Platycodon grandiflorum exosome-like nanoparticles: the material basis of fresh platycodon grandiflorum optimality and its mechanism in regulating acute lung injury [0.03%]
北沙参外泌体类纳米颗粒及其调节急性肺损伤机制研究
Jingmin Fu,Zhuolin Liu,Zhiying Feng et al.
Jingmin Fu et al.
Background: Acute lung injury (ALI) is a severe respiratory disease accompanied by diffuse inflammatory responses induced by various clinical causes. Many fresh medicinal plants have shown better efficacy than their dried...
Lacc1-engineered extracellular vesicles reprogram mitochondrial metabolism to alleviate inflammation and cartilage degeneration in TMJ osteoarthritis [0.03%]
工程化乳酸脱氢酶C1外泌体重编关节软骨线粒体代谢以缓解颞下颌关节炎
Xiaofeng Hu,Jian Xie,Jiansheng Su
Xiaofeng Hu
Temporomandibular joint osteoarthritis (TMJOA) is a multifaceted degenerative disease characterized by progressive cartilage degradation, chronic pain, and functional limitations of the TMJ, significantly affecting patients' quality of life...
Pharmacokinetics modulation in solid tumors through thrombin-embedded nanomedicine [0.03%]
富含凝血酶的纳米药物用于调节实体瘤中的药代动力学分布
Sheng Lin,Liuwei Zhang,Hongyan Cui et al.
Sheng Lin et al.
The development of anti-tumor nanomedicines grapples with the critical challenge of achieving sustained retention and massive intratumoral distributions of chemotherapeutics. Herein, we attempted multifaceted prodrug nanomedicine with preci...
Correction: ROS-responsive simvastatin nano-prodrug based on tertiary amine-oxide zwitterionic polymer for atherosclerotic therapy [0.03%]
基于三甲胺氧化两性离子聚合物的ROS响应型辛伐他汀纳米前药用于动脉粥样硬化治疗
Haiqin Yang,Mengcheng Guo,Qingran Guan et al.
Haiqin Yang et al.
Published Erratum
Journal of nanobiotechnology. 2025 Apr 5;23(1):277. DOI:10.1186/s12951-025-03359-1 2025
hnRNPA2B1 facilitates ovarian carcinoma metastasis by sorting cargoes into small extracellular vesicles driving myofibroblasts activation [0.03%]
hnRNPA2B1通过对货物进行分类促进卵巢癌转移从而将其驱动成肌纤维母细胞活化的小细胞外囊泡运输
Qiulei Wu,Pan Liu,Xiaoli Liu et al.
Qiulei Wu et al.
Background: Ovarian carcinoma (OvCa) metastasis is initiated and boosted by tumor-stroma interactions mediated by small extracellular vesicles (sEVs) containing microRNAs (miRNAs). However, the mechanisms of sorting relev...
Engineered endoplasmic reticulum-targeting nanodrugs with Piezo1 inhibition and promotion of cell uptake for subarachnoid hemorrhage inflammation repair [0.03%]
一种工程化内质网靶向的纳米药物用于蛛网膜下腔出血炎症修复
Xiaojian Zhang,Enyan Jiang,Wangyang Fu et al.
Xiaojian Zhang et al.
Subarachnoid hemorrhage (SAH) is a life-threatening acute hemorrhagic cerebrovascular condition, often presenting with severe headaches caused by intracranial hypertension, which in severe cases can lead to brain herniation. Piezo1 is a mec...
Closed-loop cascade nanozyme strategy for mutually reinforced catalytic and mild-temperature photothermal therapeutic effects [0.03%]
闭环级联纳米酶策略实现催化和中温光热治疗的协同效应
Fan Yang,Chunyu Yan,Nannan Li et al.
Fan Yang et al.
Nanocatalysis coupled with photothermal therapy is a potent anti-cancer approach, yet its clinical utility is limited by low concentration of tumor substrate, redox interference, and risks of overheating normal tissues. Herein, we propose a...
Correction: Chitosan oligosaccharide decorated liposomes combined with TH302 for photodynamic therapy in triple negative breast cancer [0.03%]
纠正：壳聚糖寡糖修饰的脂质体与TH302联合用于三阴性乳腺癌光动力治疗
Yinan Ding,Rui Yang,Weiping Yu et al.
Yinan Ding et al.
Published Erratum
Journal of nanobiotechnology. 2025 Apr 5;23(1):275. DOI:10.1186/s12951-025-03268-3 2025
Exosome-like vesicles encapsulated with specific microRNAs accelerate burn wound healing and ameliorate scarring [0.03%]
包裹特定microRNA的类外泌体囊泡加速烧伤伤口愈合并减轻疤痕形成
Zhiyong Lei,Xiaojuan Chen,Kezhuo Chen et al.
Zhiyong Lei et al.
Burn injuries are prevalent, yet effective treatments remain elusive. Exosomes derived from mesenchymal stem cells (MSC-Ex) possess remarkable pro-regenerative properties for wound healing. Despite their potential, the challenge of mass pro...
A smartphone-colorimetric dual-mode diagnosis method for breast cancer detection of BRCA-1 gene base on silver plated substrate and catalytic hairpin assembly amplification [0.03%]
基于银镀底物和催化发夹组装扩增的BRCA-1基因智能手机比色双模诊断法检测乳腺癌
Zan Yu,Wenxin Liu,Lei Wang
Zan Yu
Breast cancer is the most prevalent malignancy among women worldwide. With rapid societal development, there has been a consistent increase in breast cancer incidence rates annually, accompanied by a progressively younger age of onset. Cons...