Correction: Nanoliposomal PD-1 antagonist target tumor-draining lymph nodes to revitalize T cells and improve anti-tumor effect in hepatocellular carcinoma [0.03%]
纠正:纳米脂质体PD-1拮抗剂靶向肿瘤引流淋巴结以激活T细胞并改善肝癌的抗肿瘤作用
Wanyue Cao,Kai Yang,Gaowei Jin et al.
Wanyue Cao et al.
Published Erratum
Journal of nanobiotechnology. 2025 Oct 10;23(1):642. DOI:10.1186/s12951-025-03699-y 2025
Microneedles combining delivery of hUMSC-derived exosomes and EGCG mitigate UV-induced skin damage [0.03%]
结合hUMSC衍生的外泌体和EGCG递送的微针可减轻紫外线引起的皮肤损伤
Chenhui He,Zeqian Wang,Zhaoting Jiang et al.
Chenhui He et al.
Exposure to ultraviolet (UV) radiation compromises both the aesthetic and functional properties of the skin, accelerates aging, increases the risk of skin cancer, and significantly impairs quality of life. Exosomes derived from human umbili...
Orally ingested nanosilica causes liver-specific accumulation and induces liver senescence and fibrosis via the microbiota-gut-liver axis [0.03%]
口服摄入的纳米级二氧化硅通过微生物群-肠-肝轴引起肝脏特异性蓄积并诱导肝衰老和纤维化
Xiaofei Han,Lisha Du,Yanjie Dou et al.
Xiaofei Han et al.
Background: The increased use of nanosilica (SiO2 NPs) poses a safety risk to public health. Current research on the tissue distribution and microbiota-gut-liver crosstalk toxicity of orally ingested SiO2 NPs remains poor...
Porphyromonas gingivalis extracellular vesicles exacerbated osteoporosis by disrupting osteoblast mitochondrial dynamics and inhibiting Cpt2-regulated fatty acid oxidation [0.03%]
牙龈卟啉单胞菌细胞外囊泡通过破坏成骨细胞线粒体动力学并抑制肉碱棕榈酰转移酶2介导的脂肪酸氧化来加重骨质疏松症
Qiujing Qiu,Xiaoyuan Yan,Zeying Zhang et al.
Qiujing Qiu et al.
Background: Recent studies have implicated periodontitis (PD) as a potential risk factor for osteoporosis; however, the precise mechanisms remain unclear. Porphyromonas gingivalis (Pg), a key pathogen associated with PD, ...
Engineered exosomes conferred with ROS-regulation and immuno-suppression for ameliorating lupus nephritis [0.03%]
ROS调控和免疫抑制工程外泌体改善狼疮性肾炎
Jiang Tian,Zexin Wang,Zhicheng Tang et al.
Jiang Tian et al.
Mesenchymal stromal cell-derived exosomes (MEXs) possess inherent homing capabilities, tissue repair abilities, and anti-inflammatory and immunomodulatory functions, making them a promising alternative for treating lupus nephritis (LN). In ...
Yawen Zhu,Wanqi Yang,Zhongxia Wang et al.
Yawen Zhu et al.
Liver regeneration is a sophisticated biological process influenced by a complex microenvironment that becomes profoundly altered in various pathological conditions. Current therapeutic approaches, including liver transplantation and pharma...
Targeting JAK2 with a multifunctional nanoinhibitor for long-lasting anti-inflammatory effects and bone repair [0.03%]
靶向JAK2的多功能纳米抑制剂用于长期抗炎和骨修复
Yang Liu,Duan Wang,Wenqian Zheng et al.
Yang Liu et al.
Dysregulation of the JAK2/STAT3 pathway disrupts immune balance and tissue homeostasis, leading to persistent inflammation and subsequent bone loss. Yet, commonly used JAK2 inhibitors with hydrophobicity primarily suppress inflammation but ...
Lipid-based nanoparticles external triggered release strategies in cancer nanomedicine [0.03%]
癌症纳米医学中基于脂质的纳米颗粒外部触发释放策略
Abdulaziz Alhussan,Louise Ho,Yao Zhang et al.
Abdulaziz Alhussan et al.
Nearly half of humanity will develop cancer in their Lifetime. Current therapies, particularly chemotherapeutic drugs, face significant challenges due to the lack of tissue-specific delivery. For example, less than 0.1% of anticancer drugs ...
Manganese-loaded carbon nanoparticles ameliorate ANCA-associated vasculitis by inhibiting ferroptosis [0.03%]
负载锰的碳纳米颗粒通过抑制铁死亡改善ANCA相关性血管炎
Yiru Wang,Yongman Lv,Chengcheng Fu et al.
Yiru Wang et al.
Antineutrophil cytoplasmic antibody-associated glomerulonephritis (ANCA-GN), a life-threatening vasculitis manifestation, involves systemic endothelial injury and rapid renal decline. Despite limited therapies, the role of ferroptosis, a ne...
Multifunctional nanoparticles in abdominal aortic aneurysm management: from basic research to clinical transformation [0.03%]
多功能纳米颗粒在腹主动脉瘤管理中的应用:从基础研究到临床转化
Gang Yuan,Weiming Wang,Xiaohui Jia et al.
Gang Yuan et al.
Abdominal aortic aneurysm (AAA) is a life-threatening vascular condition marked by localized aortic dilation and structural weakening of the vessel wall, often leading to catastrophic complications such as rupture. As one of the leading cau...