Gui-Lian Liu,Wei Xu,Xin-Juan Liu et al.
Gui-Lian Liu et al.
Phytochemical investigation on the leaves of Rabdosia serra led to the isolation of two new abietane diterpenoids, raserranes A (1) and B (2), and four known phenylpropanoids (3-6). Their structures were determined by spectroscopic data. Co...
Two new compounds from the roots of Pueraria peduncularis and their molluscicidal effects on Pomacea canaliculata [0.03%]
两张瓣毛花豆根的新成分及其对福寿螺的杀螺效果研究
Hua-Bao Chen,Tian-Xing Lv,Ming Zhang et al.
Hua-Bao Chen et al.
Two oleanane-type triterpenoid saponins named pedunsaponin D (1) and pedunsaponin E (2) were isolated from the roots of Pueraria peduncularis. The structures of the new compounds were elucidated based on chemical and physicochemical evidenc...
Ursane-type triterpenoids from the roots of Rosa multiflora with their anti-inflammatory activity [0.03%]
多花玫瑰根部ursane型三萜及其抗炎活性
Hai Jiang,Hua Han,Wen-Jing Man et al.
Hai Jiang et al.
Nine ursane-type triterpenoids including three new ones 2α, 19α-dihydroxyurs-3-O-acetyltormentic acid (1), 1α, 2α, 3α, 20β-tetrahydroxyurs -13(18)-en-28-oic acid (2), and 2α, 3α, 20β, 24-tetrahydroxyurs-13(18)-en-28-oic acid (3) we...
Novel liquid fermentation medium of Cordyceps militaris and optimization of hydrothermal reflux extraction of cordycepin [0.03%]
虫草素液体发酵培养基的创新及超声辅助溶剂萃取工艺优化研究
Qing-Ying Luo,Hong-Fu Cao,Shu-Kun Liu et al.
Qing-Ying Luo et al.
In this study, we developed a novel liquid fermentation medium of Cordyceps militaris using pupa powder and wheat bran as nitrogen resources instead of the traditionally used peptone. This process not only reduced the cost by approximately ...
Synthesis and biological evaluation of novel biphenyl-furocoumarin derivatives as vasodilator agents [0.03%]
新型联苯呋喃香豆素衍生物作为血管扩张剂的合成及其生物活性评价
Di Wei,Ya-Jing Hou,Yi-Tong Xie et al.
Di Wei et al.
A series of novel biphenyl-furocoumarin derivatives were synthesized based on the nuclear structure of imperatorin and identified by IR, 1H NMR, 13C NMR and MS, and evaluated for their ability to relax vessel on isolated rat mesenteric arte...
Pharmacokinetics and acetylcholine releasing effects of ginsenoside Rg1 in hippocampus of beta-amyloid model rats [0.03%]
红参皂苷Rg1的药动学及其对β淀粉样蛋白模型大鼠海马乙酰胆碱释放的影响研究
Yang Liu,Yan Gao,Ke-Xin Li et al.
Yang Liu et al.
This study aimed at investigating the pharmacokinetics (PK) and acetylcholine (Ach) releasing effects of ginsenoside Rg1 in hippocampus (HIP) of soluble oligomeric assemblies of amyloid beta (ADDLs) induced Alzheimer's disease (AD) model ra...
Coixlachryside B: a new benzoxazinoid glycoside from the roots of Coix lachryma-jobi var. ma-yuen (Gramineae) [0.03%]
毛脉茅根素B：牻牛儿苗属植物毛叶狗尾草根中的一种新的苯并咯嗪醇糖苷类成分
Yun-Hyeok Choi,Chun Whan Choi,Seong Hyun Hong et al.
Yun-Hyeok Choi et al.
Coix lachryma-jobi L. var. ma-yuen has been a source of food and traditional folk medicine in some parts of Asia for thousands of years; however, the roots of this plant have not been phytochemically investigated. Herein, we report the isol...
A new dihydrophenanthrene from Cymbidium finlaysonianum and structure revision of cymbinodin-A [0.03%]
从卡特兰属斑点兰中得到一个新的二氢菲类倍半萜及对cymbinodin-A结构的修正
Nonthalert Lertnitikul,Chutichot Pattamadilok,Chaisak Chansriniyom et al.
Nonthalert Lertnitikul et al.
1-(4-Hydroxybenzyl)-4,6-dimethoxy-9,10-dihydrophenanthrene-2,7-diol (13), a new dihydrophenanthrene, was isolated along with ferulic acid esters (1), eight phenanthrene derivatives (2, 3, 6-11) and three bibenzyls (4, 5, 12) from an epiphyt...
Two new dammarane triterpenes isolated from Cleome khorassanica Bunge & Bien with cytotoxicity against DU-145 and LNCaP prostate cancer cell lines [0.03%]
两种来自Cleome khorassanica Bunge &Bien的具有抗前列腺癌活性的新倍半萜成分研究
Seyed-Ebrahim Sajjadi,Mustafa Ghanadian,Mahmoud Aghaei et al.
Seyed-Ebrahim Sajjadi et al.
From the aerial parts of Cleome khorassanica Bunge & Bien, a new 3-oxo-4-oxa-A-homo-25,26,27-trinordammarano-24,20-lactone triterpene (1), a new natural product 20,25-dihydroxy-3-oxodammarane triterpene (2), together with known 5-hydroxy-3,...
Hsp90β inhibitors prevent GLT-1 degradation but have no beneficial efficacy on absence epilepsy [0.03%]
Hsp90β抑制剂阻止GLT-1降解但对失神癫痫没有治疗效果
Yu-Chen Peng,Shan Wang,Yong Zhang et al.
Yu-Chen Peng et al.
The loss of glutamate transporter-1 (GLT-1) is associated with temporal lobe epilepsy (TLE). A recent study reported that Hsp90β interacted with GLT-1 and recruited it to 20S proteasome for degradation. Therefore, inhibiting Hsp90β may be...