Enhanced brightness and photostability of dye-sensitized Nd-doped rare earth nanocomposite for in vivo NIR-IIb vascular and orthotopic tumor imaging [0.03%]
用于体内NIR-IIb血管和原位肿瘤成像的敏化Nd掺杂稀土纳米复合材料的增强亮度和光稳定性
Syue-Liang Lin,Shih-Po Su,Yuan-Zhen Yang et al.
Syue-Liang Lin et al.
Rare-earth doped nanoparticles (RENPs) have shown promise in biomedical imaging, particularly within the NIR-IIb region, due to their deep tissue penetration and minimal light scattering. However, challenges such as low extinction coefficie...
Synergistic strategies for glioblastoma treatment: CRISPR-based multigene editing combined with immune checkpoint blockade [0.03%]
胶质母细胞瘤的协同治疗策略：结合免疫检查点抑制的CRISPR多基因编辑疗法
Xiaolin Liu,Xiao Liu,Xiaonan Luo et al.
Xiaolin Liu et al.
Glioblastoma (GBM) is a primary brain tumor known for its high levels of aggressiveness and resistance to current treatments such as radiotherapy and chemotherapy. As a result, there is a pressing need for innovative therapeutic approaches ...
Nano-delivery platform with strong protection and efficient delivery: preparation of self-assembled RNA pesticide with dual RNAi targets against Apolygus lucorum [0.03%]
具有强保护和高效递送的纳米递药平台：用于同时靶向Apolygus lucorum的双链RNA农药自组装体系构建
Heng Qiao,Qinhong Jiang,Jing Zhao et al.
Heng Qiao et al.
Background: RNA pesticide is regarded as the "third revolution in the history of pesticides". However, the double-stranded RNA (dsRNA) is easily degraded in the environment, and its delivery efficiency is not sufficient f...
A systematic review of nanocarriers used in medicine and beyond - definition and categorization framework [0.03%]
纳米载体在医学等领域中的应用及其定义和分类框架的系统性综述研究
Sabine Gressler,Christina Hipfinger,Florian Part et al.
Sabine Gressler et al.
Nanocarriers are transport and encapsulation systems that primarily serve to protect and improve the dispersibility of predominantly hydrophobic active ingredients but also enable their targeted delivery and controlled release at the site o...
Hyaluronic acid-curcumin nanoparticles for preventing the progression of experimental autoimmune uveitis through the Keap1/Nrf2/HO-1 signaling pathway [0.03%]
透明质酸-姜黄素纳米粒通过Keap1/Nrf2/HO-1信号通路抑制实验性自身免疫葡萄膜炎进展
Weiwei Tang,Xiaomin Huang,Yun-Di Yi et al.
Weiwei Tang et al.
Globally, uveitis is a collection of intraocular inflammatory disorders that affect mainly the uvea, resulting in irreversible blindness and a heavy socioeconomic burden. Excessive autoimmune inflammation and oxidative stress are major driv...
Unveiling the new chapter in nanobody engineering: advances in traditional construction and AI-driven optimization [0.03%]
纳米体工程新纪元：传统构建与AI驱动优化的进展
Jiwei Liu,Lei Wu,Anqi Xie et al.
Jiwei Liu et al.
Nanobodies (Nbs), miniature antibodies consisting solely of the variable region of heavy chains, exhibit unique properties such as small size, high stability, and strong specificity, making them highly promising for disease diagnosis and tr...
Innovative nanoparticle-based approaches for modulating neutrophil extracellular traps in diseases: from mechanisms to therapeutics [0.03%]
基于纳米粒子调节疾病中中性粒细胞胞外诱捕网的创新方法：从机制到治疗
Haisong Li,Can Li,Cong Fu et al.
Haisong Li et al.
Neutrophil extracellular traps (NETs) participate in both host defense and the pathogenesis of various diseases, such as infections, thrombosis, and tumors. While they help capture and eliminate pathogens, NETs' excessive or dysregulated fo...
Supramolecular interactions-driven aggregation to prepare lipoic acid-bioadhesives for seawater-immersed wounds [0.03%]
一种超分子相互作用驱动的脂酸水凝胶创面敷料用于海水浸泡伤口修复
Rui Lei,Wenjun Wang,Guan Li et al.
Rui Lei et al.
Seawater-immersed wounds can be threatened by high pH, high permeability and infection, which may lead to the development of chronic wounds. The present study develops an aggregation strategy for the rapid preparation of α-lipoic acid (LA)...
Overcoming hypoxia-induced breast cancer drug resistance: a novel strategy using hollow gold-platinum bimetallic nanoshells [0.03%]
克服缺氧诱导的乳腺癌药物耐受性的新策略——采用空心金铂纳米壳的新方法
Lian-Ying Zhang,Xiao-Tong Chen,Rong-Tian Li et al.
Lian-Ying Zhang et al.
Breast cancer (BC) is a significant cause of cancer-related deaths among women worldwide. Hypoxia, a common feature of solid tumor, is associated with drug resistance and a poor prognosis in BC. In this study, we present a strategy to overc...
Correction: Multifunctional nanobubbles carrying indocyanine green and paclitaxel for molecular imaging and the treatment of prostate cancer [0.03%]
携带吲哚菁绿和紫杉醇的多功能纳米气泡用于分子影像和前列腺癌治疗（纠错）
Minmin Lan,Lianhua Zhu,Yixuan Wang et al.
Minmin Lan et al.
Published Erratum
Journal of nanobiotechnology. 2025 Feb 6;23(1):84. DOI:10.1186/s12951-025-03174-8 2025