Dual-loaded nano pesticide system based on industrial grade scaleable carrier materials with combinatory efficacy and improved safety [0.03%]
一种基于工业级可扩展载体材料的双载纳米农药体系，具有协同增效和改善安全性的特点
Ningjun Li,Jianxia Cui,Jianjiang Zhao et al.
Ningjun Li et al.
Repeated and widespread use of single chemical pesticides raises concerns about efficiency and safety, developing multi-component synergistic pesticides provides a new route for efficient control of diseases. Most commercial compound formul...
Injectable hybrid hydrogels enable enhanced combination chemotherapy and roused anti-tumor immunity in the synergistic treatment of pancreatic ductal adenocarcinoma [0.03%]
注射型杂化水凝胶在胰腺导管腺癌协同治疗中增强联合化疗和激发抗肿瘤免疫反应
Hao Zhou,Wei Wang,Zedong Cai et al.
Hao Zhou et al.
Chemotherapy and immunotherapy have shown no significant outcome for unresectable pancreatic ductal adenocarcinoma (PDAC). Multi-drug combination therapy has become a consensus in clinical trials to explore how to arouse anti-tumor immunity...
Proangiogenic effect and underlying mechanism of holmium oxide nanoparticles: a new biomaterial for tissue engineering [0.03%]
纳米Holmium氧化物的促血管生成效应及其作用机制：组织工程新材料
Yuxiao Luo,Yifan Zheng,Ziwei Chen et al.
Yuxiao Luo et al.
Background: Early angiogenesis provides nutrient supply for bone tissue repair, and insufficient angiogenesis will lead tissue engineering failure. Lanthanide metal nanoparticles (LM NPs) are the preferred materials for t...
Combined SERS-Raman screening of HER2-overexpressing or silenced breast cancer cell lines [0.03%]
HER2高表达或沉默的乳腺癌细胞系的组合SERS-Raman筛选检测法
Sara Spaziani,Alessandro Esposito,Giovannina Barisciano et al.
Sara Spaziani et al.
Background: Breast cancer (BC) is a heterogeneous neoplasm characterized by several subtypes. One of the most aggressive with high metastasis rates presents overexpression of the human epidermal growth factor receptor 2 (...
Electroactive Brevundimonas diminuta consortium mediated selenite bioreduction, biogenesis of selenium nanoparticles and bio-electricity generation [0.03%]
电解活化的Brevundimonas diminuta菌群介导的亚硒酸盐生物还原、硒纳米颗粒的生物合成及生物发电性能研究
Ebtehag A E Sakr,Dena Z Khater,Kamel M El-Khatib
Ebtehag A E Sakr
In this study, highly selenite-resistant strains belonging to Brevundimonas diminuta (OK287021, OK287022) genus were isolated from previously operated single chamber microbial fuel cell (SCMFC). The central composite design showed that the ...
NIR-responsive CN-Pt-GEM hydrogel induces necroptosis and immunotherapeutic responses prevent postoperative recurrence and wound infection in lung carcinoma [0.03%]
近红外响应性CN-Pt-GEM水凝胶诱导坏死性凋亡和免疫治疗反应预防肺癌术后复发及伤口感染
Meng Wang,Rui Cai,Zhiwu Zhang et al.
Meng Wang et al.
Background: Cancer recurrence following surgical resection is a major cause of treatment failure. Finding effective methods to prevent postoperative recurrence and wound infection is an important component of successful s...
Advancing fluorescence imaging: enhanced control of cyanine dye-doped silica nanoparticles [0.03%]
推进荧光成像研究：增强型氰基染料掺杂二氧化硅纳米颗粒的控制能力
Taewoong Son,Minseo Kim,Minsuk Choi et al.
Taewoong Son et al.
Background: Silica nanoparticles (SNPs) have immense potential in biomedical research, particularly in drug delivery and imaging applications, owing to their stability and minimal interactions with biological entities suc...
Tumor microenvironment responsive nano-herb and CRISPR delivery system for synergistic chemotherapy and immunotherapy [0.03%]
肿瘤微环境响应的纳米中药和CRISPR递送系统协同化疗和免疫治疗
Yuanyuan Jia,Yuhui Yao,Lingyao Fan et al.
Yuanyuan Jia et al.
Chemoresistance remains a significant challenge for effective breast cancer treatment which leads to cancer recurrence. CRISPR-directed gene editing becomes a powerful tool to reduce chemoresistance by reprogramming the tumor microenvironme...
Photosensitive and dual-targeted chromium nanoparticle delivering small interfering RNA YTHDF1 for molecular-targeted immunotherapy in liver cancer [0.03%]
用于肝癌分子靶向免疫治疗的光敏和双重靶向递送小干扰RNA沉默YTHDF1的纳米药物疗法
Shang Chen,Yan He,Xin Huang et al.
Shang Chen et al.
Tumor-associated macrophages (TAMs) are a promising target for cancer immunotherapy, but delivering therapeutic agents to TAMs within the tumor microenvironment (TME) is challenging. In this study, a photosensitive, dual-targeting nanoparti...
Nanomaterials-assisted gene editing and synthetic biology for optimizing the treatment of pulmonary diseases [0.03%]
纳米材料辅助的基因编辑和合成生物学在优化肺部疾病治疗中的应用
Lanjie Lei,Wenjie Pan,Xin Shou et al.
Lanjie Lei et al.
The use of nanomaterials in gene editing and synthetic biology has emerged as a pivotal strategy in the pursuit of refined treatment methodologies for pulmonary disorders. This review discusses the utilization of nanomaterial-assisted gene ...