Engineered endoplasmic reticulum-targeting nanodrugs with Piezo1 inhibition and promotion of cell uptake for subarachnoid hemorrhage inflammation repair [0.03%]
一种工程化内质网靶向的纳米药物用于蛛网膜下腔出血炎症修复
Xiaojian Zhang,Enyan Jiang,Wangyang Fu et al.
Xiaojian Zhang et al.
Subarachnoid hemorrhage (SAH) is a life-threatening acute hemorrhagic cerebrovascular condition, often presenting with severe headaches caused by intracranial hypertension, which in severe cases can lead to brain herniation. Piezo1 is a mec...
Closed-loop cascade nanozyme strategy for mutually reinforced catalytic and mild-temperature photothermal therapeutic effects [0.03%]
闭环级联纳米酶策略实现催化和中温光热治疗的协同效应
Fan Yang,Chunyu Yan,Nannan Li et al.
Fan Yang et al.
Nanocatalysis coupled with photothermal therapy is a potent anti-cancer approach, yet its clinical utility is limited by low concentration of tumor substrate, redox interference, and risks of overheating normal tissues. Herein, we propose a...
Correction: Chitosan oligosaccharide decorated liposomes combined with TH302 for photodynamic therapy in triple negative breast cancer [0.03%]
纠正：壳聚糖寡糖修饰的脂质体与TH302联合用于三阴性乳腺癌光动力治疗
Yinan Ding,Rui Yang,Weiping Yu et al.
Yinan Ding et al.
Published Erratum
Journal of nanobiotechnology. 2025 Apr 5;23(1):275. DOI:10.1186/s12951-025-03268-3 2025
Exosome-like vesicles encapsulated with specific microRNAs accelerate burn wound healing and ameliorate scarring [0.03%]
包裹特定microRNA的类外泌体囊泡加速烧伤伤口愈合并减轻疤痕形成
Zhiyong Lei,Xiaojuan Chen,Kezhuo Chen et al.
Zhiyong Lei et al.
Burn injuries are prevalent, yet effective treatments remain elusive. Exosomes derived from mesenchymal stem cells (MSC-Ex) possess remarkable pro-regenerative properties for wound healing. Despite their potential, the challenge of mass pro...
A smartphone-colorimetric dual-mode diagnosis method for breast cancer detection of BRCA-1 gene base on silver plated substrate and catalytic hairpin assembly amplification [0.03%]
基于银镀底物和催化发夹组装扩增的BRCA-1基因智能手机比色双模诊断法检测乳腺癌
Zan Yu,Wenxin Liu,Lei Wang
Zan Yu
Breast cancer is the most prevalent malignancy among women worldwide. With rapid societal development, there has been a consistent increase in breast cancer incidence rates annually, accompanied by a progressively younger age of onset. Cons...
Correction: Conditioning period impacts the morphology and proliferative effect of extracellular vesicles derived from rat adipose tissue derived stromal cell [0.03%]
订正：培养时间影响大鼠脂肪组织间充质干细胞来源细胞外囊泡的形态及其增殖作用
Anton Borger,Maximilian Haertinger,Flavia Millesi et al.
Anton Borger et al.
Published Erratum
Journal of nanobiotechnology. 2025 Apr 2;23(1):265. DOI:10.1186/s12951-025-03345-7 2025
Extracellular particles: emerging insights into central nervous system diseases [0.03%]
细胞外颗粒：中枢神经系统疾病的新兴研究观点
Shenyuan Chen,Qinghua Bao,Wenrong Xu et al.
Shenyuan Chen et al.
Extracellular particles (EPs), including extracellular vesicles (EVs) and non-vesicular extracellular particles (NVEPs), are multimolecular biomaterials released by cells that play a crucial role in intercellular communication. Recently, ne...
Therapeutic potential of apoptotic vesicles in modulating inflammation, immune responses, and tissue regeneration [0.03%]
凋亡小体在调控炎症、免疫反应和组织再生中的治疗潜力
Mohammad Amin Khalilzad,Javad Mohammadi,Soumayeh Amirsaadat et al.
Mohammad Amin Khalilzad et al.
The process of apoptosis plays a crucial role in tissue homeostasis, immune system regulation, and organ formation. Apoptotic vesicles (ApoEVs) are involved in efferocytosis, the process by which phagocytes ingest dead cells. ApoEVs also ha...
Oral administration of Momordica charantia-derived extracellular vesicles alleviates ulcerative colitis through comprehensive renovation of the intestinal microenvironment [0.03%]
口服苦瓜来源的细胞外囊泡通过全面改造肠道微环境来缓解溃疡性结肠炎
Bowen Gao,Xiaoling Huang,Junlong Fu et al.
Bowen Gao et al.
Background: Ulcerative colitis (UC) is an inflammatory bowel disease (IBD), accompanied by intense inflammation, oxidative stress, and intestinal microbiota dysbiosis. Current treatments using chemotherapeutic drugs or im...
Exogenous nano-silicon enhances the ability of intercropped faba bean to alleviate cadmium toxicity and resist Fusarium wilt [0.03%]
外源纳米硅增强了蚕豆间作缓解镉毒性及抵抗萎蔫病的能力
Chaosheng Luo,Ting Li,You Huang et al.
Chaosheng Luo et al.
Excessive soil cadmium (Cd) and the accumulation of pathogens pose serious threats to legume growth. However, it remains unclear whether intercropping (IFcd) and its combined treatment with silicon nanoparticles (Si-NPs) (IFcd + Si) can all...