Integrating electrospun aligned fiber scaffolds with bovine serum albumin-basic fibroblast growth factor nanoparticles to promote tendon regeneration [0.03%]
融合型静电纺丝齐轴纤维支架及牛血清白蛋白-碱性成纤维细胞生长因子纳米颗粒促进肌腱再生的研究
Yuwan Li,Zhen Ge,Ziming Liu et al.
Yuwan Li et al.
Background: Electrospun nanofiber scaffolds have been widely used in tissue engineering because they can mimic extracellular matrix-like structures and offer advantages including high porosity, large specific surface area...
PDGFR-α shRNA-polyplex for uveal melanoma treatment via EMT mediated vasculogenic mimicry interfering [0.03%]
通过EMT介导的血管生成模拟干扰进行脉络膜黑色素瘤治疗的PDGFR-α shRNA-聚复合物
Jiahao Wang,Zhirong Chen,Peiyi Zhao et al.
Jiahao Wang et al.
Up to 50% of individuals with uveal melanoma (UM), a frequent cancer of the eye, pass away from metastases. One of the major challenges in treating UM is the role of receptor tyrosine kinases (RTKs), which mediate the epithelial-mesenchymal...
Spatiotemporal-controllable ROS-responsive camptothecin nano-bomb for chemo/photo/immunotherapy in triple-negative breast cancer [0.03%]
可控型ROS响应性喜树碱纳米炸弹用于三阴乳腺癌的化疗/光动力免疫联合治疗研究
Wenjie Xu,Zhaokui Zeng,Yucheng Tang et al.
Wenjie Xu et al.
Chemotherapy is still one of the major approaches in triple-negative breast cancer (TNBC) treatment. The development of new formulations for classic chemotherapeutic drugs remains interests in studies. Camptothecin (CPT) is powerful antitum...
Unveiling the molecular blueprint of SKP-SCs-mediated tissue engineering-enhanced neuroregeneration [0.03%]
揭示SKP-SCs介导的组织工程增强神经再生的分子蓝图
Hui Zhu,Ying Wang,Siyuan Xu et al.
Hui Zhu et al.
Peripheral nerve injury poses a significant challenge to the nervous system's regenerative capacity. We previously described a novel approach to construct a chitosan/silk fibroin nerve graft with skin-derived precursor-induced Schwann cells...
Natural epigallocatechin-3-gallocarboxylate nanoformulation loaded doxorubicin to construct a novel and low cardiotoxicity chemotherapeutic drug for high-efficiency breast cancer therapy [0.03%]
一种新型低心脏毒性的高效治疗乳腺癌的化疗药物——用天然儿茶素纳米载体负载阿霉素制备多功能抗癌药研究
Ke Wang,Siqi Geng,Fang Wang et al.
Ke Wang et al.
Anthracycline doxorubicin (DOX) remains the first-line chemotherapeutic drug for the efficient treatment of breast cancer, but its severe cardiotoxicity limits its long-term application in clinical tumor chemotherapy. Until now, the pathoge...
Reprogramming tumor-associated macrophages with lipid nanosystems reduces PDAC tumor burden and liver metastasis [0.03%]
使用脂质纳米系统重新编程肿瘤相关巨噬细胞可减少胰腺癌的肿瘤负荷和肝转移
Adrián Palencia-Campos,Laura Ruiz-Cañas,Marcelina Abal-Sanisidro et al.
Adrián Palencia-Campos et al.
Background: Pancreatic ductal adenocarcinoma (PDAC) requires innovative therapeutic strategies to counteract its progression and metastatic potential. Since the majority of patients are diagnosed with advanced metastatic ...
Correction: Immunotoxicity assessment of CdSe/ZnS quantum dots in macrophages, lymphocytes and BALB/c mice [0.03%]
关于CdSe/ZnS量子点的免疫毒理学评价的研究勘误：对巨噬细胞、淋巴细胞和BALB/c小鼠的影响
Xiaomei Wang,Jinglin Tian,Ken-Tye Yong et al.
Xiaomei Wang et al.
Published Erratum
Journal of nanobiotechnology. 2024 Dec 24;22(1):794. DOI:10.1186/s12951-024-02991-7 2024
A novel self-assembling peptide nanofiber hydrogel with glucagon-like peptide-1 functionality enhances islet survival to improve islet transplantation outcome in diabetes treatment [0.03%]
一种具有胰高血糖素样肽-1功能的自组装多肽纳米纤维水凝胶可提高移植胰岛细胞存活率以改善糖尿病治疗效果
Xiangheng Cai,Mengnan Zhang,Jiaqi Zou et al.
Xiangheng Cai et al.
Islet transplantation is a promising therapy for diabetes, yet the limited survival and functionality of transplanted islet grafts hinder optimal outcomes. Glucagon-like peptide-1 (GLP-1), an endogenous hormone, has shown potential to enhan...
Maiyier Muheyati,Guangheng Wu,Yilin Li et al.
Maiyier Muheyati et al.
Polymeric biomaterials have important applications in aiding clinical disease treatment, including drug delivery, bioimaging, and tissue engineering. Currently, conventional tumor chemotherapy faces obstacles such as poor solubility/stabili...
Click chemistry-based dual nanosystem for microRNA-122 detection with single-base specificity from tumour cells [0.03%]
基于点击化学的双纳米系统：从肿瘤细胞中检测具有单碱基特异性的微RNA-122
Agustín Robles-Remacho,Ismael Martos-Jamai,Mavys Tabraue-Chávez et al.
Agustín Robles-Remacho et al.
MicroRNAs (miRNAs) have been recognised as potential biomarkers due to their specific expression patterns in different biological tissues and their changes in expression under pathological conditions. MicroRNA-122 (miR-122) is a vertebrate-...