Harnessing the nutriceutics in early-stage breast cancer: mechanisms, combinational therapy, and drug delivery [0.03%]
营养素在早期内乳腺癌中的作用：机制、联合治疗和药物递送
Pavithra Pradeep Prabhu,Barsha Mohanty,Cynthia Lizzie Lobo et al.
Pavithra Pradeep Prabhu et al.
Background: Breast cancer (BC) is a significant health challenge, ranking as the second leading cause of cancer-related death and the primary cause of mortality among women aged 45 to 55. Early detection is crucial for op...
Brain-on-a-chip: an emerging platform for studying the nanotechnology-biology interface for neurodegenerative disorders [0.03%]
神经系统变性疾病研究中新兴的纳米技术-生物学界面的研究平台：芯片式脑组织模型
Raquel O Rodrigues,Su-Ryon Shin,Manuel Bañobre-López
Raquel O Rodrigues
Neurological disorders have for a long time been a global challenge dismissed by drug companies, especially due to the low efficiency of most therapeutic compounds to cross the brain capillary wall, that forms the blood-brain barrier (BBB) ...
Correction: Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy [0.03%]
纠正：冷暴露诱导的血浆外泌体通过抑制自噬减少骨量
Li-Min Lei,Fu-Xing-Zi Li,Xiao Lin et al.
Li-Min Lei et al.
Published Erratum
Journal of nanobiotechnology. 2024 Sep 18;22(1):572. DOI:10.1186/s12951-024-02834-5 2024
New insights into allergic rhinitis treatment: MSC nanovesicles targeting dendritic cells [0.03%]
过敏性鼻炎治疗新见解：靶向树突状细胞的间充质干细胞纳米囊泡
Jianyu Liu,Meiqun Wang,Xiaoyan Tian et al.
Jianyu Liu et al.
Allergic rhinitis (AR) is a condition with limited treatment options. This study investigates the potential use of mesenchymal stem cell (MSC) nanovesicles as a novel therapy for AR. Specifically, the study explores the underlying mechanism...
Thermosensitive hydrogel as a sustained release carrier for mesenchymal stem cell-derived extracellular vesicles in the treatment of intrauterine adhesion [0.03%]
温敏水凝胶作为间充质干细胞源外泌体治疗宫腔粘连的缓释载体
Shujun Yu,Xinru Zhang,Wenwen Li et al.
Shujun Yu et al.
Intrauterine adhesion (IUA), a prevalent etiology of female infertility, is attributed to endometrial damage. However, conventional therapeutic interventions for IUA are plagued by high recurrence rates. Human umbilical cord mesenchymal ste...
The progress and future of the treatment of Candida albicans infections based on nanotechnology [0.03%]
基于纳米技术的白色念珠菌感染诊疗研究进展与展望
Yang Gao,Qinyan Cao,Yuyang Xiao et al.
Yang Gao et al.
Systemic infection with Candida albicans poses a significant risk for people with weakened immune systems and carries a mortality rate of up to 60%. However, current therapeutic options have several limitations, including increasing drug to...
The biomedical applications of nanozymes in orthopaedics based on regulating reactive oxygen species [0.03%]
基于调节活性氧的纳米酶在骨科的生物医学应用
Xiangcheng Gao,Jiejie Zhang,Yining Gong et al.
Xiangcheng Gao et al.
Nanozymes, a category of nanomaterials with enzyme-like activity, have garnered growing interest in various biomedical contexts. Notably, nanozymes that are capable of regulating reactive oxygen species levels by emulating antioxidant or pr...
Umbilical cord blood-derived exosomes attenuate dopaminergic neuron damage of Parkinson's disease mouse model [0.03%]
人胎盘和脐带血来源的外泌体对帕金森病小鼠模型多巴胺能神经元损伤的保护作用及机制研究
Junjie Ye,Xiaodong Sun,Qi Jiang et al.
Junjie Ye et al.
Background: Umbilical cord blood (UCB) is a rich source of multifunctional stem cells characterized by low immunogenicity. Recent research in the fields of aging and regenerative medicine has revealed the potential of hum...
Transformable self-delivered supramolecular nanomaterials combined with anti-PD-1 antibodies alleviate tumor immunosuppression to treat breast cancer with bone metastasis [0.03%]
可变形自我递送的超分子纳米材料结合抗PD-1抗体缓解免疫抑制治疗骨转移性乳腺癌
Xueying Liu,Hao Wang,Zhaofeng Li et al.
Xueying Liu et al.
Breast cancer is the most common malignant tumor that threatens women's life and health, and metastasis often occurs in the advanced stage of breast cancer, leading to pathological bone destruction and seriously reducing patient quality of ...
A nanobody-guided multifunctional T cell engager promotes strong anti-tumor responses via synergistic immuno-photothermal effects [0.03%]
一种纳米抗体引导的多功能T细胞结合剂可通过协同免疫光热效应促进强大的抗肿瘤反应
Shenxia Xie,Wei Shi,Siliang Duan et al.
Shenxia Xie et al.
Background: T cell-based immunotherapies are facing great challenges in the recruitment and activation of tumor-specific T cells against solid tumors. Among which, utilizing nanobody (Nb) or nanobodies (Nbs) to construct ...