The extremophiles-derived secondary metabolites for antitumor and antibacterial therapy [0.03%]
极端环境微生物次生代谢产物的抗肿瘤和抗菌研究进展
Ru-Ling Zhang,Yan-Ni Wang,Li-Min Jin et al.
Ru-Ling Zhang et al.
Extreme environments shape microbial diversity and drive distinctive physicobiochemical strategies. Secondary metabolites from extremophiles represent novel bioactive compounds with unique mechanisms of action, offering promising avenues fo...
Gurjeet Kaur,Rupali Chauhan,Gauri Kashyap et al.
Gurjeet Kaur et al.
This evidence-based review highlights the cardioprotective potential of punicalagin, a major polyphenolic ellagitannin from Punica granatum L., focusing on its pharmacological mechanisms in cardiovascular disease (CVD) pathogenesis. Preclin...
Strepamrisides C and D: two new rhamnosides from Streptomyces amritsarensis 13-85 [0.03%]
来自链霉菌属的新鼠李糖苷类成分Strepamrisides C和D
Ming-Xuan Zhao,Guo-Dong Liang,Jing-Shuai Wu et al.
Ming-Xuan Zhao et al.
Two new rhamnosides, strepamrisides C and D (1 and 2), together with two known rhamnosides, maculosin-O-α-L-rhamnopyranoside (3) and 2-pyrrolylcarbonyl-α-L-rhamnopyranoside (4) were isolated from Streptomyces amritsarensis 13-85. Their st...
Five new cassane diterpenoids from the seeds of Pterolobium macropterum [0.03%]
来自Pterolobium macropterum种子的五个新的卡桑二萜化合物
Yi-Hui Li,Gang Ke,Yue-Ping Lan et al.
Yi-Hui Li et al.
Five undescribed cassane diterpenoids were obtained from the seeds of Pterolobium macropterum. Their structures were established through extensive 1D and 2D NMR spectroscopy, and mass spectrometry. Their absolute configurations were assigne...
Chemical constituents of the seeds of Citrus reticulata and their bioactivity [0.03%]
粗橙子种子的化学成分及其生物活性研究
Meng-Jue Rui,Hong-Tao Xu,Jun-Jie Yang et al.
Meng-Jue Rui et al.
Four new limonoids (1-4), reticulactone A (1), 21,23-dihydro-23-ethoxy-21-oxolimonin (2), tetrahydro-20,22-dihydroxy-21,23-diethoxy-nomilin (3), and dasycarinone B (4), as well as 11 known limonoids and one known carbolic acid, were isolate...
Transcriptomic profile and gene expression of human breast cancer cell lines treated with herbal extract of clinacanthus nutans leaves [0.03%]
金丝草叶提取物处理的人乳腺癌细胞系的转录组谱型和基因表达模式
Zaleha Md Toha,Norhasyimah Haron,Kristine Sandra Pey Adum et al.
Zaleha Md Toha et al.
Clinacanthus nutans (CN) is traditionally used in medicine, but its apoptotic effects on breast cancer cells remain unclear. This study investigated the apoptotic potential of CN dichloromethane leaf extract (CNDCM) in MCF-7 cells using RNA...
Qian-Ru Wang,Shu-Yang Wang,Shuang-Gang Ma et al.
Qian-Ru Wang et al.
New α-glucosidase inhibitory isoflavone derivatives from the leaves of Placolobium vietnamense [0.03%]
越南合萌叶中α-葡萄糖苷酶抑制异黄酮衍生物的研究
Tuyet T N Huynh,Huong T M Nguyen,Quyen H N Tran et al.
Tuyet T N Huynh et al.
A new isoflavone-quinone, placovinone E (1), and a new natural isoflavone, placovinone F (2), together with four known isoflavones (3-6), were isolated from the leaves of P. vietnamense. The chemical structures of all isolated compounds wer...
Antifungal secondary metabolites from a mangrove-derived fungus Daldinia eschscholtzii TGM23 [0.03%]
一种产于红树植物上的Daldinia eschscholtzii TGM23真菌的抗真菌次生代谢产物
Xiu Gong,Wei-Kang Chen,Miao Yu et al.
Xiu Gong et al.
One new compound daldiniaone A (1), along with six known compounds 1-(2,6-dihydroxyphenyl)ethan-1-one (2), 1-(2,6-dihydroxyphenyl)butan-1-one (3), penicilliode B (4), (4-hydroxy-3-methoxyphenyl)acetic acid (5), 2-(4-methoxyphenyl)acetic aci...
An integrative strategy for comprehensive determination of nineteen constituents from Eupatorii Herba and application in pharmacokinetic study by combing UHPLC-QTRAP-MS/MS with gC-MS [0.03%]
结合UHPLC-QTRAP-MS/MS和gC-MS联用全面测定夏枯草药材中19个成分及应用其药代动力学研究的整合策略
Kai-Li Zhang,Zi-Jing Zhang,Zhou-Jing Feng et al.
Kai-Li Zhang et al.
This study developed an integrated ultra-high performance liquid chromatography triple quadrupole linear ion trap tandem mass spectrometry/tandem mass spectrometry (UHPLC-QTRAP-MS/MS) with gas chromatography-mass spectrometry (GC-MS) strate...