Xu-Da Wang,Qing-Hua Han,Jun Zhang et al.
Xu-Da Wang et al.
Three new triterpenoid saponins, julibrosides A5-A7 (1-3), together with five known saponins (4-8), were isolated from the stem bark of Albizia julibrissin. Their structures were elucidated on the basis of extensive spectroscopic data analy...
A new menthane-type monoterpenoid from fermented Illigera aromatica with Clonostachys rogersoniana 828H2 [0.03%]
伊里格拉芳香草中的一种新型单萜倍半萜烷类化合物
Jian-Wei Dong,Le Cai,Xue-Jiao Li et al.
Jian-Wei Dong et al.
A new menthane-type monoterpenoid, illigerate E (1), as well as two known ones, (1R*,3R*,4S*,6R*)-6,8-dihydroxymenthol (2) and cis-4-hydroxy-5-(1-hydroxy-1-methylethyl)-2-methyl-2-cyclohexene-1-one (3), were isolated from fermented Illigera...
Two new 12-membered macrolides from the endophytic fungal strain Cladosprium colocasiae A801 of Callistemon viminalis [0.03%]
从血藤中分离得到内生真菌Cladosprium colocasiae A801的两个新的十二元大环内酯类化合物
Hong-Xin Liu,Hai-Bo Tan,Sai-Ni Li et al.
Hong-Xin Liu et al.
Two new polyketide metabolites, the 12-membered macrolides 4-hydroxy-12-methyloxacyclododecane-2,5,6-trione (1) and 12-methyloxacyclododecane-2,5,6-trione (2), were isolated from the endophytic fungal strain Cladosprium colocasiae A801 of t...
Potent leishmanicidal and antibacterial metabolites from Olea ferruginea [0.03%]
Oleacein和oleocanthal：Olea ferruginea中具有抗利什曼虫和抗菌作用的代谢产物
Salman Zafar,Faiz -Ur-Rehman,Zafar Ali Shah et al.
Salman Zafar et al.
Inspired from the leishmanicidal and antibacterial potential of the fractions obtained from the crude extract of Olea ferruginea stem, the anti-leishmanial ethyl acetate fraction was subjected to chromatographic separation, leading to the i...
Design, synthesis, and antitumor activity of oleanolic acid derivatives [0.03%]
齐墩果酸衍生物的设计、合成及抗肿瘤活性研究
Yan-Qiu Meng,Zhen-Yu Kuai,Shen-Wen Zhan et al.
Yan-Qiu Meng et al.
Using the techniques of computer-aided drug design, the docking of survivin and known active small molecules was simulated and then the key amino acid residue fragments of the target protein were analyzed. It led to the discovery of active ...
Hong-Xiu Hu,Ran-Ran Gao,Zhao-Hui Gao et al.
Hong-Xiu Hu et al.
Three new (6, 9, and 12) and nine known steroidal saponins were obtained from the fermentation broth of pseudoprotodioscin (PPD) incubated with a fungus Gibberella fujikuroi CGMCC 3.4663. Structures of the metabolites were elucidated by 1-D...
Xiao-Qin Li,Ya-Nan Song,Su-Juan Wang et al.
Xiao-Qin Li et al.
Over the past decades, a number of phytochemicals have been reported to possess potent pharmacological effects. Saikosaponins represent a group of oleanane derivatives, usually as glucosides, which are commonly found in medicinal plants Bup...
Chang Liu,Rong-Rong Cheng,Zhu-Zhen Han et al.
Chang Liu et al.
Nigakialcohol A (1), as unusual cyclization ionone derivative, together with eight known ones (2-9), were isolated from the leaves of Picrasma quassioides (D. Don) Benn (Simaroubaceae). Their structures were elucidated by extensive spectros...
Vasorelaxant effect of quercetin on cerebral basilar artery in vitro and the underlying mechanisms study [0.03%]
槲皮素对基底动脉的 vasorelaxant 效应及机制研究
Tian-Yi Yuan,Zi-Ran Niu,Di Chen et al.
Tian-Yi Yuan et al.
The aim of this study is to investigate the vasorelaxant effect of quercetin on cerebral basilar artery in vitro and provide a preliminary discussion concerning the underlying mechanisms. Using a DMT-isolated micro vessel system, quercetin ...
2-Methyl-versiquinazoline C, a new fumiquinazoline-type alkaloid from the fungus Aspergillus flavipes PJ03-11 [0.03%]
来源于曲霉菌的新倍半萜生物碱2-甲基异戊喹唑啉C
Ying-Ying Si,Ming-Xu Tang,Shuang Lin et al.
Ying-Ying Si et al.
A new fumiquinazoline-type alkaloid 2-methyl-versiquinazoline C (1), together with six known compounds (2-7), was isolated from Aspergillus flavipes PJ03-11 using OSMAC method. Their structures were elucidated on the basis of extensive spec...