Hepatoprotective iridoid glycosides from the aerial parts of Paederia foetida [0.03%]
来源于Paederia foetida的保肝环烯醚萜苷类化合物研究
Wan-Qi Zhang,Xin-Yue Li,Ming-Hui Sun et al.
Wan-Qi Zhang et al.
Two previously undescribed iridoid glycosides, paedoside I (1) and paedoside J (2), were isolated from the aerial parts of Paederia foetida. The structures of these compounds, especially their absolute configurations, were elucidated by com...
Steroidal glycosides from Tylophora ovata with anti-inflammatory and radical scavenging activities [0.03%]
具抗炎和自由基清除作用的Tylophora ovata甾体皂苷成分研究
Bing Shao,Hui Wang,Yu Miao et al.
Bing Shao et al.
A chemical investigation on 80% ethanol extract from the whole plants of Tylophora ovata afforded two new C21 steroidal glycosides, ovatacosides A and B (1 and 2). Structural elucidation of both compounds were performed by spectral methods ...
Signal pathway and active compounds of Penicillium griseofulvum against triple-negative breast cancer [0.03%]
灰黄青霉信号通路及抗三阴性乳腺癌活性成分研究
Di Li,Jun-Guo Huang,Cheng-Yun Huang et al.
Di Li et al.
Triple-negative breast cancer (TNBC) is a type of breast cancer that has a high rate of growth and metastasis. In this study, the liquid fermentation product (EX-9) of Penicillium griseofulvum, an endophytic fungus derived from the medicina...
Antimelanogenesis and antioxidant activity of Broussonetia papyrifera leaf extract fermentation broth [0.03%]
构树叶浸膏发酵液的抗黑色素生成和抗氧化活性研究
Bo Dou,Rui-Qi Wu,Xiao-Lai Ma et al.
Bo Dou et al.
Broussonetia papyrifera leaves are a medicinal plant rich in bioactive substances. This study utilized microbial fermentation of B. papyrifera leaf extract (BLE) to screen out Lactobacillus rhamnosus and Bifidobacterium papyrifera as the mo...
A new nor-28-oleanane glycoside isolated from Syzygium formosum inhibits nitric oxide production in LPS-stimulated RAW264.7 cells [0.03%]
一种来自Syzygium formosum的新型去氧-28-齐墩果烷糖苷通过抑制LPS刺激的RAW264.7细胞中一氧化氮产生发挥抗炎作用
Pham Thi Tham,Pham Thi Thu Giang,Dam Xuan Thang et al.
Pham Thi Tham et al.
One new nor-28-oleanane glycoside (1) and fifteen known compounds (2 - 16) were separated from a methanol extract of Syzygium formosum leaves. Their structures were elucidated via HRESIMS and NMR spectroscopic analyses. The absolute configu...
Methyl jasmonate protects liver and pancreas tissues of adult diabetic rats from STZ-induced oxidative stress damage [0.03%]
甲基茉莉酸保护链脲佐菌素致成年糖尿病大鼠肝胰组织免受氧化应激损伤
Marjan Shabazi,Seifollah Bahramikia,Razieh Kooshki
Marjan Shabazi
This study evaluated the potential of methyl jasmonate (MeJA) to modulate oxidative stress damage and hyperglycemia in rats with STZ-induced diabetes. MeJA treatment (5 and 10 mg/kg) improved the destructive effects of STZ-induced oxidative...
Research on the effects and mechanisms of the Yiqi Huoxue Recipe in improving renal injury in diabetic nephropathy through the HIF-1 pathway [0.03%]
益气活血方通过HIF-1信号通路改善糖尿病肾病肾损伤的效应及机制研究
Wen-Di Niu,Hao-Wei Liang,Lue Hong et al.
Wen-Di Niu et al.
This study investigates the therapeutic effects and mechanisms of the Yiqi Huoxue Recipe (YHR) on renal injury in Diabetic nephropathy (DN). Through mass spectrometry analysis, animal experiments, and network pharmacology approaches, it was...
Discovery of undescribed alkaloids with immunosuppressive activity from the endophytic fungus Penicillium sp. HZ-5 [0.03%]
从内生真菌Penicillium sp. HZ-5中发现具有免疫抑制活性的新结构生物碱类化合物
Jie Li,Ye-Ting Zhang,Yusuf Abudula et al.
Jie Li et al.
Two undescribed alkaloids, mecichorine (1) and talaropyrazine D (2), along with four known compounds were isolated from an endophytic fungus Penicillium sp. HZ-5. Their structures were elucidated from the spectroscopic data. Furthermore, th...
Xin-Li Ma,Wan-Qi Zhang,Jing-Han Zhang et al.
Xin-Li Ma et al.
Two new iridoid glycosides, dasperosides A-B (1-2), together with two known analogues (3-4), were isolated from the air-dried roots of Dipsacus asper. Their structures were established from the spectroscopic data obtained and chemical evide...
Synthesis and antibacterial activity of naringenin derivatives containing selenocyanate moiety [0.03%]
含硒氰酸酯基团的柚皮素衍生物的合成及抗菌活性
Zhi-Ping Liu,Mai-Xia Liu,Chun-Rui Cai et al.
Zhi-Ping Liu et al.
To control plant pathogen infections, we synthesized naringenin derivatives bearing selenocyanate moieties and assayed their antibacterial activity against Xanthomonas axonopodis pv. citri, Xanthomonas oryzae pv. oryzae, and Xanthomonas ory...