Stem cells derived exosome laden oxygen generating hydrogel composites with good electrical conductivity for the tissue-repairing process of post-myocardial infarction [0.03%]
用于心肌梗死后组织修复过程的具有良好导电性的干细胞衍生的外体负载型氧气生成水凝胶复合材料
Zhaoyan Xu,Wanzi Hong,Yuanxi Mo et al.
Zhaoyan Xu et al.
Acute myocardial infarction (AMI) destroys heart cells by disrupting the oxygen supply. Improving oxygen delivery to the injured area may avoid cell death and regenerate the heart. We present the creation of oxygen-producing injectable bio-...
Correction: An antioxidant nanozyme for targeted cardiac fbrosis therapy post myocardial infarction [0.03%]
纠正：用于心肌梗死后靶向心脏纤维化治疗的抗氧化纳米酶
Ziyi Gu,Xueliang Liu,Zhen Qi et al.
Ziyi Gu et al.
Published Erratum
Journal of nanobiotechnology. 2025 Mar 17;23(1):214. DOI:10.1186/s12951-025-03299-w 2025
Functional nanozyme system for synergistic tumor immunotherapy via cuproptosis and ferroptosis activation [0.03%]
通过激活铜死亡和铁死亡实现协同肿瘤免疫治疗的功能性纳米酶系统
Lina Gu,Ying Sun,Tingjie Bai et al.
Lina Gu et al.
Elevated copper levels induce tumor cuproptosis and ferroptosis, leading to immunogenic cell death and subsequent antitumor immune responses. However, dysregulated copper metabolism in tumor cells maintains homeostatic copper balance, while...
Retraction Note: Eobania vermiculata whole-body muscle extract-loaded chitosan nanoparticles enhanced skin regeneration and decreased pro-inflammatory cytokines in vivo [0.03%]
撤稿说明：Eobania vermiculata全身肌肉提取物负载的壳聚糖纳米粒促进皮肤再生和降低体内促炎细胞因子含量
Alyaa Farid,Adham Ooda,Ahmed Nabil et al.
Alyaa Farid et al.
Harnessing the power of traceable system C-GAP: homologous-targeting to fire up T-cell immune responses with low-dose irradiation [0.03%]
可追溯系统C-GAP的力量：利用低剂量照射的同源靶向增强T细胞免疫反应
Weijie Zhuang,Kuangwu Pan,Jie Wu et al.
Weijie Zhuang et al.
While radiotherapy-induced immunogenic cell death (ICD) holds potential for enhancing cancer immunotherapy, the conventional high-dose irradiation often leads to an immunosuppressive microenvironment and systemic toxicity. Therefore, a biom...
Injectable hydrogels with ROS-triggered drug release enable the co-delivery of antibacterial agent and anti-inflammatory nanoparticle for periodontitis treatment [0.03%]
ROS触发药物释放的可注射水凝胶能够协同运输抗生素和抗炎纳米粒子用于牙周病治疗
Yujing Zhu,Ziliang Xiu,Xiaoxi Jiang et al.
Yujing Zhu et al.
Periodontitis, a chronic inflammatory disease caused by bacteria, is characterized by localized reactive oxygen species (ROS) accumulation, leading to an inflammatory response, which in turn leads to the destruction of periodontal supportin...
Development of NIR photocleavable nanoparticles with BDNF for vestibular neuron regeneration [0.03%]
具有BDNF的近红外光可裂解纳米颗粒的开发用于前庭神经元再生
Celine Dg Abueva,Sung Ryeong Yoon,Nathaniel T Carpena et al.
Celine Dg Abueva et al.
Among nanoparticle platforms, light or photoresponsive nanoparticles have emerged as a promising drug delivery strategy with spatiotemporal control while minimizing off-target effects. The characteristic absorption spectrum of the photoresp...
Macrophage-derived mitochondria-rich extracellular vesicles aggravate bone loss in periodontitis by disrupting the mitochondrial dynamics of BMSCs [0.03%]
巨噬细胞衍生的富线粒体胞外囊泡通过破坏BMSCs的线粒体动态平衡加剧牙周炎的骨质流失
Jiayin Yan,Tian Yang,Siyuan Ma et al.
Jiayin Yan et al.
Background: Periodontitis is the leading cause of tooth loss in adults due to progressive bone destruction, which is closely related to the dysfunction of bone mesenchymal stem cells (BMSCs). Existing evidence suggests th...
Acid-responsive aggregated carrot-derived nanoantioxidants alleviate oxidative stress and restore osteoblast activity [0.03%]
响应酸性的胡萝卜衍生聚集纳米抗氧化剂，缓解氧化应激并恢复骨细胞活性
Jiao Peng,Rongyan Liu,Junyi Xu et al.
Jiao Peng et al.
Background: Excessive generation of reactive oxygen species is a hallmark of the osteoporotic bone microenvironment, which leads to the damage of mitochondrial function and the deactivation of osteoblasts. Fruits and vege...
Mesenchymal stem cell-derived extracellular vesicles alleviate autism by regulating microglial glucose metabolism reprogramming and neuroinflammation through PD-1/PD-L1 interaction [0.03%]
间充质干细胞衍生的细胞外囊泡通过PD-1/PD-L1相互作用调节小胶质细胞糖代谢重编程和神经炎症，从而缓解自闭症
Qian Qin,Linlin Fan,Xin Zeng et al.
Qian Qin et al.
Neuroinflammation triggered by microglia activation is hallmark of autism spectrum disorder (ASD), and this process includes crucial metabolic reprogramming from oxidative phosphorylation to glycolysis, which may cause neuron loss and funct...