Qinze Rong,Zibin Chu,Ye Xu et al.
Qinze Rong et al.
Nucleic acid nanotechnology (NAN) has emerged as a powerful platform for constructing programmable molecular architectures, with broad applications spanning biomedicine, materials science, and molecular computing. While numerous reviews hav...
Structurally and functionally optimized silk fibroin-alginate-based biomimetic scaffolds reinforced with nanobioceramics for bone tissue engineering applications [0.03%]
结构和功能最佳化的丝素-海藻酸盐仿生骨支架用于骨组织工程中
Thanh-Mai Ngoc Nguyen,Ngoc-Han Hoai Le,Mohanapriya Murugesan et al.
Thanh-Mai Ngoc Nguyen et al.
In this study, we prepared chemically crosslinked silk fibroin (SF) and sodium alginate (Alg) biomimetic scaffolds reinforced with bioceramic nanohydroxyapatite (nHAp) for bone tissue engineering (BTE) applications. The pore sizes of these ...
Correction: NIR-responsive Cu2-xSe@Fc nanoparticles for photothermal- ferroptosis combination therapy in esophageal cancer [0.03%]
纠正：用于食道癌光热-铁死亡联合治疗的近红外响应Cu2-xSe@Fc纳米粒子
Linlin Shi,Ying Yu,Jiayi Li et al.
Linlin Shi et al.
Published Erratum
Journal of nanobiotechnology. 2025 Dec 2;23(1):753. DOI:10.1186/s12951-025-03809-w 2025
Growth hormone-releasing peptide 6 (GHRP-6) hydrogel for acute kidney injury therapy via metabolic regulation [0.03%]
代谢调节急性肾损伤治疗用生长激素释放肽6（GHRP-6）水凝胶
Xiaotong Zhao,Kai Pan,Rui Li et al.
Xiaotong Zhao et al.
Renal tubular epithelial cells (TECs), which are highly susceptible to injury during acute kidney injury (AKI), have notable regenerative effects on renal recovery after AKI. AKI-driven metabolic reprogramming of TECs plays a critical role ...
3D dynamic magnetic microfluidic chip for efficient plasma extracellular vesicle enrichment and machine learning-based multiparametric diagnosis of hepatocellular carcinoma [0.03%]
一种高效的三维磁性微流控芯片及其结合机器学习的肝癌多参数诊断方法
Xiaodan Xi,Kezhen Yi,Lili Xu et al.
Xiaodan Xi et al.
Background: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide, with early diagnosis critical for improving outcomes. Current diagnostic tools, including serum biomarkers and...
Meta-surface plasmon resonance microscopy for sensitive, high-throughput, and long-term label-free analysis of cell adhesion dynamics [0.03%]
用于细胞粘附动力学敏感、高通量和长期无标签分析的元表面等离激元共振显微镜
Mingqian Chen,Wen Li,Taoyu Hu et al.
Mingqian Chen et al.
Quantitative, label-free monitoring of dynamic cell adhesion remains challenging. Meta-Surface Plasmon Resonance Microscopy (Meta-SPRM) is a novel platform integrating bright-field microscopy with engineered Meta-SPR nanocup arrays. This sy...
Cu2+-doped Hollow Ca2+-polyphenol nano-therapeutics for overcoming multidrug-resistant bacteria-induced infections [0.03%]
用于克服多药耐药细菌引起的感染的Cu2+掺杂空心Ca2 + -聚酚纳米疗法
Yueyang Zhong,Wenjie Fan,Yue Huang et al.
Yueyang Zhong et al.
The abuse of antibiotics has accelerated the emergence of multidrug-resistant (MDR) bacterial strains, while the development of novel antibiotics has failed to keep pace with the evolution of bacteria. Consequently, there is an urgent need ...
Astaxanthin and Dihydroartemisinin loaded PLGA NPs for atherosclerosis therapy via regulating lipid metabolism and immune microenvironment [0.03%]
载有虾青素和二氢青蒿素的PLGA纳米粒通过调节脂质代谢和免疫微环境用于动脉粥样硬化治疗
Jiayao Hu,Hao Liu,Yizhou Wu et al.
Jiayao Hu et al.
The active ingredients of Traditional Chinese Medicine with diverse structures exhibited anti-inflammatory and lipid lowering functions, demonstrating significant therapeutic effects in inflammatory diseases of atherosclerosis. We incorpora...
MXene-integrated microneedles reprogram diabetic-associated macrophages for deep-wound infection therapy and immunoprotection [0.03%]
MXene集成的微针可重新编程糖尿病相关巨噬细胞用于深度伤口感染治疗和免疫保护
Wenshuai Li,Lulu Wang,Hui Zhao et al.
Wenshuai Li et al.
Traditional hyperthermia-boosted photothermal therapy (PTT) for infected wounds often suffers from thermal damage to healthy tissue, exacerbates immune dysregulation, and compromises antibacterial efficacy in deep tissue. Here, we developed...
Delivery of miR-29a/29c-3p by serum exosomes promotes osteogenesis through TET3-dependent Sox9 demethylation and PI3K/Akt activation [0.03%]
血清外泌体递送miR-29a/29c-3p通过TET3依赖的Sox9去甲基化和激活PI3K/Akt促进成骨作用
Qing Lin,Weipeng Sun,Biyi Zhao et al.
Qing Lin et al.
Osteoporosis (OP) is characterized by impaired bone formation, largely attributed to dysfunctional osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Circulating factors, particularly exosomes acting as natural nanoca...