A new medermycin analog from the marine-derived actinomycetes Streptomyces sp. ZS-A45 [0.03%]
来自海洋微生物链霉菌ZS-A45的新medermycin类抗生素
Yun Huang,Qing Jiang,Yu-Hong Chen et al.
Yun Huang et al.
A new medermycin analog (1) was isolated from the marine-derived actinomycetes Streptomyces sp. ZS-A45. The structure elucidation of compound 1 was determined by the HRESIMS and extensive NMR analysis. And compound 1 exhibited significant c...
Cucumol B, a new triterpene benzoate from Cucumis melo seeds with cytotoxic effect toward ovarian and human breast adenocarcinoma [0.03%]
黄瓜属植物新成员瓜霉素B及其抗肿瘤作用机制研究
Sabrin Ragab Mohamed Ibrahim,Amgad Ibrahim Mansour Khedr,Gamal Abdallah Mohamed et al.
Sabrin Ragab Mohamed Ibrahim et al.
Phytochemical investigation of the methanolic extract of Cucumis melo L. (Cucurbitaceae) seeds furnished a new triterpene benzoate derivative: cucumol B (1) and four known flavonoids: quercetin-3-O-β-D-glucopyranosyl-(1→6)-α-L-rhamnopyra...
Xu Pang,Na-Na Li,He-Shui Yu et al.
Xu Pang et al.
A phytochemical study on the seeds of Cassia obtusifolia was carried out, which finally led to obtain two naphthalenes (1 and 2), two naphthopyrans (3 and 4) and twelve anthraquinones (5-16). The structures of all compounds were established...
Li-Na Wang,Ling-Ling Qin,Jun-Lin He et al.
Li-Na Wang et al.
Three aryl-tetralin-type lignans, including 2 previously undescribed compounds, were isolated from the root of Sanguisorba officinalis. The structures of the new compounds were elucidated by 1D- and 2D-NMR spectroscopic analyses and mass sp...
Jin-Qian Yu,Xiao-Wei Sun,Zhi-Wei Wang et al.
Jin-Qian Yu et al.
One new quinolinic scandine-type monoterpeniod alkaloid, 3-oxo-scandine (1), as well as seven known ones (2-8), was isolated from the roots of Melodinus henryi. Their structures were elucidated by extensive spectroscopic analysis. All of th...
Bioactive metabolites from the Arctic fungus Nectria sp. B-13 [0.03%]
北极真菌Nectria sp. B-13的生物活性次级代谢产物
Hao-Bing Yu,Heng Jiao,Yu-Ping Zhu et al.
Hao-Bing Yu et al.
Two new cyclohexanone derivatives, nectriatones A-B (1-2), and one new natural product, nectriatone C (3), together with three known phenolic sesquiterpene derivatives (4-6), were isolated from the culture of Nectria sp. B-13 obtained from ...
Kuan Chen,Junbin He,Zhimin Hu et al.
Kuan Chen et al.
Glycosylation is an effective approach to improve the druggability of natural products by increasing their water solubility. In this work, we report the glycosylation of oleanane-type triterpenoids by a recombinant microbial glycosyltransfe...
Jin-Long Tian,Chen-Xi Li,Xin-Yue Shang et al.
Jin-Long Tian et al.
Phytochemical investigation of Croton crassifolius roots afforded five sesquiterpenes (1-5), including two new sesquiterpenes 6S-hydroxy-cyperenoic acid (1) and crassifterpenoid A (5), together with three known compounds (2-4). The structur...
New polyacetylenes glycoside from Eclipta prostrate with DGAT inhibitory activity [0.03%]
具DGAT抑制活性的地不容多炔茋苷类化合物的研究
Xiao Meng,Ban-Ban Li,Xin Lin et al.
Xiao Meng et al.
One new polyacetylene glycoside eprostrata Ⅰ (1), together with seven known compounds (2-8), were isolated from Eclipta prostrata. Their structures were elucidated on the basis of spectroscopic and physico-chemical analyses. All the isolat...
Cheng Tang,Ya-Ming Yu,Qing-Ling Qi et al.
Cheng Tang et al.
Four new steroidal saponins, 3-O-β-D-glucopyranosyl(1→4)-β-D-fucopyranosyl -(25R)-spirost-5-en-3β,17α-diol (1), 3-O-β-D-glucopyranosyl(1→4)-β-D- fucopyranosyl-(25S)-spirost-5-en-3β,17α-diol (2), 3-O-β-D-glucopyranosyl(1→2) -β-D...