A bioinspired supramolecular nanoprodrug for precision therapy of B-cell non-Hodgkin's lymphoma [0.03%]
一种生物启发的超分子纳米前药精准治疗B细胞非霍奇金淋巴瘤
Qixiong Zhang,Yuhan Tian,Yanrui Yang et al.
Qixiong Zhang et al.
Fludarabine (FA) is still considered as a first-line chemotherapy drug for hematological tumors related to B lymphocytes. However, it is worth noting that the non-specific distribution and non-different cytotoxicity of FA may lead to irreve...
Metal ions-anchored bacterial outer membrane vesicles for enhanced ferroptosis induction and immune stimulation in targeted antitumor therapy [0.03%]
金属离子锚定细菌外膜囊泡用于增强铁死亡诱导和免疫刺激的靶向抗肿瘤治疗
Ying Sun,Yan-Yan Ma,Shijie Shangguan et al.
Ying Sun et al.
The activation of ferroptosis presents a versatile strategy for enhancing the antitumor immune responses in cancer therapy. However, developing ferroptosis inducers that combine high biocompatibility and therapeutic efficiency remains chall...
Future embracing: exosomes driving a revolutionary approach to the diagnosis and treatment of idiopathic membranous nephropathy [0.03%]
拥抱未来：外泌体驱动特发性膜性肾病的诊断和治疗革命
Lin Wang,Jinxiang Wang,Ao Xu et al.
Lin Wang et al.
Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults and is associated with high rates of end-stage renal disease. Early detection and precise interventions are crucial for improving patient prognosis and quality o...
Tea polyphenol nanoparticles enable targeted siRNA delivery and multi-bioactive therapy for abdominal aortic aneurysms [0.03%]
茶多酚纳米颗粒能够针对腹主动脉瘤实现siRNA递送及多重生物活性治疗
Zhen Wu,Peng Zhang,Jie Yue et al.
Zhen Wu et al.
Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease, while there is a lack of pharmaceutical interventions to halt AAA progression presently. To address the multifaceted pathology of AAA, this work develops a novel multif...
Spermatozoon-propelled microcellular submarines combining innate magnetic hyperthermia with derived nanotherapies for thrombolysis and ischemia mitigation [0.03%]
结合固有磁超热和衍生纳米疗法的精子驱动微细胞潜艇用于溶栓和缺血减缓
Pei-Wei Weng,Chia-Hung Liu,Pei-Ru Jheng et al.
Pei-Wei Weng et al.
Thrombotic cardiovascular diseases are a prevalent factor contributing to both physical impairment and mortality. Thrombolysis and ischemic mitigation have emerged as leading contemporary therapeutic approaches for addressing the consequenc...
Advances in hybridized nanoarchitectures for improved oro-dental health [0.03%]
用于改善口腔牙齿健康的杂化纳米结构的新进展
Jun Guo,Pei Wang,Yuyao Li et al.
Jun Guo et al.
On a global note, oral health plays a critical role in improving the overall human health. In this vein, dental-related issues with dentin exposure often facilitate the risk of developing various oral-related diseases in gums and teeth. Sev...
The elasticity of silicone-stabilized liposomes has no impact on their in vivo behavior [0.03%]
硅胶稳定脂质体的弹性对体内行为没有影响
Alicja Hinz,Joanna Lewandowska-Łańcucka,Ewa Werner et al.
Alicja Hinz et al.
Background: The elastomechanical properties of nanocarriers have recently been discussed as important for the efficient delivery of various therapeutics. Some data indicate that optimal nanocarriers' elasticity can modula...
Sustained release of 5-aminosalicylic acid from azoreductase-responsive polymeric prodrugs for prolonged colon-targeted colitis therapy [0.03%]
一种偶氮酶响应型聚丙烯前药载体系统用于制备肠溶5氨基水杨酸制剂及延长给药时间治疗结肠炎
Sicheng Tang,Wenchao Wang,Yijian Wang et al.
Sicheng Tang et al.
Ulcerative colitis (UC) is a challenging inflammatory gastrointestinal disorder, whose therapies encounter limitations in overcoming insufficient colonic retention and rapid systemic clearance. In this study, we report an innovative polymer...
Correction:Targeting SUMOylation with an injectable nanocomposite hydrogel to optimize radiofrequency ablation therapy for hepatocellular carcinoma [0.03%]
纠正：使用可注射纳米复合水凝胶靶向SUMO化以优化射频消融治疗肝细胞癌的方法
Junfeng Liu,Xi Li,Jiawen Chen et al.
Junfeng Liu et al.
Published Erratum
Journal of nanobiotechnology. 2024 Aug 2;22(1):462. DOI:10.1186/s12951-024-02690-3 2024
Exosomes as therapeutic and drug delivery vehicle for neurodegenerative diseases [0.03%]
外泌体在神经退行性疾病治疗和药物递送中的作用
Zeinab Nouri,Ashkan Barfar,Sahra Perseh et al.
Zeinab Nouri et al.
Neurodegenerative disorders are complex, progressive, and life-threatening. They cause mortality and disability for millions of people worldwide. Appropriate treatment for neurodegenerative diseases (NDs) is still clinically lacking due to ...