Cascade-recharged macrophage-biomimetic ruthenium-based nanobattery for enhanced photodynamic-induced immunotherapy [0.03%]
级联式宏噬细胞仿生钌基纳米电池用于增强光动力免疫治疗
Guoyu Xia,Zhongxiong Fan,Qingluo Wang et al.
Guoyu Xia et al.
Photodynamic-induced immunotherapy (PDI) is often hampered by low reactive oxygen species (ROS) yield, intra-tumor hypoxia, high glutathione (GSH) concentration, and immunosuppressive microenvironment. In view of this, a ruthenium (Ru)-base...
Infertility treatment using polysaccharides-based hydrogels: new strategies in tissue engineering and regenerative medicine [0.03%]
使用多糖水凝胶进行不孕症治疗：组织工程和再生医学的新策略
Maryam Ghahremani-Nasab,Soraya Babaie,Sara Bazdar et al.
Maryam Ghahremani-Nasab et al.
Infertility is a primary health issue affecting about 15% of couples of reproductive ages worldwide, leading to physical, mental, and social challenges. Advances in nanobiotechnology and regenerative medicine are opening new therapeutic hor...
Specific muscle targeted delivery of miR-130a loaded lipid nanoparticles: a novel approach to inhibit lipid accumulation in skeletal muscle and obesity [0.03%]
负载miR-130a的脂质纳米颗粒靶向特定肌肉传递：一种新颖的抑制骨骼肌中脂质积累和肥胖的方法
Yingqian Wang,Zeqiang Ma,Lehua Jiang et al.
Yingqian Wang et al.
Background: Skeletal muscle lipid deposition is a key manifestation of obesity, often accompanied by decreased exercise capacity and muscle atrophy. Skeletal muscle as the largest organ in the body, makes it challenges fo...
Multidimensional applications of prussian blue-based nanoparticles in cancer immunotherapy [0.03%]
普鲁士蓝基纳米颗粒在癌症免疫治疗中的多维应用
Jiayi Zhang,Fang Wang,Zhaogang Sun et al.
Jiayi Zhang et al.
Immunotherapy holds notable progress in the treatment of cancer. However, the clinical therapeutic effect remains a significant challenge due to immune-related side effects, poor immunogenicity, and immunosuppressive microenvironment. Nanop...
Conditioning period impacts the morphology and proliferative effect of extracellular vesicles derived from rat adipose tissue derived stromal cell [0.03%]
条件培养期对大鼠脂肪间充质干细胞来源的细胞外囊泡形态及增殖效果的影响
Borger Anton,Haertinger Maximilian,Millesi Flavia et al.
Borger Anton et al.
A serum-free conditioning period is a crucial step during small extracellular vesicle (sEV) preparation ranging from 12 to 72h. There is a paucity of knowledge about downstream effects of serum-free conditioning on sEVs and the optimal dura...
3D printed porous magnesium metal scaffolds with bioactive coating for bone defect repair: enhancing angiogenesis and osteogenesis [0.03%]
具有生物活性涂层的3D打印多孔镁金属支架用于骨缺损修复：促进血管生成和成骨作用
Jianting Ye,Bozun Miao,Yingjie Xiong et al.
Jianting Ye et al.
In orthopedics, the effective treatment of bone defects remains a major challenge. Magnesium (Mg) metals, with their excellent biocompatibility and favorable osteoconductivity, osteoinductivity, and osseointegration properties, hold great p...
Exploring the link between M1 macrophages and EMT of amniotic epithelial cells: implications for premature rupture of membranes [0.03%]
M1型巨噬细胞和羊膜上皮细胞的EMT之间的联系的研究：对胎膜早破的意义
Yuhua Gao,Yanan Zhang,Ningning Mi et al.
Yuhua Gao et al.
Background: Despite increasing evidence supporting the role of an amniotic epithelial-mesenchymal transition (EMT) in the premature rupture of membranes (PROMs), it remains unclear if extracellular vesicle (EV) derived fr...
Nanomedicine's shining armor: understanding and leveraging the metal-phenolic networks [0.03%]
纳米医学的坚固护甲：了解和利用金属酚网络
Zhengming Tang,Zhijie Huang,Yisheng Huang et al.
Zhengming Tang et al.
Metal-phenolic networks (MPNs), which comprise supramolecular amorphous networks formed by interlinking polyphenols with metal ions, garner escalating interest within the realm of nanomedicine. Presently, a comprehensive synthesis of the cu...
Metal-organic framework-based smart stimuli-responsive drug delivery systems for cancer therapy: advances, challenges, and future perspectives [0.03%]
用于癌症治疗的基于金属有机框架的智能刺激响应药物递送系统：进展、挑战和未来展望
Ziliang Guo,Yuzhen Xiao,Wenting Wu et al.
Ziliang Guo et al.
Cancer treatment is currently one of the most critical healthcare issues globally. A well-designed drug delivery system can precisely target tumor tissues, improve efficacy, and reduce damage to normal tissues. Stimuli-responsive drug deliv...
Exosomal lncRNA Mir100hg from lung cancer stem cells activates H3K14 lactylation to enhance metastatic activity in non-stem lung cancer cells [0.03%]
肺癌干细胞中的exosomal lncRNA Mir100hg通过激活H3K14乳酰化来增强非干性肺癌细胞的转移活性
Lei Shi,Bowen Li,Jiyu Tan et al.
Lei Shi et al.
The mean survival of metastatic lung adenocarcinoma is less than 1 year, highlighting the urgent need to understand the mechanisms underlying its high mortality rate. The role of Extracellular vesicles (EVs) in facilitating the interactions...