Correction: Neutrophil-macrophage hybrid membrane-coated prussian blue nanozyme for ulcerative colitis treatment and mechanistic insights [0.03%]
校正：中性粒细胞-巨噬细胞杂合膜包裹的普鲁士蓝纳米酶在溃疡性结肠炎治疗中的应用及机制探索
Chunli Hu,Yanhui Wang,Shengtao Liao et al.
Chunli Hu et al.
Published Erratum
Journal of nanobiotechnology. 2025 Feb 20;23(1):125. DOI:10.1186/s12951-025-03207-2 2025
New horizons for the therapeutic application of nanozymes in cancer treatment [0.03%]
纳米酶在癌症治疗中治疗应用的新视野
Pravanjan Malla,Yu-Ming Wang,Chia-Hao Su
Pravanjan Malla
The advent of nanozymes has revolutionized approaches to cancer diagnosis and therapy, introducing innovative strategies that address the limitations of conventional treatments. Nanozyme nanostructures with enzyme-mimicking catalytic abilit...
Extracellular vesicle-mediated gene therapy targets BRAFV600E-mutant colorectal cancer by inhibiting the MEK1/2-ERK1/2 pathway [0.03%]
通过抑制MEK1/2-ERK1/2通路，胞外囊泡介导的基因治疗靶向BRAFV600E突变结肠癌
Di Wang,Liwei Wang,Wei Zhang et al.
Di Wang et al.
Background: Patients with colorectal cancer (CRC) harboring BRAF mutation have a poor prognosis. The median survival time for patients with advanced BRAFV600E-mutant CRC is only approximately one year. Owing to the insens...
Bio-nanocomplexes impair iron homeostasis to induce non-canonical ferroptosis in cancer cells [0.03%]
生物纳米复合物干扰铁稳态诱导癌细胞发生非典型性铁死亡
Xin Wang,Tianyi Zhang,Shuai Wang et al.
Xin Wang et al.
The targeted elevation of the labile iron pool (LIP) represents the most direct and effective strategy to induce ferroptosis in cancer cells. However, the efficiency of increasing LIP to induce ferroptosis via iron supplementation is contro...
A wearable enzyme sensor enabled by the floating-gate OECT with poly(benzimidazobenzophenanthroline) as the catalytic layer [0.03%]
采用聚(苯并咪唑苯并菲仁)作为催化层的浮栅OECT使能的可穿戴酶传感器
Jianlong Ji,Jing Xiao,Fan Zhang et al.
Jianlong Ji et al.
With the advantages of miniaturization, simple device structure, and fast response, the organic electrochemical transistor (OECT) has become an emerging platform for developing wearable enzyme sensors for real-time health monitoring. The fl...
Remodeling tumor microenvironment using prodrug nMOFs for synergistic cancer therapy [0.03%]
使用前药纳米多孔金属有机框架重构肿瘤微环境以实现协同癌症治疗
Junliang Dong,Jindong Ding,Shifan Luo et al.
Junliang Dong et al.
Metal-organic frameworks (MOFs) hold tremendous potential in cancer therapy due to their remarkable structural and functional adaptability, enabling them to serve as nanocarriers for biopharmaceuticals and nanoreactors for organizing cascad...
Tungsten-based polyoxometalate nanoclusters as ferroptosis inhibitors modulating S100A8/A9-mediated iron metabolism pathway for managing intracerebral haemorrhage [0.03%]
基于钨的聚氧金属簇作为通过调节S100A8/A9介导的铁代谢通路来管理脑出血的铁死亡抑制剂
Yang Yang,Mingzhu Lv,Ruihong Liu et al.
Yang Yang et al.
Background: Intracerebral haemorrhage (ICH) is a devastating neurological disorder with high morbidity and mortality rates, largely owing to the lack of effective therapeutic strategies. Growing evidence has underscored t...
Enzymatically responsive nanocarriers targeting PD-1 and TGF-β pathways reverse immunotherapeutic resistance and elicit robust therapeutic efficacy [0.03%]
酶响应型纳米载体靶向PD-1和TGF-β信号通路逆转免疫治疗抵抗并产生强大的疗效
Ying-Tzu Yen,Zhifan Zhang,Anni Chen et al.
Ying-Tzu Yen et al.
Immune checkpoint inhibitors (ICIs) have revolutionized lung cancer treatment, yet resistance remains a challenge. Co-inhibition of PD-1/PD-L1 and TGF-β shows promise but faces limited efficacy and systemic toxicity. We developed gelatinas...
Modulating metal-organic frameworks by surface engineering of stearic acid modification for follicular drug delivery and enhanced hair growth promotion [0.03%]
通过硬脂酸修饰的表面工程调制金属有机框架用于毛囊药物传递和促进头发生长
Zehui He,Zhenda Liu,Yongtai Zhang et al.
Zehui He et al.
Cyclodextrin metal-organic frameworks (CD-MOF) as delivery carriers have gained great attention in the biomedical field. However, limited by challenges of moisture-sensitive nature, the design and application of CD-MOF-based hair follicle d...
Epitope-focused vaccine immunogens design using tailored horseshoe-shaped scaffold [0.03%]
使用定制的蹄铁形支架设计以表位为重点的疫苗免疫原
Fangxin Zhao,Yue Zhang,Zhiling Zhang et al.
Fangxin Zhao et al.
The continuous emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants highlights the need to update coronavirus 2019 disease (COVID-19) vaccine components. Epitope-based vaccine designs targeting conserved and im...