Chang-Ling Duan,Yu-Juan Li,Feng-Yun Wang et al.
Chang-Ling Duan et al.
Two new steroidal glycosides (named fibrophiopogonins A, B), along with one known glycoside, were isolated from the fibrous roots of Ophiopogon japonicus (Liliaceae). Comprehensive spectroscopic analysis, including 2D NMR spectroscopy, and ...
Lu-Ning Li,Lei Wang,Xiu-Li Guo
Lu-Ning Li
Two new compounds herialpins A-B (1-2), along with eleven known compounds, were isolated from the culture of fungus Hericium alpestre. The structures were elucidated by 1D and 2D NMR data, ESI-MS and X-ray crystallographic analysis. Compoun...
Transcriptome analysis of three cultivars of Poria cocos reveals genes related to the biosynthesis of polysaccharides [0.03%]
三株猪苓转录组分析揭示多糖合成相关基因
Lan Yang,Juan Tang,Jin-Jun Chen et al.
Lan Yang et al.
Poria cocos (P. cocos) polysaccharides (PCPs) are used to improve immunity and possess antitumor activities. We compared three cultivars of P. cocos (5.78, XJ 28 and JHYH) PCP contents. Then we determined that malZ, galA, SORD, gnl and bglX...
Cytotoxic lanostane triterpenoids from the stems of Schisandra glaucescens [0.03%]
施木果茎的细胞毒型羊毛脂烷三萜类化合物
Yan Liu,Jiang Hu,Yan Lv et al.
Yan Liu et al.
Phytochemical investigation on the stems of Schisandra glaucescens resulted into the isolation of three new lanostane triterpenoids, 12-hydroxyschiglausin B (1), 12-hydroxykadsuphilactone B (2), and 20R-hydroxyschinalactone C (3). Structura...
Two new tetracyclic triterpenoids from the endophytic fungus Hypoxylon sp. 6269 [0.03%]
六链霉菌发酵产物中新四环茋类化合物的研究
Han-Qiao Liang,Da-Wei Zhang,Shun-Xing Guo et al.
Han-Qiao Liang et al.
Two new tetracyclic triterpenoids, integracide E (1) and isointegracide E (2), as well as three known secondary metabolites (i.e. integracide A (3), 2-deoxyintegracide A (4) and 2-deoxyintegracide B (5)), were isolated from mycelium of the ...
Anti-inflammatory diterpenes from the fruits of Vitex trifolia L. var. simplicifolia Cham [0.03%]
尖叶 chastetree 果实中的抗炎二萜类化合物
Shi-Ming Fang,Rui Liu,Lin Li et al.
Shi-Ming Fang et al.
Two new labdane-type diterpenes, named viterotulin C (1) and vitexilactone D (2), together with five known diterpenes (3-7), were isolated from the fruits of Vitex trifolia L. var. simplicifolia Cham. Their structures were elucidated by det...
Two pairs of phenylpropanoid enantiomers from the leaves of Eucommia ulmoides [0.03%]
杜仲叶中苯丙素类对映体异构体的分离鉴定
Xu-Liu Shi,Jian-Kun Yan,Wen-Kai Li et al.
Xu-Liu Shi et al.
Two pairs of phenylpropanoid enantiomers, (+)-(7S,8S)-alatusol D (1a), (-)-(7R,8R)-alatusol D (1b), (-)-(7S,8R)-alatusol D (2a) and (+)-(7R,8S)-alatusol D (2b) were isolated from the leaves of Eucommia ulmoides Oliver. Among them, 1a and 2b...
Synthesis and evaluation of coumarin/1,2,4-oxadiazole hybrids as selective BChE inhibitors with neuroprotective activity [0.03%]
具有神经保护作用的选择性BChE抑制剂肉桂内酯/1,2,4-噁二唑杂化物的合成与评估
Juan Zhang,Jia-Cheng Li,Jia-Li Song et al.
Juan Zhang et al.
A series of new coumarin/1,2,4-oxadiazole hybrids were synthesized and evaluated for cholinesterase inhibitory and neuroprotective activities. Among them, enantiomers 5u and 5v showed potent hBChE inhibitory activity with IC50 values of 8.1...
Enzymatic synthesis of glucuronidated metabolites of two neurological active agents using plant glucuronosyltransferases [0.03%]
利用植物葡萄糖醛酸转移酶合成两种神经活性药物的葡糖醛酸代谢物的酶法研究
Tian Yue,Ke-Bo Xie,Zhen Tan et al.
Tian Yue et al.
Glucuronidation is an important and popular metabolic reaction in vivo of drugs. The further evaluation of biological activity and toxicity of glucuronides is necessary in the course of the drug research and development. However, the synthe...
Nimbandiolactone-21 and nimbandioloxyfuran, two new 28-norlimonoids from the leaves of Azadirachta indica (Meliaceae) [0.03%]
来自尼帕树（苦木科）的两种新的28- norlimonoids：Nimbandiolactone-21和Nimbandioloxyfuran
Nhi Y Thi Nguyen,Phu Hoang Dang,Van Truong Thien Nguyen et al.
Nhi Y Thi Nguyen et al.
From an EtOAc-soluble fraction of the leaves of Azadirachta indica, two new 28-norlimonoids named nimbandiolactone-21 (1) and nimbandioloxyfuran (2), together with nimbandiolactone-23 (3), were isolated. Their relative structures were eluci...