Correction: Single‑cell multi‑omics analysis reveals the mechanism of action of a novel antioxidant polyphenol nanoparticle loaded with STAT3 agonist in mediating cardiomyocyte ferroptosis to ameliorate age‑related heart failure [0.03%]
纠正:单细胞多组学分析揭示了一种新型抗氧化多酚纳米颗粒装载STAT3激动剂介导心肌细胞铁死亡改善年龄相关性心力衰竭的作用机制
Haoyuan Zheng,Yuan Tian,Dongyu Li et al.
Haoyuan Zheng et al.
Published Erratum
Journal of nanobiotechnology. 2025 Oct 14;23(1):674. DOI:10.1186/s12951-025-03739-7 2025
Programmable metal-based immuno-photocatalytic nanoparticles for precision activation of anti-tumor immunity [0.03%]
可编程金属免疫光催化纳米粒子精准激活抗肿瘤免疫响应
Tianbo Liu,Ling Yang,Yucheng Hou et al.
Tianbo Liu et al.
In spite of the introduction of cancer immunotherapy for improving tumor suppression, the modality of this revolutionary treatment has faced a number of challenges because of immune evasion, poor tumor immunogenicity, and resistance in soli...
Nanobody Immunolabelling and three-dimensional imaging reveals spatially restricted LYVE1 expression by kidney lymphatic vessels in mice [0.03%]
纳米抗体免疫标记和三维成像显示小鼠肾脏淋巴管的空间限制性LYVE1表达
Eva Maria Funk,Daniyal J Jafree,Nils Rouven Hansmeier et al.
Eva Maria Funk et al.
Background: Lymphatic vessels are complex three-dimensional (3D) structures that facilitate tissue fluid clearance and regulate immune responses during health and inflammation. Recent advances in wholemount immunolabellin...
Extracellular vesicles in metabolic perspective: mechanism and targeted therapy [0.03%]
代谢视角下的细胞外囊泡:机制与靶向治疗
Qifeng Sheng,Zebin Wu,Wenming Li et al.
Qifeng Sheng et al.
Intercellular metabolic communication is essential for maintaining homeostasis and normal physiological function. Extracellular vesicles (EVs), as key mediators of cell-to-cell communication, are increasingly recognized for their close asso...
Programmable macrophage-polarizing nanoparticles for MRI-guided early detection and treatment of pulmonary metastases [0.03%]
用于磁共振引导的肺转移早期检测和治疗的可编程巨噬细胞极化纳米粒子
Meiju Sui,Kairu Xie,Yingying Luo et al.
Meiju Sui et al.
Metastatic lung cancer remains a leading cause of cancer-related mortality worldwide, underscoring the urgent need for early detection and intervention strategies. Current diagnostic and therapeutic methods often fall short in sensitivity a...
Lipid metabolism and lipid signaling in extracellular vesicles ontogeny: from biogenesis to functional execution [0.03%]
细胞外囊泡发生过程中的脂代谢与脂信号转导:从生物发生成到功能执行
Jiaxin Zhang,Jiali Li,Yuzhou Zheng et al.
Jiaxin Zhang et al.
This review explores the bidirectional relationship between lipids and extracellular vesicles (EVs) throughout the EV lifecycle. Lipid metabolism and lipid signaling influence EV biogenesis, cargo sorting, release, and targeting. EVs are ke...
Biomimetic ferritin nanocages for synergistic co-delivery of metformin and rapamycin restore neurodevelopmental homeostasis in autism spectrum disorders [0.03%]
类铁蛋白仿生纳米笼协同递送二甲双胍和雷帕霉素恢复自闭症谱系障碍的神经发育平衡
Yizhe Shen,Lele Yu,Liujiao Wang et al.
Yizhe Shen et al.
Autism spectrum disorder (ASD) is a multifactorial neurodevelopmental disorder with limited treatment options, largely due to its complex etiology and the inadequate delivery of therapeutics to the central nervous system. Herein, we report ...
Orally administered degradable nanoarmor-assisted probiotics for remodeling the gut microenvironment and treating osteoporosis [0.03%]
一种口服降解纳米盔甲辅助益生菌重塑肠道微环境及治疗骨质疏松的方法
Zhiqiang Li,Xueqiang Deng,Chengpeng Qiu et al.
Zhiqiang Li et al.
Improving the intestinal microenvironment and regulating the intestinal flora are highly important in the treatment of osteoporosis. Although previous studies have shown that oral probiotics can prevent or reverse bone loss, their survival ...
Nanopore-based sensing for biomarker detection: from fundamental principles to translational diagnostics [0.03%]
基于纳米孔的生物标志物检测传感技术:从基本原理到转化诊断学
Narlawar Sagar Shrikrishna,Sonu Gandhi
Narlawar Sagar Shrikrishna
Nanopore-based sensing has emerged as a transformative approach for biomarker detection, offering label-free, single-molecule analysis with exceptional sensitivity and specificity. By monitoring ionic current modulations as individual molec...
PDLIM4 drives gastric cancer malignant progression and cisplatin resistance by inhibiting HSP70 ubiquitination and degradation via competitive interaction with STUB1 [0.03%]
PDLIM4通过与STUB1竞争性结合抑制HSP70泛素化降解驱动胃癌恶性进展和顺铂耐药性
Chao Zhu,Meng Chen,Linwei Fan et al.
Chao Zhu et al.
Gastric cancer (GC) frequently shows malignant progression and resistance to chemotherapy due to complex molecular regulatory processes, leading to a poor prognosis. Our study elucidates that PDZ and LIM domain protein 4 (PDLIM4) are highly...