Liangxing Tu,Zijian Zou,Ye Yang et al.
Liangxing Tu et al.
Atherosclerosis is a complex cardiovascular disease driven by multiple factors, including aging, inflammation, oxidative stress, and plaque rupture. The progression of this disease is often covert, emphasizing the need for early biomarkers ...
Oxidative stress induced paclitaxel-derived carbon dots inhibit glioblastoma proliferation and EMT process [0.03%]
氧化应激诱导的紫杉醇衍生碳点抑制胶质母细胞瘤增殖和上皮间充质转化过程
Haiyang Yan,Huimin Miao,Jiukun Hu et al.
Haiyang Yan et al.
Glioblastoma represents the most prevalent and deadly form of brain tumor with limited therapeutic drugs. The existence of the blood-brain barrier (BBB) hinders drugs permeate to the brain efficiently. Nowadays, nano-formulations, particula...
The nucleic acid reactions on the nanomaterials surface for biomedicine [0.03%]
纳米材料表面核酸反应的生物医学效应研究进展
Zhenrui Xue,Lu Wang,Shengnan Pan et al.
Zhenrui Xue et al.
Integrating nucleic acids (NAs) with nanomaterials has substantially advanced biomedical research, enabling critical applications in biosensing, drug delivery, therapeutics, and the synthesis of nanomaterials. At the core of these advances ...
PTEN as a prognostic factor for radiotherapy plus immunotherapy response in nasopharyngeal carcinoma [0.03%]
PTEN作为放射治疗联合免疫治疗对鼻咽癌疗效的预后因素
Jiaxing Guo,Ming Zhang,Xiaoli Li et al.
Jiaxing Guo et al.
Background: In the context of nasopharyngeal carcinoma (NPC) treatment, radiotherapy combined with immunotherapy (IR + RT) is gaining traction. This study focuses on analyzing exosomal proteins, particularly Phosphatase a...
Current progress and remaining challenges of peptide-drug conjugates (PDCs): next generation of antibody-drug conjugates (ADCs)? [0.03%]
肽药物偶联物(PDCs)的最新研究进展及其面临的挑战——抗体药物偶联物(ADCs)的下一代产品?
Dongyuan Wang,Feng Yin,Zigang Li et al.
Dongyuan Wang et al.
Drug conjugates have emerged as a promising alternative delivery system designed to deliver an ultra-toxic payload directly to the target cancer cells, maximizing therapeutic efficacy while minimizing toxicity. Among these, antibody-drug co...
Nanoplastics-mediated physiologic and genomic responses in pathogenic Escherichia coli O157:H7 [0.03%]
纳米塑料对致病性大肠杆菌O157:H7生理学和基因组的响应
Jayashree Nath,Goutam Banerjee,Jayita De et al.
Jayashree Nath et al.
The widespread occurrence of microplastics (MP) and nanoplastics (NP) in the environment is commonly thought to negatively impact living organisms; however, there remains a considerable lack of understanding regarding the actual risks assoc...
Migrasomes as intercellular messengers: potential in the pathological mechanism, diagnosis and treatment of clinical diseases [0.03%]
迁移体作为细胞间信息传递的介质：潜在病理机制、诊断和治疗作用及其临床应用展望
Qingfu Zhang,Jianyao Su,Zhichao Li et al.
Qingfu Zhang et al.
Migrasomes are newly identified organelles that were first discovered in 2015. Since then, their biological structure, formation process, and physiological functions have been gradually elucidated. Research in recent years has expanded our ...
Celery seed derived reconstituted lipid nanoparticles as an innate neuron-targeted neuroprotective nanomedicine for ischemic stroke treatment [0.03%]
来源于芹菜籽的天然神经靶向神经保护纳米药物用于缺血性脑卒中治疗
Dan Han,Jiaxing Zhang,Dingran Li et al.
Dan Han et al.
Background: Ischemic stroke (IS) is the leading cause of worldwide death while the discovery and effective delivery of neuroprotective agents for satisfied IS treatment is still challenging. ...
Biomaterial-based drug delivery systems in the treatment of inner ear disorders [0.03%]
基于生物材料的药物递送系统在内耳疾病治疗中的应用
Hong Cheng,Bin Zhang,Pei Jiang et al.
Hong Cheng et al.
Inner ear disorders are among the predominant etiology of hearing loss. The blood-labyrinth barrier limits the ability of drugs to attain pharmacologically effective concentrations within the inner ear; consequently, delivering drugs system...
NIR-programmable 3D-printed shape-memory scaffold with dual-thermal responsiveness for precision bone regeneration and bone tumor management [0.03%]
近红外光编程的双热响应性3D打印形状记忆支架用于精准骨再生和骨肿瘤治疗
Hui Wang,Jiaxin Zhang,Zuhao Li et al.
Hui Wang et al.
Clinically, intraoperative treatment of bone tumors presents several challenges, including the effective inactivation of tumors and filling of irregular bone defects after tumor removal. In this study, intelligent thermosensitive composite ...