Suaeglaucin C: a new coumaronochromone isolated from Suaeda glauca [0.03%]
来自Suaeda glauca的新的香豆酮化合物Suaeglaucin C
Jia Jia,Xian-Rui Ding,Xiao-Han Zang et al.
Jia Jia et al.
A new coumaronochromone (1), and 12 known compounds (2-13) were isolated from the ethyl acetate part of an aqueous EtOH extract of Suaeda glauca. Compounds 5-8 and 12 effectively ameliorated pericardial edema and venous congestion in zebraf...
In vivo antiulcerogenic effect of morinda elliptica stem extract against ethanol-induced gastric ulcer in rat [0.03%]
摩鲁拉椭圆花茎的抗溃疡效果研究
Suhayla H Shareef,Khaled A Ahmed,Tola A Faraj et al.
Suhayla H Shareef et al.
This study aims to evaluate the gastroprotective effects of M. elliptica stem on ethanol-induced stomach damage. Thirty rats were randomly divided into five groups. The groups treated with M. elliptica showed reduced stomach injuries, incre...
Lobelia chinensis extract suppresses osteoclast differentiation through dual inhibition of JNK/nF-κB and btk/PLCγ2 pathways [0.03%]
远志皂苷通过抑制JNK/NF-κB和BTK/PLCγ2信号通路体外抑制破骨细胞分化
Ju-Young Kim,Yoon-Hee Cheon,Chang Hoon Lee et al.
Ju-Young Kim et al.
Osteoporosis is characterized by excessive bone resorption due to aberrant osteoclast activation. This study investigated the effects of Lobelia chinensis extract (L.C.) on receptor activator of nuclear factor-κB ligand (RANKL)-induced ost...
Withaferin A in breast cancer therapy: multi-targeted modulation of redox homeostasis, autophagy, and apoptosis [0.03%]
有丝分裂素类似物在乳腺癌治疗中的作用：红ox平衡、自噬和凋亡的多靶点调节
Neeraj Patel,Aditi Gupta,Riya Mishra et al.
Neeraj Patel et al.
Withaferin A (WA), a steroidal lactone from Withania somnifera, exerts multi-targeted anti-breast-cancer activity by modulating redox homeostasis, autophagy, and apoptosis. WA elevates reactive oxygen species, perturbs mitochondrial functio...
Kuwanon C alleviates pulmonary fibrosis via activation of the Nrf2 signaling pathway [0.03%]
Kuwanon C通过激活Nrf2信号通路缓解肺纤维化
Qian Wang,Teng-Fei Wan,Lu Ren et al.
Qian Wang et al.
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease lacking effective therapies. To investigate antifibrotic potential and mechanisms of kuwanon C, we evaluated its effects in bleomycin-induced IPF and TGF-β1-stimulated myofi...
Xiao-Ying Li,Bo Pang,Zhi-Cheng Yao et al.
Xiao-Ying Li et al.
Three undescribed compounds including (8S)-neonardochinone B (1), (2E,4E,6E)-4-methylocta-2,4,6-trienedioic acid (2) and narchinol D (3), along with three known sesquiterpenoids kanshone A (4), kanshone K (5) and kanshone L (6) were isolate...
Three new iridoid glycosides from the roots of Nardostachys jatamansi [0.03%]
Nardostachys jatamansi的根中三-new- iridoidglycoside化合物
Si-Yuan Liu,Xiao-Ying Li,Huai-Xiu Wen et al.
Si-Yuan Liu et al.
In this study, the phytochemical profile of the roots of Nardostachys jatamansi was investigated, leading to the isolation of four iridoid glycosides, including three new compounds: 2"-acetyl-valerosidate (1), 3"-acetyl-valerosidate (2), 10...
Juan Liu,Zhi-Wen Yue,Si-Jia Yan et al.
Juan Liu et al.
Phytochemical investigation of Ferula sinkiangensis K. M. Shen led to the isolation of 12 meroterpenoids, including three new compounds (1-3) and nine known compounds (4-12). Their structures were elucidated based on comprehensive spectrosc...
Clinacanthus nutans in modern therapeutics: pharmacological insights and emerging clinical applications [0.03%]
Clinacanthus nutans的现代治疗作用：药理学见解和新兴临床应用
Yi-Le Cheng,Liang Cao,Muhammad Majid et al.
Yi-Le Cheng et al.
Clinacanthus nutans (CN), a traditional medicinal plant widely used in Southeast Asia, has gained attention as a potential nutraceutical and therapeutic agent due to its diverse phytochemical composition, including phenolics, flavonoids, te...
Citronellal improves ischemia-induced pathological senescence of hippocampal neurons and cognitive impairment via regulation of the TRPM2/NMDAR pathway [0.03%]
牻牛儿醇通过调节TRPM2/NMDAR途径改善缺血诱导的海马神经元病理衰老和认知障碍
Zhan-Zhou Fu,Qian-Qian Niu,Chun-Rui Zhang et al.
Zhan-Zhou Fu et al.
Vascular dementia (VaD) is associated with chronic cerebral hypoperfusion, oxidative stress, mitochondrial dysfunction, and hippocampal neuronal senescence. Citronellal (CT) ameliorates cognitive impairment in 2VO-induced VaD rats. CT impro...