Liver-specific delivery of spherical DNA frameworks for alleviation of hepatic ischemic reperfusion injury [0.03%]
肝特异性输送球形DNA框架用于减轻肝脏缺血再灌注损伤
Hao Wang,Li Wen,Hao Wei et al.
Hao Wang et al.
DNA nanostructures have long been developed for biomedical purposes, but their controlled delivery in vivo proposes a major challenge for disease theranostics. We previously reported that DNA nanostructures on the scales of tens and hundred...
Zoya Iqbal,Khurrum Rehman,Ayesha Mahmood et al.
Zoya Iqbal et al.
Messenger RNA (mRNA) has emerged as a promising therapeutic molecule with numerous clinical applications in treating central nervous system disorders, tumors, COVID-19, and other diseases. mRNA therapies must be encapsulated into safe, stab...
Injective hydrogel loaded with liposomes-encapsulated MY-1 promotes wound healing and increases tensile strength by accelerating fibroblast migration via the PI3K/AKT-Rac1 signaling pathway [0.03%]
负载包封MY-1的脂质体的注射型水凝胶通过PI3K/AKT-Rac1信号通路促进伤口愈合和增加拉伸强度（英文）
Chunhao Zhou,Zhihai Cai,Jialiang Guo et al.
Chunhao Zhou et al.
Failed skin wound healing, through delayed wound healing or wound dehiscence, is a global public health issue that imposes significant burdens on individuals and society. Although the application of growth factor is an effective method to i...
A black phosphorus nanosheet-based RNA delivery system for prostate cancer therapy by increasing the expression level of tumor suppressor gene PTEN via CeRNA mechanism [0.03%]
一种基于黑磷纳米片的用于前列腺癌治疗的RNA传递系统通过竞争性内源RNA机制增加抑癌基因PTEN表达水平
Shunye Su,Leyi Liu,Qingfeng Fu et al.
Shunye Su et al.
Background: Prostate cancer (PCa) has a high incidence in men worldwide, and almost all PCa patients progress to the androgen-independent stage which lacks effective treatment measures. PTENP1, a long non-coding RNA, has ...
ZnO NPs induce miR-342-5p mediated ferroptosis of spermatocytes through the NF-κB pathway in mice [0.03%]
ZnO NPs通过NF-κB信号诱导小鼠精原细胞miR-342-5p介导的铁死亡机制研究
Guangyu Liu,Jing Lv,Yifan Wang et al.
Guangyu Liu et al.
Background: Zinc oxide nanoparticle (ZnO NP) is one of the metal nanomaterials with extensive use in many fields such as feed additive and textile, which is an emerging threat to human health due to widely distributed in ...
Zno nanoparticles: improving photosynthesis, shoot development, and phyllosphere microbiome composition in tea plants [0.03%]
锌纳米颗粒改善茶树光合作用、茎叶生长和叶片微生物组组成
Hao Chen,Yujie Song,Yu Wang et al.
Hao Chen et al.
Background: Nanotechnology holds revolutionary potential in the field of agriculture, with zinc oxide nanoparticles (ZnO NPs) demonstrating advantages in promoting crop growth. Enhanced photosynthetic efficiency is closel...
Nanobody peptide conjugate: a novel CD163 based broad neutralizing strategy against porcine reproductive and respiratory syndrome virus [0.03%]
纳米抗体肽缀合物：一种基于CD163的抗猪繁殖与呼吸综合征病毒广谱中和新策略
Haotian Yang,Meiqi Sun,He Qiu et al.
Haotian Yang et al.
Background: Porcine reproductive and respiratory syndrome virus (PRRSV) is a prevalent swine pathogen, which has caused adverse impact on the global swine industry for almost 30 years. However, due to the immune suppressi...
Functional hydrogels for hepatocellular carcinoma: therapy, imaging, and in vitro model [0.03%]
用于肝细胞癌的水凝胶：治疗，影像和体外模型
Xiaoying Xu,Yu Liu,Yanyan Liu et al.
Xiaoying Xu et al.
Hepatocellular carcinoma (HCC) is among the most common malignancies worldwide and is characterized by high rates of morbidity and mortality, posing a serious threat to human health. Interventional embolization therapy is the main treatment...
NIR-responsive electrospun nanofiber dressing promotes diabetic-infected wound healing with programmed combined temperature-coordinated photothermal therapy [0.03%]
近红外响应的静电纺纳米纤维敷料可促进糖尿病感染性伤口愈合并实现程序化温控光热治疗
Jinlang Fu,Ding Wang,Zinan Tang et al.
Jinlang Fu et al.
Background: Diabetic wounds present significant challenges, specifically in terms of bacterial infection and delayed healing. Therefore, it is crucial to address local bacterial issues and promote accelerated wound healin...
Graphene oxide quantum dots-loaded sinomenine hydrochloride nanocomplexes for effective treatment of rheumatoid arthritis via inducing macrophage repolarization and arresting abnormal proliferation of fibroblast-like synoviocytes [0.03%]
用于有效治疗类风湿性关节炎的氧化石墨烯量子点-氯化蛇毒碱纳米复合材料通过诱导巨噬细胞重编程和阻止滑膜纤维母细胞样增殖异常作用
Ye Lin,Yuanyuan Tang,Ouyang Yi et al.
Ye Lin et al.
The characteristic features of the rheumatoid arthritis (RA) microenvironment are synovial inflammation and hyperplasia. Therefore, there is a growing interest in developing a suitable therapeutic strategy for RA that targets the synovial m...