Tetrahedral framework nucleic acids inhibit Aβ-mediated ferroptosis and ameliorate cognitive and synaptic impairments in Alzheimer's disease [0.03%]
四面体框架核酸抑制阿尔茨海默病中的Aβ介导的铁死亡及认知和突触损伤改善
Lu Tan,Jiazhao Xie,Chenqi Liao et al.
Lu Tan et al.
Background: Ferroptosis represents a nonapoptotic type of programmed cell death induced by excessive intracellular iron accumulation. Ferroptosis is an essential driver of the pathogenesis of Alzheimer's disease (AD). Tet...
IFITM1 is a host restriction factor that inhibits porcine epidemic diarrhea virus infection [0.03%]
IFITM1是抑制猪流行性腹泻病毒入侵的宿主限制因子
Jiahao Cheng,Jiayi He,Simeng Feng et al.
Jiahao Cheng et al.
Background: Porcine epidemic diarrhea virus (PEDV) infection and transmission pose a serious threat to the global swine industry. The search for a new host factor with anti-PEDV effect may be an effective potential target...
Recent advances of photoresponsive nanomaterials for diagnosis and treatment of acute kidney injury [0.03%]
用于急性肾损伤诊断和治疗的光响应纳米材料的研究进展
Shijie Yao,Yinan Wang,Xiaozhou Mou et al.
Shijie Yao et al.
Non-invasive imaging in the near-infrared region (NIR) offers enhanced tissue penetration, reduced spontaneous fluorescence of biological tissues, and improved signal-to-noise ratio (SNR), rendering it more suitable for in vivo deep tissue ...
A magnetic epitope-imprinted microsphere used for selective separation and rapid detection of SHV-type β-lactamases in bacteria: a novel strategy of antimicrobial resistance detection [0.03%]
一种用于选择性分离和快速检测细菌中SHV型β-内酰胺酶的磁性表位印迹微球：一种新的抗菌药物耐药性检测策略
Yusun Zhou,Kunqi Wang,Lele Li et al.
Yusun Zhou et al.
Background: The production of β-lactamases is the most prevalent resistance mechanism for β-lactam antibiotics in Gram-negative bacteria. Presently, over 4900 β-lactamases have been discovered, and they are categorized...
High-throughput synthesis and optimization of ionizable lipids through A3 coupling for efficient mRNA delivery [0.03%]
基于A3连接的手性离子化脂质的高通量合成和优化及其在mRNA递送中的应用
Jingjiao Li,Jie Hu,Danni Jin et al.
Jingjiao Li et al.
Background: The efficacy of mRNA-based vaccines and therapies relies on lipid nanoparticles (LNPs) as carriers to deliver mRNA into cells. The chemical structure of ionizable lipids (ILs) within LNPs is crucial in determi...
Retraction Note: A pH/enzyme dual responsive PMB spatiotemporal release hydrogel promoting chronic wound repair [0.03%]
撤稿说明：一种pH/酶双重响应的PMB时空释放水凝胶促进慢性伤口愈合
Lanlan Dong,Can Huang,Baohua Zhao et al.
Lanlan Dong et al.
Retraction of Publication
Journal of nanobiotechnology. 2024 Nov 5;22(1):675. DOI:10.1186/s12951-024-02960-0 2024
Nitric oxide-based multi-synergistic nanomedicine: an emerging therapeutic for anticancer [0.03%]
基于一氧化氮的多协同纳米药物：一种抗肿瘤新疗法
Yaqin Tang,Qiyu Li,Ziwei Zhou et al.
Yaqin Tang et al.
Gas therapy has emerged as a promising approach for treating cancer, with gases like NO, H2S, and CO showing positive effects. Among these, NO is considered a key gas molecule with significant potential in stopping cancer progression. Howev...
MSC-microvesicles protect cartilage from degradation in early rheumatoid arthritis via immunoregulation [0.03%]
MSC微囊通过免疫调节在早期类风湿关节炎中保护软骨免于退化
Shixiong Wei,Rui-Juan Cheng,Sujia Li et al.
Shixiong Wei et al.
Objective: As research into preclinical rheumatoid arthritis (pre-RA) has advanced, a growing body of evidence suggests that abnormalities in RA-affected joint cartilage precede the onset of arthritis. Thus, early prevent...
Magnetic 3D macroporous MOF oriented urinary exosome metabolomics for early diagnosis of bladder cancer [0.03%]
磁性三维宏观孔MOFs用于尿外泌体代谢组学以实现膀胱癌的早期诊断
Yiqing Cao,Jianan Feng,Qiao Zhang et al.
Yiqing Cao et al.
Bladder cancer (BCa) exhibits the escalating incidence and mortality due to the untimely and inaccurate early diagnosis. Urinary exosome metabolites, carrying critical tumor cell information and directly related to bladder, emerge as promis...
Intestinal nanoparticle delivery and cellular response: a review of the bidirectional nanoparticle-cell interplay in mucosa based on physiochemical properties [0.03%]
肠道纳米药物递送及细胞响应：基于理化性质的双向纳米粒子-细胞相互作用在黏膜中的综述研究
Yu Wang,Yilei Mo,Yingwei Sun et al.
Yu Wang et al.
Orally administered nanocarriers play an important role in improving druggability, promoting intestinal absorption, and enhancing therapeutic applications for the treatment of local and systemic diseases. However, the delivering efficiency ...