Jing Lu,Wei-Hua Wang,Qiang-Qiang Shi et al.
Jing Lu et al.
A new alkaloid, (E)-3-(3-methyl-1-oxo-2-butenyl)-6-methoxy-1 H -indole (1), along with two known ones, was isolated from the aerial parts of Cimicifuga heracleifolia. The structure of 1 was elucidated on the basis of extensive spectroscopic...
Two new sesquiterpenes produced by the endophytic fungus Aspergillus fumigatus from Ligusticum wallichii [0.03%]
isolation and identification of two new sesquiterpenes produced by内生真菌aspergillus fumigatus from ligusticum wallichii根中的研究
Sha Li,Jin-Feng Chen,Ling-Ling Qin et al.
Sha Li et al.
Two previously undescribed sesquiterpenes along with nine known compounds were isolated from the fermentation broth of Aspergillus fumigatus, an endophyte of Ligusticum wallichii. Their structures were elucidated through extensive spectrosc...
Santin inhibits influenza A virus replication through regulating MAPKs and NF-κB pathways [0.03%]
Santin通过调节MAPKs和NF-κB途径抑制A型流感病毒复制
Ming Zhong,Hui-Qiang Wang,Hai-Yan Yan et al.
Ming Zhong et al.
Influenza A virus (IAV) causes high morbidity and significant mortality worldwide. Given the limitations of existing vaccination and antiviral drugs, it is urgent to develop new anti-influenza drugs. Flavonoids are natural polyphenolic comp...
Pu-Ming Zhang,Zhi-Bo Wu,Chen Zhang et al.
Pu-Ming Zhang et al.
Two new chromene derivatives, songaricachromenes A (1) and B (2), were isolated from Artemisia songarica, along with 10 known compounds (3-12). The structures and stereochemistry of the new compounds were elucidated by analyses of the NMR, ...
Four new C19-diterpenoid alkaloids from Aconitum hemsleyanum var. circinatum [0.03%]
四种新C19二萜类生物碱化合物及其制备方法和应用
Dan He,Wang-Yan Liu,Jiao Xiong et al.
Dan He et al.
Four new C19-diterpenoid alkaloids, hemaconitines A-D (1-4), were isolated from the roots of Aconitum hemsleyanum var. circinatum. Their structures were elucidated as 19R-hydroxyl-secoyunnaconitine (1), (3R)-hydroxyl-liwaconitine (2), 14-an...
New abietane diterpenoid glucosides from underground parts of Isodon taliensis [0.03%]
毛瓣香茶菜地下部分中新梓醇衍生物的研究
Pan Xiang,Chao-Jiang Xiao,Wei Xu et al.
Pan Xiang et al.
Two new abietane diterpenoid glucosides, talienosides A and B (1 and 2), along with four known compounds (3 - 6), were isolated from the ethyl acetate soluble portion of 70% acetone extract of the underground parts of Isodon taliensis. Thei...
Efficacy of phospholipidated curcumin in nonalcoholic fatty liver disease: a clinical study [0.03%]
磷脂结合姜黄素治疗非酒精性脂肪肝病的临床疗效研究
Yunes Panahi,Parisa Kianpour,Reza Mohtashami et al.
Yunes Panahi et al.
Curcumin is a safe and dietary phytochemical that can improve different pathophysiologic features of non-alcoholic fatty liver disease (NAFLD). Here, we investigated the efficacy of phospholipidated curcumin supplementation in NAFLD patient...
(-)-Calcaridine B, a new chiral aminoimidazole-containing alkaloid from the marine sponge Leucetta chagosensis [0.03%]
来自海葵Leucetta chagosensis的新的手性氨基酸酰胺类生物碱（-）-Calcaridine B
Wei-Zhuo Tang,Zhong-Zhen Yang,Fan Sun et al.
Wei-Zhuo Tang et al.
LC-DAD/MS-based dereplication of organic extract of a calcareous sponge Leucetta chagosensis afforded one new chiral aminoimidazole-containing alkaloid, (-)-calcaridine B (1), along with one achiral imidazole analog leucettamine E (2) as we...
Jia-Meng Dai,Yan-Hong Li,Xiao-Yun Pu et al.
Jia-Meng Dai et al.
Phytochemical investigation on Hemiphragma heterophyllum led to the isolation of two new compounds, heterophyllumin A (1) and heterophylliol (3), along with nine known compounds, (‒)-sibiricumin A (2), iridolactone (4), jatamanin A (5), di...
Re-engineering and synthesis of cytotoxic 2,3:7,8-di(alkylenedioxy)-extended analogs of quaternary sanguinarine chloride [0.03%]
二次胺桥连接的四甲基血根碱类似物的设计、合成及构效关系研究
Qi-Lin Li,An-Jun Deng,Ming Ji et al.
Qi-Lin Li et al.
A method was developed to synthesize 2,3:7,8-di(alkylenedioxy)-extended analogs of quaternary sanguinarine chloride. 1-Bromo-2-bromomethyl-3,4-alkylenedioxy benzenes and 6,7-alkylenedioxynaphthalen-1-amines were synthesized first. Reactions...