3D cell-laden scaffold printed with brain acellular matrix bioink [0.03%]
一种含有脑无细胞基质生物墨水的负载细胞支架的3D打印技术
Aobo Zhang,Siyu Zhu,Boyu Sun et al.
Aobo Zhang et al.
Gut microbiota contributes to polystyrene nanoplastics-induced fetal growth restriction by disturbing placental nicotinamide metabolism [0.03%]
肠道微生物群通过干扰胎盘烟酸代谢参与聚苯乙烯纳米塑料诱导的胎儿生长受限
Yijing He,Qiao Li,Qinfeng Sun et al.
Yijing He et al.
Polystyrene nanoplastics (PS-NPs) are ubiquitous in the environment, eliciting significant concerns about their possible risks to human health, especially reproductive health. Various reproductive toxicities of PS-NPs have been reported, ho...
Exploring the bioactivity of MicroRNAs Originated from Plant-derived Exosome-like Nanoparticles (PELNs): current perspectives [0.03%]
植物衍生类似外泌体纳米颗粒中微小RNA生物活性的研究进展及展望
Kingsley Miyanda Tembo,Xiaohui Wang,Mansoor Bolideei et al.
Kingsley Miyanda Tembo et al.
Exosomes, nano-sized extracellular vesicles, facilitate intercellular communication by transferring biomolecules such as microRNAs (miRNAs), which are key regulators of gene expression. While mammalian-derived exosomes (MDEs) have shown the...
Tumor-microenvironment triggered Mn-Gd based nanosystem for breast carcinoma suppression via synergistic radiotherapy and glutathione-depleting along with glucose oxidase combination enhanced Ros storm [0.03%]
肿瘤微环境触发的Mn-Gd基纳米系统通过协同放疗和谷胱甘肽耗尽以及葡萄糖氧化酶组合增强ROS风暴来抑制乳腺癌的发展
Yonghui Su,Dongqun Guo,Yinghao Liang et al.
Yonghui Su et al.
Background: Cancer treatment commonly involves radiation as a primary therapy, affecting nearly two-thirds of patients. The use of combination therapies is gaining traction, with the aim of achieving synergistic effects t...
Dynamic three-dimensional culture enhances tunneling nanotubes-mediated mitochondrial transfer in mesenchymal stromal cells to accelerate wound healing [0.03%]
动态三维培养促进间充质基质细胞中穿膜纳米管介导的线粒体转移以加速伤口愈合
Lin Ma,Xiaoxue Yang,Xiaoyao Huang et al.
Lin Ma et al.
Mesenchymal stromal cells (MSCs) have shown promise in treating various diseases, and optimizing their therapeutic potential is a crucial objective in MSCs-based clinical applications. The microenvironment, particularly three-dimensional (3...
Spikey biodegradable MXene nanosheets with enhanced cellular internalization and stimuli-responsive drug delivery for synergistic cancer therapy [0.03%]
具有增强的细胞内吞作用和刺激响应药物递送的spikey可生物降解MXene纳米片用于协同癌症治疗
Tiankun Hui,Chen Wang,Chenchen Fu et al.
Tiankun Hui et al.
Exo-hydrogel therapy: a revolutionary approach to managing diabetic complications [0.03%]
外凝胶疗法：一种治疗糖尿病并发症的革命性方法
Yiming Meng,Jing Sun,Yushu Ma et al.
Yiming Meng et al.
This review systematically examines the transformative potential of Exosome-hydrogel (Exo-gel) composite systems in combating diabetic complications, with a particular emphasis on their macromolecular interactions and therapeutic implicatio...
Pre-formation loading of extracellular vesicles with exogenous molecules using photoporation [0.03%]
基于光穿孔技术的外源物质装载到细胞外囊泡中研究
Jana Ramon,Cláudio Pinheiro,Charysse Vandendriessche et al.
Jana Ramon et al.
Despite the natural capacity of extracellular vesicles (EVs) to encapsulate intracellular compounds and transfer these to nearby or distant recipient cells, the intentional loading of EVs with cargo molecules remains a challenging endeavor....
Novel multifunctional targeted nanozyme as an ultrasound contrast agent for real-time monitoring and treatment of congenital hydronephrosis renal fibrosis [0.03%]
用于监测和治疗先天性肾积水肾纤维化的新型多功能靶向纳米酶超声造影剂
Qian Zhao,Di Zhang,Keyan Chen et al.
Qian Zhao et al.
Background: Congenital Hydronephrosis (CH) is a common pediatric disorder that often leads to renal fibrosis (RF), significantly impairing kidney function. Oxidative stress (OS) plays a central role in the pathogenesis of...
N6-methyladenosine-modified circDCP2 promotes carbon black nanoparticle-induced malignancy in human bronchial epithelial cells via PI3K-AKT pathway and macrophage homeostasis [0.03%]
N6-甲基腺苷修饰的circDCP2通过PI3K-AKT通路和巨噬细胞稳态促进碳黑纳米颗粒诱导的人支气管上皮细胞恶性肿瘤发生发展
Shulin Qin,Kexin Chen,Shanfeng Chen et al.
Shulin Qin et al.
Long-term exposure to environmental carbon black nanoparticles (CBNP) has been shown to increase the risk of pulmonary malignancies. However, the role of epigenetic regulation, particularly circular RNAs (circRNAs), in this process remains ...