Scalable ion concentration polarization dialyzer for peritoneal dialysate regeneration [0.03%]
可扩展的离子浓度极化透析器用于再生腹膜透析液
Wonseok Kim,Seongjun Hong,Kihong Kim et al.
Wonseok Kim et al.
A wearable artificial kidney (WAK) stands poised to offer dialysis treatment with maximal temporal and spatial flexibility for end-stage renal disease (ESRD) patients, while portability has not yet been achieved due to difficulties in porta...
Dual-pathway tumor radiosensitization strategy based on engineered bacteria capable of targeted delivery of AuNPs and specific hypoxia alleviation [0.03%]
基于工程菌实现金纳米颗粒靶向递送和特定组织缺氧缓解的肿瘤放疗增敏方法
Lingling Lei,Haonan Xu,Mingjie Li et al.
Lingling Lei et al.
Background: Radiotherapy efficacy remains constrained by two key challenges: dose-dependent toxicity to healthy tissues at high radiation doses and hypoxia-mediated tumor radioresistance. While radiosensitizers like gold ...
5-FU@HFn combined with decitabine induces pyroptosis and enhances antitumor immunotherapy for chronic myeloid leukemia [0.03%]
5-氟尿嘧啶@HFn联合地西他滨诱导焦亡并增强慢性粒细胞白血病的抗肿瘤免疫治疗
Zuowei Yuan,Guoyun Jiang,Ying Yuan et al.
Zuowei Yuan et al.
Background: Tyrosine kinase inhibitors (TKIs) constitute the primary treatment for chronic myeloid leukemia (CML). However, resistance to TKIs often leads to treatment failure. Pyroptosis, a form of programmed cell death,...
Correction: MSC microvesicles loaded G-quadruplex-enhanced circular single-stranded DNA-9 inhibits tumor growth by targeting MDSCs [0.03%]
纠正：负载G-四链体增强的环状单链DNA-9的MSC微囊泡通过作用于MDSCs发挥抑制肿瘤生长的作用
Jingxia Han,Rong Qin,Shaoting Zheng et al.
Jingxia Han et al.
Published Erratum
Journal of nanobiotechnology. 2025 Mar 26;23(1):250. DOI:10.1186/s12951-025-03313-1 2025
Radiation-induced ferroptosis via liposomal delivery of 7-Dehydrocholesterol [0.03%]
通过脂质体传递7-脱氢胆固醇辐射诱导的铁死亡
Jianwen Li,Shuyue Zhan,Wei Yang et al.
Jianwen Li et al.
Background: Ferroptosis is an emerging cell death mechanism characterized by uncontrolled lipid peroxidation. However, selectively inducing ferroptosis in cancer cells remains a challenge. ...
Extracellular vesicles: a new frontier in diagnosing and treating graft-versus-host disease after allogeneic hematopoietic cell transplantation [0.03%]
胞外囊泡：同种异体造血细胞移植后诊断和治疗移植物抗宿主病的新领域
Peipei Wu,Zhangfei Wang,Yongping Sun et al.
Peipei Wu et al.
Graft-versus-host disease (GvHD) is a prevalent complication following allogeneic hematopoietic stem cell transplantation (HSCT) and is characterized by relatively high morbidity and mortality rates. GvHD can result in extensive systemic da...
Correction: Near-infrared light triggered in situ release of CO for enhanced therapy of glioblastoma [0.03%]
修正：近红外光触发原位释放一氧化碳增强胶质母细胞瘤治疗效果
Juan Ge,Miaomiao Zuo,Qirong Wang et al.
Juan Ge et al.
Published Erratum
Journal of nanobiotechnology. 2025 Mar 25;23(1):245. DOI:10.1186/s12951-025-03162-y 2025
Biomimetic gene delivery system coupled with extracellular vesicle-encapsulated AAV for improving diabetic wound through promoting vascularization and remodeling of inflammatory microenvironment [0.03%]
仿生基因递送系统结合细胞外囊泡包裹的AAV通过促进血管化和重塑炎症微环境来改善糖尿病伤口
Shan He,Zhenhao Li,Lei Xie et al.
Shan He et al.
Adeno-associated virus (AAV)-mediated gene transfer has demonstrated potential in effectively promoting re-epithelialization and angiogenesis. AAV vector has a safety profile; however, the relatively low delivery efficacy in chronic wound w...
Dual-modality immune nano-activator harnessing Mn2⁺ and quercetin to potentiate the cGAS-STING pathway for advanced cancer metalloimmunotherapy [0.03%]
双模免疫纳米激活剂利用Mn2⁺和檞皮素增强cGAS-STING通路用于先进癌症金属免疫治疗
Shanshan Ma,Xuequan Zhang,Xiaoqi Zhu et al.
Shanshan Ma et al.
Manganese ions (Mn2+) have emerged as promising activators of the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway. However, their clinical application was hindered by low bioavailability and limited immune activa...
Reduction of colitis in mice by chemically programmed supramolecular nanoassemblies of vitamin-lipid conjugates [0.03%]
维生素-脂质偶联物的化学程序超分子纳米组件对小鼠结肠炎的改善作用
Shiyun Xian,Fanchao Meng,Xiaona Chen et al.
Shiyun Xian et al.
Inflammatory bowel disease (IBD) is a relapsing disorder characterized by uncontrolled chronic inflammation of the gastrointestinal tract, posing a significant therapeutic challenge owing to the limited efficacy and undesirable side effects...