Correction: A nanozyme-functionalized bilayer hydrogel scaffold for modulating the inflammatory microenvironment to promote osteochondral regeneration [0.03%]
题图:负载纳米酶的双层水凝胶支架调节炎性微环境促进软骨-骨再生研究进展
Chuan Hu,Ruipeng Huang,Jiechao Xia et al.
Chuan Hu et al.
Published Erratum
Journal of nanobiotechnology. 2024 Aug 23;22(1):505. DOI:10.1186/s12951-024-02768-y 2024
Intranasal delivery of small extracellular vesicles reduces the progress of amyotrophic lateral sclerosis and the overactivation of complement-coagulation cascade and NF-ĸB signaling in SOD1G93A mice [0.03%]
经鼻递送小细胞外囊泡可减缓SOD1G93A小鼠渐冻症的进程并抑制补体凝血级联反应和NF-κB信号通路的过度激活
Jinrui Zhou,Fuxiang Li,Bin Jia et al.
Jinrui Zhou et al.
Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by progressive motoneuron degeneration, and effective clinical treatments are lacking. In this study, we evaluated whether intranasal delivery of mesenchymal stem cell-der...
Beyond hype: unveiling the Real challenges in clinical translation of 3D printed bone scaffolds and the fresh prospects of bioprinted organoids [0.03%]
超越炒作:揭开3D打印骨支架临床转化的真实挑战及生物打印类器官的新兴前景
Xiangyu Zhao,Na Li,Ziqi Zhang et al.
Xiangyu Zhao et al.
Bone defects pose significant challenges in healthcare, with over 2 million bone repair surgeries performed globally each year. As a burgeoning force in the field of bone tissue engineering, 3D printing offers novel solutions to traditional...
A novel HER2 targeting nanoagent self-assembled from affibody-epothilone B conjugate for cancer therapy [0.03%]
一种用于癌症治疗的新型HER2靶向纳药:Affibody-埃坡霉素B缀合物自组装纳米药物
Xuelin Xia,Xiaoyuan Yang,Wenhui Gao et al.
Xuelin Xia et al.
Epothilone B (Epo B), a promising antitumor compound effective against various types of cancer cells in vitro. However, its poor selectivity for tumor cells and inadequate therapeutic windows significantly limit its potential clinical appli...
Optimal development of apoptotic cells-mimicking liposomes targeting macrophages [0.03%]
一种模拟凋亡细胞的脂质体靶向巨噬细胞的研究
Li Zhang,Yujiao Li,Xing Liu et al.
Li Zhang et al.
Macrophages are multifunctional innate immune cells that play indispensable roles in homeostasis, tissue repair, and immune regulation. However, dysregulated activation of macrophages is implicated in the pathogenesis of various human disor...
Stepwise-targeting and hypoxia-responsive liposome AMVY@NPs carrying siYAP and verteporfin for glioblastoma therapy [0.03%]
用于胶质母细胞瘤治疗的siYAP和verteporfin负载型逐步靶向及缺氧响应型脂质体AMVY@NPs
Ji Qi,Long Zhang,Zhongyu Ren et al.
Ji Qi et al.
Background: The Hippo pathway is a conserved tumour suppressor signalling pathway, and its dysregulation is often associated with abnormal cell growth and tumorigenesis. We previously revealed that the transcriptional coa...
Targeted pathophysiological treatment of ischemic stroke using nanoparticle-based drug delivery system [0.03%]
基于纳米颗粒的药物递送系统在缺血性卒中病理生理治疗中的靶向作用
Wei Liu,Lubin Liu,Hong Li et al.
Wei Liu et al.
Ischemic stroke poses significant challenges in terms of mortality and disability rates globally. A key obstacle to the successful treatment of ischemic stroke lies in the limited efficacy of administering therapeutic agents. Leveraging the...
Ambient energy harvesters in wearable electronics: fundamentals, methodologies, and applications [0.03%]
能量收集在可穿戴电子产品中的应用:基础,方法和应用
Ruoyao Yu,Shaoqing Feng,Qingwen Sun et al.
Ruoyao Yu et al.
In recent years, wearable sensor devices with exceptional portability and the ability to continuously monitor physiological signals in real time have played increasingly prominent roles in the fields of disease diagnosis and health manageme...
A thermo-sensitive hydrogel with prominent hemostatic effect prevents tumor recurrence via anti-anoikis-resistance [0.03%]
一种具有显著止血效果的热敏水凝胶可通过抗 anoikis 耐受性预防肿瘤复发
Yang Liu,Lei Ding,Gaojie Chen et al.
Yang Liu et al.
Tumor cells can survive when detached from the extracellular matrix (ECM) or lose cell-cell connections, a phenomenon known as anoikis-resistance (AR). AR is closely associated with tumor cell metastasis and recurrence, enabling tumor cells...
Bio-inspired biorthogonal compartmental microparticles for tumor chemotherapy and photothermal therapy [0.03%]
一种用于肿瘤化疗和光热治疗的仿生双正交微粒及其制备方法
Qingfei Zhang,Gaizhen Kuang,Li Wang et al.
Qingfei Zhang et al.
Microcarrier is a promising drug delivery system demonstrating significant value in treating cancers. One of the main goals is to devise microcarriers with ingenious structures and functions to achieve better therapeutic efficacy in tumors....