Nanoparticle and microparticle-based systems for enhanced oral insulin delivery: A systematic review and meta-analysis [0.03%]
基于纳米颗粒和微粒的口服胰岛素递送增强系统：系统性评审与元分析
Carlos E Romero-Carmona,Juan I Chávez-Corona,Enrique Lima et al.
Carlos E Romero-Carmona et al.
Diabetes mellitus (DM) prevalence is rising worldwide. Current therapies comprising subcutaneous insulin injections can cause adverse effects such as lipodystrophy, local reactions like redness and swelling, fluid retention, and allergic re...
Role of PCBP2 in regulating nanovesicles loaded with curcumin to mitigate neuroferroptosis in neural damage caused by heat stroke [0.03%]
PCBP2调节载姜黄素纳米囊泡作用于中暑所致神经损伤的抑铁抗 ferrtroptosis 机制研究
Fei Guo,Yizhan Wu,Guangjun Wang et al.
Fei Guo et al.
Objective: This study aims to elucidate the mechanisms by which nanovesicles (NVs) transport curcumin(CUR) across the blood-brain barrier to treat hypothalamic neural damage induced by heat stroke by regulating the expres...
Copper-coordination driven brain-targeting nanoassembly for efficient glioblastoma multiforme immunotherapy by cuproptosis-mediated tumor immune microenvironment reprogramming [0.03%]
铜配位驱动的脑靶向纳米组装体通过铜死亡介导的肿瘤免疫微环境重编程有效治疗多形性胶质母细胞瘤
Yang Chen,Hailong Tian,Xiaodian Zhang et al.
Yang Chen et al.
Limited drug accumulation and an immunosuppressive microenvironment are the major bottlenecks in the treatment of glioblastoma multiforme (GBM). Herein, we report a copper-coordination driven brain-targeting nanoassembly (TCe6@Cu/TP5 NPs) f...
Integrating electrospun aligned fiber scaffolds with bovine serum albumin-basic fibroblast growth factor nanoparticles to promote tendon regeneration [0.03%]
融合型静电纺丝齐轴纤维支架及牛血清白蛋白-碱性成纤维细胞生长因子纳米颗粒促进肌腱再生的研究
Yuwan Li,Zhen Ge,Ziming Liu et al.
Yuwan Li et al.
Background: Electrospun nanofiber scaffolds have been widely used in tissue engineering because they can mimic extracellular matrix-like structures and offer advantages including high porosity, large specific surface area...
PDGFR-α shRNA-polyplex for uveal melanoma treatment via EMT mediated vasculogenic mimicry interfering [0.03%]
通过EMT介导的血管生成模拟干扰进行脉络膜黑色素瘤治疗的PDGFR-α shRNA-聚复合物
Jiahao Wang,Zhirong Chen,Peiyi Zhao et al.
Jiahao Wang et al.
Up to 50% of individuals with uveal melanoma (UM), a frequent cancer of the eye, pass away from metastases. One of the major challenges in treating UM is the role of receptor tyrosine kinases (RTKs), which mediate the epithelial-mesenchymal...
Spatiotemporal-controllable ROS-responsive camptothecin nano-bomb for chemo/photo/immunotherapy in triple-negative breast cancer [0.03%]
可控型ROS响应性喜树碱纳米炸弹用于三阴乳腺癌的化疗/光动力免疫联合治疗研究
Wenjie Xu,Zhaokui Zeng,Yucheng Tang et al.
Wenjie Xu et al.
Chemotherapy is still one of the major approaches in triple-negative breast cancer (TNBC) treatment. The development of new formulations for classic chemotherapeutic drugs remains interests in studies. Camptothecin (CPT) is powerful antitum...
Unveiling the molecular blueprint of SKP-SCs-mediated tissue engineering-enhanced neuroregeneration [0.03%]
揭示SKP-SCs介导的组织工程增强神经再生的分子蓝图
Hui Zhu,Ying Wang,Siyuan Xu et al.
Hui Zhu et al.
Peripheral nerve injury poses a significant challenge to the nervous system's regenerative capacity. We previously described a novel approach to construct a chitosan/silk fibroin nerve graft with skin-derived precursor-induced Schwann cells...
Natural epigallocatechin-3-gallocarboxylate nanoformulation loaded doxorubicin to construct a novel and low cardiotoxicity chemotherapeutic drug for high-efficiency breast cancer therapy [0.03%]
一种新型低心脏毒性的高效治疗乳腺癌的化疗药物——用天然儿茶素纳米载体负载阿霉素制备多功能抗癌药研究
Ke Wang,Siqi Geng,Fang Wang et al.
Ke Wang et al.
Anthracycline doxorubicin (DOX) remains the first-line chemotherapeutic drug for the efficient treatment of breast cancer, but its severe cardiotoxicity limits its long-term application in clinical tumor chemotherapy. Until now, the pathoge...
Reprogramming tumor-associated macrophages with lipid nanosystems reduces PDAC tumor burden and liver metastasis [0.03%]
使用脂质纳米系统重新编程肿瘤相关巨噬细胞可减少胰腺癌的肿瘤负荷和肝转移
Adrián Palencia-Campos,Laura Ruiz-Cañas,Marcelina Abal-Sanisidro et al.
Adrián Palencia-Campos et al.
Background: Pancreatic ductal adenocarcinoma (PDAC) requires innovative therapeutic strategies to counteract its progression and metastatic potential. Since the majority of patients are diagnosed with advanced metastatic ...
Correction: Immunotoxicity assessment of CdSe/ZnS quantum dots in macrophages, lymphocytes and BALB/c mice [0.03%]
关于CdSe/ZnS量子点的免疫毒理学评价的研究勘误：对巨噬细胞、淋巴细胞和BALB/c小鼠的影响
Xiaomei Wang,Jinglin Tian,Ken-Tye Yong et al.
Xiaomei Wang et al.
Published Erratum
Journal of nanobiotechnology. 2024 Dec 24;22(1):794. DOI:10.1186/s12951-024-02991-7 2024