Graphdiyne biomaterials: from characterization to properties and applications [0.03%]
石图炔生物材料：从特征分析到性质和应用
Ling-Xiao Zhao,Yong-Gang Fan,Xue Zhang et al.
Ling-Xiao Zhao et al.
Graphdiyne (GDY), the sole synthetic carbon allotrope with sp-hybridized carbon atoms, has been extensively researched that benefit from its pore structure, fully conjugated surfaces, wide band gaps, and more reactive C≡C bonds. In additio...
Spermine delivered by ZIF90 nanoparticles alleviates atherosclerosis by targeted inhibition of macrophage ferroptosis in plaque [0.03%]
通过ZIF90纳米颗粒靶向抑制斑块内巨噬细胞铁死亡来缓解动脉粥样硬化中的左旋孢胺
Yuwu Chen,Biyi Xu,Quan Lin et al.
Yuwu Chen et al.
Background: Nowadays, emerging evidence have suggested that the ferroptosis of macrophages could contribute to the progression of atherosclerosis (AS). Meanwhile, Spermine (Sp) could serve as an endogenous small molecule ...
Cascade-recharged macrophage-biomimetic ruthenium-based nanobattery for enhanced photodynamic-induced immunotherapy [0.03%]
级联式宏噬细胞仿生钌基纳米电池用于增强光动力免疫治疗
Guoyu Xia,Zhongxiong Fan,Qingluo Wang et al.
Guoyu Xia et al.
Photodynamic-induced immunotherapy (PDI) is often hampered by low reactive oxygen species (ROS) yield, intra-tumor hypoxia, high glutathione (GSH) concentration, and immunosuppressive microenvironment. In view of this, a ruthenium (Ru)-base...
Infertility treatment using polysaccharides-based hydrogels: new strategies in tissue engineering and regenerative medicine [0.03%]
使用多糖水凝胶进行不孕症治疗：组织工程和再生医学的新策略
Maryam Ghahremani-Nasab,Soraya Babaie,Sara Bazdar et al.
Maryam Ghahremani-Nasab et al.
Infertility is a primary health issue affecting about 15% of couples of reproductive ages worldwide, leading to physical, mental, and social challenges. Advances in nanobiotechnology and regenerative medicine are opening new therapeutic hor...
Specific muscle targeted delivery of miR-130a loaded lipid nanoparticles: a novel approach to inhibit lipid accumulation in skeletal muscle and obesity [0.03%]
负载miR-130a的脂质纳米颗粒靶向特定肌肉传递：一种新颖的抑制骨骼肌中脂质积累和肥胖的方法
Yingqian Wang,Zeqiang Ma,Lehua Jiang et al.
Yingqian Wang et al.
Background: Skeletal muscle lipid deposition is a key manifestation of obesity, often accompanied by decreased exercise capacity and muscle atrophy. Skeletal muscle as the largest organ in the body, makes it challenges fo...
Multidimensional applications of prussian blue-based nanoparticles in cancer immunotherapy [0.03%]
普鲁士蓝基纳米颗粒在癌症免疫治疗中的多维应用
Jiayi Zhang,Fang Wang,Zhaogang Sun et al.
Jiayi Zhang et al.
Immunotherapy holds notable progress in the treatment of cancer. However, the clinical therapeutic effect remains a significant challenge due to immune-related side effects, poor immunogenicity, and immunosuppressive microenvironment. Nanop...
Conditioning period impacts the morphology and proliferative effect of extracellular vesicles derived from rat adipose tissue derived stromal cell [0.03%]
条件培养期对大鼠脂肪间充质干细胞来源的细胞外囊泡形态及增殖效果的影响
Borger Anton,Haertinger Maximilian,Millesi Flavia et al.
Borger Anton et al.
A serum-free conditioning period is a crucial step during small extracellular vesicle (sEV) preparation ranging from 12 to 72h. There is a paucity of knowledge about downstream effects of serum-free conditioning on sEVs and the optimal dura...
3D printed porous magnesium metal scaffolds with bioactive coating for bone defect repair: enhancing angiogenesis and osteogenesis [0.03%]
具有生物活性涂层的3D打印多孔镁金属支架用于骨缺损修复：促进血管生成和成骨作用
Jianting Ye,Bozun Miao,Yingjie Xiong et al.
Jianting Ye et al.
In orthopedics, the effective treatment of bone defects remains a major challenge. Magnesium (Mg) metals, with their excellent biocompatibility and favorable osteoconductivity, osteoinductivity, and osseointegration properties, hold great p...
Exploring the link between M1 macrophages and EMT of amniotic epithelial cells: implications for premature rupture of membranes [0.03%]
M1型巨噬细胞和羊膜上皮细胞的EMT之间的联系的研究：对胎膜早破的意义
Yuhua Gao,Yanan Zhang,Ningning Mi et al.
Yuhua Gao et al.
Background: Despite increasing evidence supporting the role of an amniotic epithelial-mesenchymal transition (EMT) in the premature rupture of membranes (PROMs), it remains unclear if extracellular vesicle (EV) derived fr...
Nanomedicine's shining armor: understanding and leveraging the metal-phenolic networks [0.03%]
纳米医学的坚固护甲：了解和利用金属酚网络
Zhengming Tang,Zhijie Huang,Yisheng Huang et al.
Zhengming Tang et al.
Metal-phenolic networks (MPNs), which comprise supramolecular amorphous networks formed by interlinking polyphenols with metal ions, garner escalating interest within the realm of nanomedicine. Presently, a comprehensive synthesis of the cu...