related vascular diseases [0.03%]
circRNA在血管衰老和衰老相关血管疾病中的功能及应用
Sha-Qi He,Bei Huang,Feng Xu et al.
Sha-Qi He et al.
Circular RNAs (circRNAs), constituting a novel class of endogenous non-coding RNAs generated through the reverse splicing of mRNA precursors, possess the capacity to regulate gene transcription and translation. Recently, the pivotal role of...
Stem cells derived exosome laden oxygen generating hydrogel composites with good electrical conductivity for the tissue-repairing process of post-myocardial infarction [0.03%]
用于心肌梗死后组织修复过程的具有良好导电性的干细胞衍生的外体负载型氧气生成水凝胶复合材料
Zhaoyan Xu,Wanzi Hong,Yuanxi Mo et al.
Zhaoyan Xu et al.
Acute myocardial infarction (AMI) destroys heart cells by disrupting the oxygen supply. Improving oxygen delivery to the injured area may avoid cell death and regenerate the heart. We present the creation of oxygen-producing injectable bio-...
Correction: An antioxidant nanozyme for targeted cardiac fbrosis therapy post myocardial infarction [0.03%]
纠正：用于心肌梗死后靶向心脏纤维化治疗的抗氧化纳米酶
Ziyi Gu,Xueliang Liu,Zhen Qi et al.
Ziyi Gu et al.
Published Erratum
Journal of nanobiotechnology. 2025 Mar 17;23(1):214. DOI:10.1186/s12951-025-03299-w 2025
Functional nanozyme system for synergistic tumor immunotherapy via cuproptosis and ferroptosis activation [0.03%]
通过激活铜死亡和铁死亡实现协同肿瘤免疫治疗的功能性纳米酶系统
Lina Gu,Ying Sun,Tingjie Bai et al.
Lina Gu et al.
Elevated copper levels induce tumor cuproptosis and ferroptosis, leading to immunogenic cell death and subsequent antitumor immune responses. However, dysregulated copper metabolism in tumor cells maintains homeostatic copper balance, while...
Retraction Note: Eobania vermiculata whole-body muscle extract-loaded chitosan nanoparticles enhanced skin regeneration and decreased pro-inflammatory cytokines in vivo [0.03%]
撤稿说明：Eobania vermiculata全身肌肉提取物负载的壳聚糖纳米粒促进皮肤再生和降低体内促炎细胞因子含量
Alyaa Farid,Adham Ooda,Ahmed Nabil et al.
Alyaa Farid et al.
Harnessing the power of traceable system C-GAP: homologous-targeting to fire up T-cell immune responses with low-dose irradiation [0.03%]
可追溯系统C-GAP的力量：利用低剂量照射的同源靶向增强T细胞免疫反应
Weijie Zhuang,Kuangwu Pan,Jie Wu et al.
Weijie Zhuang et al.
While radiotherapy-induced immunogenic cell death (ICD) holds potential for enhancing cancer immunotherapy, the conventional high-dose irradiation often leads to an immunosuppressive microenvironment and systemic toxicity. Therefore, a biom...
Injectable hydrogels with ROS-triggered drug release enable the co-delivery of antibacterial agent and anti-inflammatory nanoparticle for periodontitis treatment [0.03%]
ROS触发药物释放的可注射水凝胶能够协同运输抗生素和抗炎纳米粒子用于牙周病治疗
Yujing Zhu,Ziliang Xiu,Xiaoxi Jiang et al.
Yujing Zhu et al.
Periodontitis, a chronic inflammatory disease caused by bacteria, is characterized by localized reactive oxygen species (ROS) accumulation, leading to an inflammatory response, which in turn leads to the destruction of periodontal supportin...