Engineered MSC-EVs loaded with BDNF-enhancing neuropeptides via a non-disruptive method enhance post-stroke neuroregeneration via intranasal delivery [0.03%]
通过非破坏性方法加载脑源性神经营养因子增强神经肽的工程化间充质干细胞外泌体经鼻递送促进卒中后神经再生
Ji-Eun Kim,Ye Eun Ji,Hyeon Jun Hwang et al.
Ji-Eun Kim et al.
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) show potential as neuroregenerative therapies. Incorporating bioactive compounds such as neuropeptides that enhance brain-derived neurotrophic factor (BDNF) expression may ampli...
Correction: N-doped carbon dots for dual-modality NIR fluorescence imaging and photothermal therapy [0.03%]
N-掺杂碳点用于双模近红外荧光成像和光热治疗的订正公告
Hui-Xian Shi,Xuan Qu,Tong-Tong Zhao et al.
Hui-Xian Shi et al.
Published Erratum
Journal of nanobiotechnology. 2025 Aug 29;23(1):591. DOI:10.1186/s12951-025-03662-x 2025
The bone marrow mesenchymal stem cells derived migrasomes induced by Titania nanotubes surface serve as chemotaxis effect for osteogenesis [0.03%]
由二氧化钛纳米管表面诱导的骨髓间充质干细胞源迁移体作为成骨趋化效应
Guangwen Li,Yan Zhang,Haochen Wang et al.
Guangwen Li et al.
The regulatory role of migrasomes (Migs) has attracted growing attentions recently. However, most of the reports only focus on the influence of donor cells on Migs contents, regarding the substrate information. In the present study, the bon...
Genetically engineered Magnesium/Manganese nanoparticles for cancer radioimmunotherapy [0.03%]
基因工程镁/锰纳米颗粒用于癌症放射免疫治疗
Jicheng Wu,Yangtao Xu,Yunjing Zhang et al.
Jicheng Wu et al.
Radiotherapy (RT) has great potential on activating antitumor immunity for combination therapy, yet this effect is limited by immunosuppressive tumor microenvironment (TME) and the potential toxicity in immune cells from high-dose radiation...
Sparking angiogenesis by carbon monoxide-rich gold nanoparticles obtained by pulsed laser driven CO2 reduction reaction [0.03%]
一氧化碳富集的金纳米颗粒促进血管生成：飞秒激光脉冲引发二氧化碳还原反应制备该纳米粒子研究
Anastasia Chillà,Cecilia Anceschi,Francesca Scavone et al.
Anastasia Chillà et al.
Endothelial tissue regeneration is a major challenge in the context of vascular disorders and tissue repair. One of the most recent and promising therapies for endothelial tissue disorders is the administration of carbon monoxide (CO) by di...
Lithium-doped calcium silicate scaffolds-activated M2-polarized macrophage-derived miR-145-5p-riched extracellular vesicles to enhance osteoimmunomodulation for accelerating bone regeneration [0.03%]
锂掺杂的钙硅酸盐支架活化M2极化巨噬细胞来源的富含miR-145-5p的外泌体促进成骨免疫调节和骨再生
Ting-You Kuo,Tsung-Li Lin,Yen-Hong Lin et al.
Ting-You Kuo et al.
Bone healing is intricately associated with dynamic macrophage polarization. Modulating macrophages toward the M2 phenotype has emerged as a promising strategy in bone tissue engineering. Calcium silicate, known for its superior osteoconduc...
Injured renal cell membrane encapsulated ICG/CORM-401 for homologous targeted NIR theranostics of acute kidney injury [0.03%]
负载ICG/CORM-401的损伤肾细胞膜类囊体同源靶向诊断联合近红外光治疗急性肾损伤
Shijie Yao,Yinan Wang,Liqiang Shao et al.
Shijie Yao et al.
Acute kidney injury (AKI) is frequently attributed to the lack of effective early diagnosis and incorrect timing for treatment, resulting in a high incidence rate and mortality. Currently, there is no precise clinical treatment available fo...
Drug repurposing: isosorbide mononitrate enhances tumor accumulation to augment sonodynamic therapy for hepatocellular carcinoma [0.03%]
药物再利用：单硝酸异山梨酯增强肿瘤聚集以增强声动力疗法用于肝细胞癌治疗
Yu Peng,Zhe Li,Lei Zhou et al.
Yu Peng et al.
Hepatocellular carcinoma (HCC) remains a leading cause of cancer death worldwide. Sonodynamic therapy (SDT) offers a non-invasive, deep-penetrating approach by using ultrasound to activate sonosensitizers and generate cytotoxic reactive oxy...
Ultrasound-actuated platelet mimetic nanomotors enable targeted piezocatalytic ROS storm for precision thrombolysis [0.03%]
超声波驱动的血小板仿生纳米马达实现精准溶栓用定位型压电催化ROS风暴疗法
Ye Zhao,Jinchen He,Yuxi Liu et al.
Ye Zhao et al.
Thrombotic diseases pose life-threatening risks, yet current thrombolytic therapies face limitations including poor targeting and bleeding risks. To address this, ultrasound-activatable nanomotors (hBT-Pt@Pm) were developed through the inte...
Targeted neural stem cell-derived extracellular vesicles loaded with Sinomenine alleviate diabetic peripheral neuropathy via WNT5a/TRPV1 pathway modulation [0.03%]
延胡索酸恩夫韦肽负载靶向神经干细胞源性外泌体通过调节WNT5a/TRPV1信号通路改善糖尿病周围神经病变
Ji Chen,Lin Zhu,Yangyuxi Chen et al.
Ji Chen et al.
Background: Diabetic peripheral neuropathy (DPN) is one of the most prevalent and debilitating complications of diabetes, marked by chronic neuroinflammation, immune dysregulation, and progressive neuronal degeneration. C...