Salidroside attenuates sepsis-induced acute kidney injury by inhibiting ferroptosis [0.03%]
山柳桃素通过抑制铁死亡减轻脓毒症急性肾损伤
Ling-Ling Zhen,Ming-Tong Hou,Sheng-Bao Wang
Ling-Ling Zhen
Salidroside is a traditional Chinese medicine with multiple pharmacological activities such as anti-inflammatory and antioxidant properties, while acute kidney injury (AKI) is a common sepsis-induced acute inflammatory response. Using trans...
Discovery of immunosuppressive secondary metabolites from Hypericum patulum [0.03%]
从黄花岩黄芪中发现免疫抑制性次生代谢物
Fei Song,Jie Li,Bin-Bin Song et al.
Fei Song et al.
The chemical study of Hypericum patulum provided a new degraded lupane-type triterpenoid, patutriter A (1), and seven known compounds (2-8). Their structures were identified by spectroscopic techniques and single crystal diffraction experim...
Shaoyao-Gancao decoction improves dyslipidemia in rats with polycystic ovary syndrome by reshaping the gut microbiota and regulating the bile acid/FXR pathway [0.03%]
芍药甘草汤通过重塑肠道微生物群和调节胆汁酸/FXR通路改善多囊卵巢综合征大鼠的血脂异常
Jia-Qi Duan,Yi-Fan Sun,Xin Wang et al.
Jia-Qi Duan et al.
This study aims to investigate the potential mechanism of Shaoyao-Gancao Decoction (SGD) in treating polycystic ovary syndrome (PCOS). Our results suggested that SGD effectively regulated estrous cycles, reduced body weight and serum lipid ...
Baicalein: unveiling the multifaceted marvel of hepatoprotection and beyond [0.03%]
黄芩素：揭开其在保肝及更多领域的多重功效之谜
Ashish Dogra
Ashish Dogra
Flavonoids are bioactive compounds derived from plants that play a crucial role in human health. Baicalein is a prominent phytoconstituent with multifaceted therapeutic potential against various diseases. This review explores recent advance...
New polyketides from the mangrove-associated endophytic fungus Phomopsis sp. DHS-11 [0.03%]
来自红树内生真菌DHS-11的新型聚酮化合物
Zhi-Kai Guo,Bi-Ting Chen,Dan-Dan Chen et al.
Zhi-Kai Guo et al.
Chemical investigation of the mangrove-derived fungus Phomopsis sp. DHS-11 led to the isolation of three new pyrone derivatives (1-3), and a new natural product (4). Their structures were identified by NMR spectroscopy and mass spectrometry...
Design, synthesis and antitumor activity of pentacyclic triterpenoid ursolic acid derivatives and oleanolic acid derivatives based on multi-target [0.03%]
五环三萜乌索酸衍生物和齐敦果酸衍生物的设计、合成及多靶点抗肿瘤活性研究
Jun-Jiao Ma,Liang-Feng Zhang,Dong-Ping Xu et al.
Jun-Jiao Ma et al.
Totally twelve inhibitors of Survivin and Sp1 based on ursolic acid (UA) derivatives and oleanolic acid (OA) derivatives were designed and synthesized with modification at C-2, C-3 and C-28 of UA and OA. Their structures were confirmed by H...
Two new bergamotane-type sesquiterpeniods from the plant endophytic fungus Paraconiothyrium brasiliense [0.03%]
来自植物内生真菌巴西型小丛壳的两种新型伯格莫特烷型倍半萜类化合物
Ying Shi,Ling Liu
Ying Shi
One new bergamotane-type sesquiterpeniod lactam brasilactam A (1) and one new bergamotane-type sesquiterpeniod spiroketal lactone brasiketalolide A (2), along with two known compounds ampullicin (3) and isoampullicin (4) were isolated from ...
Alkaloids from cigar [0.03%]
雪茄中的生物碱
Qing-Yang Wu,Guang-Hai Zhang,Feng Wei et al.
Qing-Yang Wu et al.
Phytochemical investigation on cigar tobacco led to identification of 16 alkaloids including two undescribed nicotine dimeric analogs, cigatobines A-B (1-2), as well as new natural products pyridylnicotine (3), cis-5'-(2-oxopropyl)-nicotine...
Unlocking the potential of Radix Astragali and its active ingredients in gastric ulcer therapy [0.03%]
黄芪及其有效成分在胃溃疡治疗中的潜能探索
Pei-Pei Zhang,Jing-Ni Tang,Bo-Yu Xiang et al.
Pei-Pei Zhang et al.
We studied the protective effects of Radix Astragali (RA) on gastric ulcer (GU). A literature search was conducted using databases from Web of Science, PubMed, Springer, ScienceDirect, Science Direct Chinese National Knowledge Infrastructur...
Functional and biological characterization of Lactobacillus plantarum with isatin for use as probiotics for therapeutic options [0.03%]
具有吲哚青的植物乳杆菌的功能和生物特性鉴定作为治疗性的益生菌选项
Ramya Ravindhiran,Mahalakshmi Subramanian,Madhumitha Rajalingam et al.
Ramya Ravindhiran et al.
In our study, the functional and biological properties of the developed probiotic formulations containing Lactobacillus plantarum and isatin (Couroupita guianensis) have been evaluated. The developed probiotic formulations have demonstrated...