Biotransformation and metabolite activity analysis of flavonoids from propolis in vivo [0.03%]
蜂胶中黄酮类化合物的体内生物转化及代谢产物活性分析
Gang Liu,Cui-Ping Zhang,Yuan-Yuan Lu et al.
Gang Liu et al.
Propolis is a natural resinous compound produced by bees, mixed with their saliva and wax, and has a range of biological benefits, including antioxidant and anti-inflammatory effects. This article reviews the in vivo transformation of propo...
Chemical constituents from the leaves and branches of Wikstroemia chamaedaphne with their activation of latent HIV activities [0.03%]
Wikstroemia chamaedaphne叶子和茎枝中的化学成分及其激活潜伏HIV活性的作用
Yun-Xia Wei,Ya-Ting Li,Li-Wei Zhang et al.
Yun-Xia Wei et al.
A new compound, named coniferin B (1), and fourteen known compounds were purified and identified from the leaves and branches of Wikstroemia chamaedaphne Meisn. Their chemical structures were elucidated through analyzing spectroscopic and H...
Regulation of Fuzheng Huayu capsule on inhibiting the fibrosis-associated hepatocellular carcinogenesis [0.03%]
扶正化瘀胶囊对肝纤维化相关肝癌发生抑制作用的调控研究
Wen-Qi Zhang,Jia-Xin Sun,Shu-Ting Lan et al.
Wen-Qi Zhang et al.
In the current study, bioinformatics analysis of the hepatocellular carcinoma (HCC) dataset was conducted with the hepatoprotective effect of the Fuzheng Huayu (FZHY) capsule against the diethylnitrosamine-induced HCC progression analyzed. ...
Macrophorins H and L, two new HMG-conjugate macrophorins from rihzospheric Penicillium sp. NX-05-G-3 [0.03%]
来源于根围Penicillium sp. NX-05-G-3的两个新的HMG-连接大酚类化合物MACROPHORINS H和L
Xiao-Long Tang,Kai Ran,Bo-Chu Wang et al.
Xiao-Long Tang et al.
Macrophorins H (4) and L (5), two rare HMG-conjugate macrophorins along with three known macrophorins (1-3), three DMOA-derived meroterpenoids (6-8) and two ergosterol derivates (9-10) were isolated from sterilized rice medium cultured Peni...
Dang Viet Cuong,Tran Thi Hong Hanh,Pham Thi Mai Huong et al.
Dang Viet Cuong et al.
Using various chromatographic separations, six glycoside derivatives (1-6), including one new ent-labdane glucoside named cayratioside (1), were isolated from the methanol extract of Cayratia geniculata stems and leaves. Their structures we...
Secofumitremorgins C and D, a pair of atropisomers from saltern-derived fungus Aspergillus fumigatus GXIMD00544 [0.03%]
来自盐场分离得到的曲霉菌GXIMD00544中的Secofumitremorgins C和D一对对映异构体化合物
Geng-Si Zhang,Hai-Yan Li,Li-Fen Liang et al.
Geng-Si Zhang et al.
A pair of atropisomers secofumitremorgins C (1a) and D (1b), together with fifteen known alkaloids (2-16), were isolated from a saltern-derived fungus Aspergillus fumigatus GXIMD00544. The structures of atropisomers 1a and 1b were elucidate...
Effects of psoralidin on the expression of glutamate decarboxylases and inhibitory synapse development [0.03%]
光敏感蛋白psoralidin对谷氨酸脱羧酶表达和抑制性突触发育的影响
Seong-Eun Lee,Gum Hwa Lee
Seong-Eun Lee
Gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter required for excitation/inhibition balance is synthesized by the glutamic acid decarboxylases (GADs) in GABAergic neurons. The levels and activity of GADs are strongly corr...
Development of natural perfume as potential fungicide candidates: construction and biological evaluation of vanillin analogs bearing the 1,3,4-oxadiazole/1,3-thiazolidin-4-one fragments [0.03%]
作为潜在杀菌剂的天然香料的发展：苦味化合物1,3,4-噁二唑/1,3-噻唑烷-4-酮片段的构建和生物评价
Cheng-Ran Zhang,Si-Qi Wei,Xiao-Yan Zhi et al.
Cheng-Ran Zhang et al.
Two series of vanillin derivatives containing 1,3,4-oxadiazole and 1,3-thiazolidin-4-one scaffolds were prepared and evaluated for their antifungal activity. The results revealed that compounds 6j (29.73 μg/ml) and 7a (38.15 μg/ml) displa...
Two new jatrophane diterpenoids from Euphorbia helioscopia with activity towards autophagic flux [0.03%]
两种具有自噬通量活性的乳香烷二萜从牻牛儿苗中获得
Ming-You Peng,Xiong Zhang,Qin-Dan Li et al.
Ming-You Peng et al.
Nine jatrophane diterpenoids were isolated from the whole plant Euphorbia helioscopia, including two new ones, helioscopnins A (1) and B (2). Comprehensive spectroscopic data analysis and ECD calculations elucidated their structures, includ...
Quan-Yu Yang,Song-Xue Yang,Qiong Wei et al.
Quan-Yu Yang et al.
Two new triterpenes mayteneri A (1), mayteneri B (2), and seven known compounds (3-9) were isolated from stems of Maytenus hookeri Loes. The chemical structures of compounds 1 and 2 were established by 1D, 2D NMR, HRESIMS analysis, and calc...