Preferential activation of type I interferon-mediated antitumor inflammatory signaling by CuS/MnO2/diAMP nanoparticles enhances anti-PD-1 therapy for sporadic colorectal cancer [0.03%]
CuS/MnO2/二腺苷5′-甲基焦磷酸纳米颗粒优先激活I型干扰素介导的抗肿瘤炎症信号轴，增强抗PD-1疗法治疗偶发性结直肠癌的功效
Jinrong Peng,Qian Yang,Rong Lei et al.
Jinrong Peng et al.
Converting the "cold" tumor microenvironment (TME) to a "hot" milieu has become the prevailing approach for enhancing the response of immune-excluded/immunosuppressed colorectal cancer (CRC) patients to immune checkpoint blockade (ICB) ther...
Correction: Conformal immunomodulatory hydrogels for the treatment of otitis media [0.03%]
纠正：用于治疗中耳炎的共形免疫调节水凝胶
Yuefan Jin,Yueyi Shang,Cuiping Wu et al.
Yuefan Jin et al.
Published Erratum
Journal of nanobiotechnology. 2024 Nov 11;22(1):695. DOI:10.1186/s12951-024-02959-7 2024
Living photosynthetic microneedle patches for in situ oxygenation and postsurgical melanoma therapy [0.03%]
用于原位供氧和术后黑色素瘤治疗的活光合作用微针贴片
Jinxuan Jia,Xuhong Guo,Yuwei Wang et al.
Jinxuan Jia et al.
Surgical excision remains the principal treatment for melanoma, while tumor recurrence and delayed wound healing often occur due to the residual tumor cells and hypoxic microenvironment in the postoperative skin wounds. Herein, we present a...
Probiotic-derived extracellular vesicles alleviate AFB1-induced intestinal injury by modulating the gut microbiota and AHR activation [0.03%]
益生菌源性细胞外囊泡通过调节肠道微生物群和AHR活化缓解黄曲霉毒素B1致肠损伤
Jinyan Li,Mengdie Shi,Yubo Wang et al.
Jinyan Li et al.
Background: Aflatoxin B1 (AFB1) is a mycotoxin that widely found in the environment and mouldy foods. AFB1 initially targets the intestine, and AFB1-induced intestinal injury cannot be ignored. Lactobacillus amylovorus (L...
GelMA hydrogels reinforced by PCL@GelMA nanofibers and bioactive glass induce bone regeneration in critical size cranial defects [0.03%]
聚己内酯@明胶美徳海绵纳米纤维和生物活性玻璃增强的明胶美德海绵水凝胶促进颅骨缺损修复
Chenghao Yu,Jinli Chen,Tianrui Wang et al.
Chenghao Yu et al.
Background: The process of bone healing is complex and involves the participation of osteogenic stem cells, extracellular matrix, and angiogenesis. The advancement of bone regeneration materials provides a promising oppor...
Silver nanoparticle induced immunogenic cell death can improve immunotherapy [0.03%]
银纳米颗粒诱导的免疫原性细胞死亡可以改善免疫治疗
Ara Sargsian,Xanthippi Koutsoumpou,Hermon Girmatsion et al.
Ara Sargsian et al.
Cancer immunotherapy is often hindered by an immunosuppressive tumor microenvironment (TME). Various strategies are being evaluated to shift the TME from an immunologically 'cold' to 'hot' tumor and hereby improve current immune checkpoint ...
Nanocarriers for intracellular delivery of proteins in biomedical applications: strategies and recent advances [0.03%]
生物医学应用中的蛋白类药物细胞内递送纳米载体：策略与最新研究进展
Chuanda Zhu,Jing Mu,Ling Liang
Chuanda Zhu
Protein drugs are of great importance in maintaining the normal functioning of living organisms. Indeed, they have been instrumental in combating tumors and genetic diseases for decades. Among these pharmaceutical agents, those that target ...
Correction: Preparation and characterization of BSA‑loaded liraglutide and platelet fragment nanoparticle delivery system for the treatment of diabetic atherosclerosis [0.03%]
订正：用于治疗糖尿病动脉粥样硬化的载BSA的利拉鲁肽和血小板片段纳米颗粒递送系统的制备及表征
Mingping He,Ming Fang,Limin Fan et al.
Mingping He et al.
Published Erratum
Journal of nanobiotechnology. 2024 Nov 10;22(1):693. DOI:10.1186/s12951-024-02947-x 2024
Genetically modified E. Coli secreting melanin (E.melanin) activates the astrocytic PSAP-GPR37L1 pathway and mitigates the pathogenesis of Parkinson's disease [0.03%]
分泌黑色素的大肠杆菌(E.melanin)激活星形胶质细胞PSAP-GPR37L1通路并缓解帕金森病病理症状
Weixian Kong,Yu Liu,Pu Ai et al.
Weixian Kong et al.
The characteristic neuropathology of Parkinson's disease (PD) involves the abnormal accumulation of phosphorylated α-synuclein (αSyn), as well as a significant decrease in neuromelanin (NM) levels within dopamine neurons (DaNs). Unlike α...
A collagenase-decorated Cu-based nanotheranostics: remodeling extracellular matrix for optimizing cuproptosis and MRI in pancreatic ductal adenocarcinoma [0.03%]
一种胶原酶修饰的铜基纳米诊疗剂：重塑胰腺导管腺癌的细胞外基质以优化铜死亡和MRI
Yining Wang,Qiaomei Zhou,Wangping Luo et al.
Yining Wang et al.
Pancreatic ductal adenocarcinoma (PDAC), characterized by a dense extracellular matrix (ECM), presents significant therapeutic challenges due to its poor prognosis and high resistance to chemotherapy. Current chemodrugs and diagnostic agent...